Factors influencing estimates of HIV-1 infection timing using BEAST.

Autor: Bethany Dearlove, Sodsai Tovanabutra, Christopher L Owen, Eric Lewitus, Yifan Li, Eric Sanders-Buell, Meera Bose, Anne-Marie O'Sullivan, Gustavo Kijak, Shana Miller, Kultida Poltavee, Jenica Lee, Lydia Bonar, Elizabeth Harbolick, Bahar Ahani, Phuc Pham, Hannah Kibuuka, Lucas Maganga, Sorachai Nitayaphan, Fred K Sawe, Jerome H Kim, Leigh Anne Eller, Sandhya Vasan, Robert Gramzinski, Nelson L Michael, Merlin L Robb, Morgane Rolland, RV217 Study Team

Publikováno v: PLoS Computational Biology, Vol 17, Iss 2, p e1008537 (2021)

While large datasets of HIV-1 sequences are increasingly being generated, many studies rely on a single gene or fragment of the genome and few comparative studies across genes have been done. We performed genome-based and gene-specific Bayesian phylo

Externí odkaz: https://doaj.org/article/b0c174c950ec4182833e083b931ec6e3

Sieve analysis of breakthrough HIV-1 sequences in HVTN 505 identifies vaccine pressure targeting the CD4 binding site of Env-gp120.

Autor: Allan C deCamp, Morgane Rolland, Paul T Edlefsen, Eric Sanders-Buell, Breana Hall, Craig A Magaret, Andrew J Fiore-Gartland, Michal Juraska, Lindsay N Carpp, Shelly T Karuna, Meera Bose, Steven LePore, Shana Miller, Annemarie O'Sullivan, Kultida Poltavee, Hongjun Bai, Kalpana Dommaraju, Hong Zhao, Kim Wong, Lennie Chen, Hasan Ahmed, Derrick Goodman, Matthew Z Tay, Raphael Gottardo, Richard A Koup, Robert Bailer, John R Mascola, Barney S Graham, Mario Roederer, Robert J O'Connell, Nelson L Michael, Merlin L Robb, Elizabeth Adams, Patricia D'Souza, James Kublin, Lawrence Corey, Daniel E Geraghty, Nicole Frahm, Georgia D Tomaras, M Juliana McElrath, Lisa Frenkel, Sheila Styrchak, Sodsai Tovanabutra, Magdalena E Sobieszczyk, Scott M Hammer, Jerome H Kim, James I Mullins, Peter B Gilbert

Publikováno v: PLoS ONE, Vol 12, Iss 11, p e0185959 (2017)

Although the HVTN 505 DNA/recombinant adenovirus type 5 vector HIV-1 vaccine trial showed no overall efficacy, analysis of breakthrough HIV-1 sequences in participants can help determine whether vaccine-induced immune responses impacted viruses that

Externí odkaz: https://doaj.org/article/a98b506eef10499fa4bd6e7bb5f122ff

RV144 vaccine imprinting constrained HIV-1 evolution following breakthrough infection

Autor: Peter B. Gilbert, Steven Lepore, Hongjun Bai, James I. Mullins, Sorachai Nitayaphan, Hong Zhao, Vincent Dussupt, Morgane Rolland, Paul T. Edlefsen, Sodsai Tovanabutra, Holly Janes, Kultida Poltavee, Nelson L. Michael, Supachai Rerks-Ngarm, Shelly J. Krebs, Sandhya Vasan, Yifan Li, Punnee Pitisuttithum, Joshua T. Herbeck, Jaranit Kaewkungwal, Meera Bose, Robert Gramzinski, Rebecca Grande, Eric Lewitus, Lennie Chen, Gina Donofrio, Ursula Tran, Kim G. Wong, Merlin L. Robb, Thembi Mdluli, Jerome H. Kim, Anne Marie O'Sullivan, Sevan Muhammad, Shana Miller, Bonnie M. Slike, Jenica Lee, Bahar Ahani, Eric Sanders-Buell, Robert J. O'Connell, Letzibeth Mendez-Rivera

Publikováno v: Virus Evolution

The scale of the HIV-1 epidemic underscores the need for a vaccine. The multitude of circulating HIV-1 strains together with HIV-1’s high evolvability hints that HIV-1 could adapt to a future vaccine. Here, we wanted to investigate the effect of va

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac39a74d79d22424517d39ec4deb589e
https://doi.org/10.1093/ve/veab057

Factors influencing estimates of HIV-1 infection timing using BEAST

Autor: Elizabeth A. Harbolick, Hannah Kibuuka, Leigh Anne Eller, Bethany L. Dearlove, Lydia Bonar, Yifan Li, Sodsai Tovanabutra, Robert Gramzinski, Phuc Pham, Eric Lewitus, Merlin L. Robb, Jerome H. Kim, Meera Bose, Sandhya Vasan, Annemarie O'Sullivan, Lucas Maganga, Shana Miller, Sorachai Nitayaphan, Morgane Rolland, Gustavo H. Kijak, Jenica Lee, Fred Sawe, Christopher L. Owen, Nelson L. Michael, Eric Sanders-Buell, Kultida Poltavee, Bahar Ahani

Publikováno v: PLoS computational biology, 17(2):e1008537. Public Library of Science
PLoS Computational Biology, Vol 17, Iss 2, p e1008537 (2021)
PLoS Computational Biology

While large datasets of HIV-1 sequences are increasingly being generated, many studies rely on a single gene or fragment of the genome and few comparative studies across genes have been done. We performed genome-based and gene-specific Bayesian phylo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1c79c66c71c755fc389a152fc1c6196
https://doi.org/10.1371/journal.pcbi.1008537

Centralized HIV Program Oversight

Autor: Nelson L. Michael, Sheila A. Peel, Rupal M. Mody, Michael Price, Sodsai Tovanabutra, Stephanie L. Scoville, Shana Miller, Eric Sanders-Buell, Phuc Pham, Shilpa Hakre, Paul T. Scott, Linda L. Jagodzinski, Ying Liu, Gustavo H. Kijak, Otha Myles, Laura A. Pacha, Jerome H. Kim, Steven B. Cersovsky

Publikováno v: Medicine. 94:e2093

Centralized HIV program oversight and repeal of the Department of Defense policy "Don't Ask Don't Tell" permitted characterization of HIV transmission among soldiers assigned to a large US Army base continental United States from 2012 to 2013. An inv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9a85ae25d933e2cff44733e3909ebb0d
https://doi.org/10.1097/md.0000000000002093