Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Shanaz A Ghandhi"'
Autor:
Shanaz A Ghandhi, Helen C Turner, Igor Shuryak, Gregory O Dugan, J Daniel Bourland, John D Olson, Janet A Tooze, Shad R Morton, Ines Batinic-Haberle, J Mark Cline, Sally A Amundson
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191402 (2018)
We investigated the cytogenetic and gene expression responses of peripheral blood cells of non-human primates (NHP, Macaca mulatta) that were whole-thorax irradiated with a single dose of 10 Gy. In this model, partial irradiation of NHPs in the thora
Externí odkaz:
https://doaj.org/article/1e8da8efebcb4ad0be2450ba9f567b80
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99983 (2014)
Downstream factors that regulate the decision between senescence and cell death have not been elucidated. Cells undergo senescence through three pathways, replicative senescence (RS), stress-induced premature senescence (SIPS) and oncogene-induced se
Externí odkaz:
https://doaj.org/article/940ca36ef6df41bb988ac116756b23b7
Autor:
Igor Shuryak, Shanaz A. Ghandhi, Evagelia C. Laiakis, Guy Garty, Xuefeng Wu, Brian Ponnaiya, Emma Kosowski, Evan Pannkuk, Salan P. Kaur, Andrew D. Harken, Naresh Deoli, Albert J. Fornace, David J. Brenner, Sally A. Amundson
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract There is a persistent risk of a large-scale malicious or accidental exposure to ionizing radiation that may affect a large number of people. Exposure will consist of both a photon and neutron component, which will vary in magnitude between i
Externí odkaz:
https://doaj.org/article/2d5470e0716145d4af6f52e648b8df37
Autor:
Shanaz A. Ghandhi, Shad R. Morton, Igor Shuryak, Younghyun Lee, Rajesh K. Soni, Jay R. Perrier, James Bakke, Janet Gahagan, Kim Bujold, Simon Authier, Sally A. Amundson, David J. Brenner, Denise Nishita, Polly Chang, Helen C. Turner
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-21 (2023)
Abstract Background Non-human primates, such as Rhesus macaques, are a powerful model for studies of the cellular and physiological effects of radiation, development of radiation biodosimetry, and for understanding the impact of radiation on human he
Externí odkaz:
https://doaj.org/article/e3eec020d628404887323c5ef5dd4b5f
Autor:
Shanaz A. Ghandhi, Igor Shuryak, Brian Ponnaiya, Xuefeng Wu, Guy Garty, Shad R. Morton, Salan P. Kaur, Sally A. Amundson
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract In the search for biological markers after a large-scale exposure of the human population to radiation, gene expression is a sensitive endpoint easily translatable to in-field high throughput applications. Primarily, the ex-vivo irradiated h
Externí odkaz:
https://doaj.org/article/9de30514b5ad4bb9b2e46308503c5d27
Autor:
Evan L. Pannkuk, Evagelia C. Laiakis, Guy Garty, Shivani Bansal, Brian Ponnaiya, Xuefeng Wu, Shanaz A. Ghandhi, Sally A. Amundson, David J. Brenner, Albert J. Fornace
Publikováno v:
Metabolites, Vol 12, Iss 6, p 520 (2022)
High-throughput biodosimetry methods to determine exposure to ionizing radiation (IR) that can also be easily scaled to multiple testing sites in emergency situations are needed in the event of malicious attacks or nuclear accidents that may involve
Externí odkaz:
https://doaj.org/article/055489096af5448ea82ca8a8ba039730
Autor:
Evan L. Pannkuk, Evagelia C. Laiakis, Guy Y. Garty, Brian Ponnaiya, Xuefeng Wu, Igor Shuryak, Shanaz A. Ghandhi, Sally A. Amundson, David J. Brenner, Albert J. Fornace
Publikováno v:
Radiation Research.
Novel biodosimetry assays for use in preparedness and response to potential malicious attacks or nuclear accidents would ideally provide accurate dose reconstruction independent of the idiosyncrasies of a complex exposure to ionizing radiation. Compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::610c885cf4ae78be0f93d79b9ac5a0c2
https://doi.org/10.1667/rade-22-00211.1
https://doi.org/10.1667/rade-22-00211.1
Autor:
Shad R. Morton, Guy Garty, David J. Brenner, Evan L. Pannkuk, Shanaz A. Ghandhi, Monica Pujol-Canadell, Sally A. Amundson, Michael Girgis, Albert J. Fornace, Evagelia C. Laiakis
Publikováno v:
J Proteome Res
An important component of ionizing radiation (IR) exposure after a radiological incident may include low-dose rate (LDR) exposures either externally or internally, such as from 137Cs deposition. In this study, a novel irradiation system, VAriable Dos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b46db673783eb2ed4b23130c8ff0d860
https://doi.org/10.1021/acs.jproteome.1c00638
https://doi.org/10.1021/acs.jproteome.1c00638
Autor:
Shanaz A. Ghandhi, Shad. R. Morton, Igor Shuryak, Younghyun Lee, Rajesh K. Soni, Jay R. Perrier, James Bakke, Janet Gahagan, Kim Bujold, Simon Authier, Sally A. Amundson, David J. Brenner, Denise Nishita, Polly Chang, Helen C. Turner
Background: Non-human primates, such as Rhesus macaques, are a powerful model for studies of the cellular and physiological effects of radiation, development of radiation biodosimetry, and for understanding the impact of radiation on human health. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adf43ece272c42143db9a7db51bf60ae
https://doi.org/10.21203/rs.3.rs-2160155/v1
https://doi.org/10.21203/rs.3.rs-2160155/v1
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
In the event of a nuclear attack or radiation event, there would be an urgent need for assessing and reconstructing the dose to which hundreds or thousands of individuals were exposed. These measurements would need a rapid assay to facilitate triage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10140469f50a9e484e59d3d77c590aa2
http://link.springer.com/article/10.1038/s41598-019-54967-5
http://link.springer.com/article/10.1038/s41598-019-54967-5