Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Shana M. Katzman"'
Autor:
Stuart Smith, Andrzej Witkowski, Ayesha Moghul, Yuko Yoshinaga, Michael Nefedov, Pieter de Jong, Dejiang Feng, Loren Fong, Yiping Tu, Yan Hu, Stephen G Young, Thomas Pham, Carling Cheung, Shana M Katzman, Martin D Brand, Casey L Quinlan, Marcel Fens, Frans Kuypers, Stephanie Misquitta, Stephen M Griffey, Son Tran, Afshin Gharib, Jens Knudsen, Hans Kristian Hannibal-Bach, Grace Wang, Sandra Larkin, Jennifer Thweatt, Saloni Pasta
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47196 (2012)
A mouse model with compromised mitochondrial fatty acid synthesis has been engineered in order to assess the role of this pathway in mitochondrial function and overall health. Reduction in the expression of mitochondrial malonyl CoA-acyl carrier prot
Externí odkaz:
https://doaj.org/article/9075ccbc571d4a01888a6b5716bb334c
Autor:
Stephen B. Kritchevsky, Steven R. Cummings, Anne B. Newman, Jeanne E. Maglione, Tamara B. Harris, Gregory J. Tranah, Kristine Yaffe, Shana M. Katzman, Todd M. Manini
Publikováno v:
International Journal of Geriatric Psychiatry. 33:1319-1326
OBJECTIVES Mitochondrial DNA (mtDNA) heteroplasmy is a mixture of normal and mutated mtDNA molecules in a cell. High levels of heteroplasmy at several mtDNA sites in complex I lead to inherited neurological neurologic diseases and brain magnetic reso
Autor:
Anne B. Newman, Shana M. Katzman, Steven R. Cummings, Kristine Yaffe, Todd M. Manini, Tamara B. Harris, Kevin Lauterjung, Gregory J. Tranah, Stephen B. Kritchevsky
Publikováno v:
Tranah, Gregory J; Katzman, Shana M; Lauterjung, Kevin; Yaffe, Kristine; Manini, Todd M; Kritchevsky, Stephen; et al.(2018). Mitochondrial DNA m.3243A > G heteroplasmy affects multiple aging phenotypes and risk of mortality.. Scientific reports, 8(1), 11887. doi: 10.1038/s41598-018-30255-6. UCSF: Retrieved from: http://www.escholarship.org/uc/item/6wn1v51t
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Scientific reports, vol 8, iss 1
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Scientific reports, vol 8, iss 1
Scientific Reports
Mitochondria contain many copies of a circular DNA molecule (mtDNA), which has been observed as a mixture of normal and mutated states known as heteroplasmy. Elevated heteroplasmy at a single mtDNA site, m.3243A > G, leads to neurologic, sensory, mov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb63c00000ebfe57af6be22aec46360d
http://www.escholarship.org/uc/item/6wn1v51t
http://www.escholarship.org/uc/item/6wn1v51t
Autor:
Ernest T. Lam, Anne B. Newman, Jennifer S. Yokoyama, Mike A. Nalls, Fridtjof Thomas, Shana M. Katzman, Tamara B. Harris, Yiqiang Zhao, Yongmei Liu, Sean D. Mooney, Kristine Yaffe, Gregory J. Tranah, Steven R. Cummings
Publikováno v:
Journal of Alzheimer's Disease. 32:357-372
Mitochondrial dysfunction is a prominent hallmark of Alzheimer's disease (AD). Mitochondrial DNA (mtDNA) damage may be a major cause of abnormal reactive oxidative species production in AD or increased neuronal susceptibility to oxidative injury duri
Autor:
Anne B. Newman, Kristine Yaffe, Michael B. Gorin, Todd M. Manini, Elizabeth Helzner, Pui-Yan Kwok, Steven R. Cummings, Anne L. Coleman, Nicholas J. Schork, Shana M. Katzman, Ludmila Pawlikowska, Ernest T. Lam, Michael C. Rowbotham, Fridtjof Thomas, Warren S. Browner, Stephen B. Kritchevsky, Gregory J. Tranah, Tamara B. Harris
Background: Mitochondrial DNA (mtDNA) heteroplasmy is a mixture of normal and mutated mtDNA molecules in a cell. High levels of heteroplasmy at specific mtDNA sites lead to inherited mitochondrial diseases with neurological, sensory, and movement imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46474047a6afed50c5efbba2f17b1e83
https://europepmc.org/articles/PMC4612388/
https://europepmc.org/articles/PMC4612388/
Publikováno v:
Environmental Biology of Fishes. 66:15-18
The leopard shark, Triakis semifasciata, regularly resides in California's Tomales Bay, which is characterized by thermally different regions ranging from 10°C to 26°C during the summer. Past studies have shown that leopard sharks feed on benthic i
Publikováno v:
Copeia. 2002:462-465
We measured resting routine oxygen consumption rates (MO2, in mg O2 · h−1 · kg−0.67) of bat rays (Myliobatis californica) under two seawater (33, 35 ppt) and two brackish (15, 25 ppt) salinity conditions. A significant increase in MO2 was obser
Autor:
Sean D. Mooney, Nik Schork, Yongmei Liu, Tamara B. Harris, Anne B. Newman, Steven R. Cummings, Elsa S. Strotmeyer, Gregory J. Tranah, Kristine Yaffe, Yiqiang Zhao, Shana M. Katzman, Mike A. Nalls
Publikováno v:
The journals of gerontology. Series A, Biological sciences and medical sciences. 70(11)
Background. Mitoc hondrial dysfunction is a prominent hallmark of many sensory neuropathies. The purpose of this study was to assess the influence of mitochondrial DNA sequence variation on peripheral nerve function in the population-based Health, Ag
Juvenile Coho Salmon Locomotion and Mosaic Muscle are Modified by 3’,3’,5’-Tri-Iodo-L-Thyronine (T3)
Autor:
Shana M. Katzman, Joseph J. Cech
Publikováno v:
Journal of Experimental Biology. 204:1711-1717
Studies of maximum aerobic swimming performance in smolting juvenile salmonids indicate that these animals may be aerobically compromised during downstream migration. To test our hypothesis that hyperthyroid status contributes to decreased swimming p
Autor:
Pui-Yan Kwok, Steven R. Cummings, Tamara B. Harris, Shana M. Katzman, Daniel S. Evans, Sean D. Mooney, Mike A. Nalls, Stephen B. Kritchevsky, Anne B. Newman, Gregory J. Tranah, Yiqiang Zhao, Ludmila Pawlikowska, Todd M. Manini, Jennifer S. Yokoyama, Bret H. Goodpaster, Ernest T. Lam
The decline in activity energy expenditure underlies a range of age-associated pathological conditions, neuromuscular and neurological impairments, disability, and mortality. The majority (90%) of the energy needs of the human body are met by mitocho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e601860c42767f74ebc71610442367bb
https://europepmc.org/articles/PMC3389152/
https://europepmc.org/articles/PMC3389152/