Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Shana M. Augustin"'
Autor:
Armando G. Salinas, Jeong Oen Lee, Shana M. Augustin, Shiliang Zhang, Tommaso Patriarchi, Lin Tian, Marisela Morales, Yolanda Mateo, David M. Lovinger
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract The development of genetically encoded dopamine sensors such as dLight has provided a new approach to measuring slow and fast dopamine dynamics both in brain slices and in vivo, possibly enabling dopamine measurements in areas like the dorso
Externí odkaz:
https://doaj.org/article/00c2d19f80214233be1c3432d94f4dc6
Autor:
Shana M. Augustin, David M. Lovinger
Publikováno v:
Neurobiology of Disease, Vol 167, Iss , Pp 105670- (2022)
The legalization of cannabis in many countries, as well as the decrease in perceived risks of cannabis, have contributed to the increase in cannabis use medicinally and recreationally. Like many drugs of abuse, cannabis and cannabis-derived drugs are
Externí odkaz:
https://doaj.org/article/d0433e0172964839bdd536ad58d45308
Autor:
Armando G. Salinas, Jacob A. Nadel, Yolanda Mateo, Thanh Huynh, Shana M. Augustin, Karel Pacak, David M. Lovinger
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 10994 (2022)
Alcohol use disorder (AUD) is characterized by escalating alcohol consumption, preoccupation with alcohol, and continued alcohol consumption despite adverse consequences. Dopamine has been implicated in neural and behavioral processes involved in rew
Externí odkaz:
https://doaj.org/article/cdb7b76f85424777879a2b570eb9f459
Publikováno v:
Cell Reports, Vol 24, Iss 11, Pp 2883-2893 (2018)
Summary: Endocannabinoid (eCB)-mediated long-term depression (LTD) requires dopamine (DA) D2 receptors (D2Rs) for eCB mobilization. The cellular locus of the D2Rs involved in LTD induction remains highly debated. We directly examined the role in LTD
Externí odkaz:
https://doaj.org/article/9a33080d2de943feba933e2a6b582b3a
Autor:
Armando G. Salinas, Jeong O. Lee, Shana M. Augustin, Shiliang Zhang, Tommaso Patriarchi, Lin Tian, Marisela Morales, Yolanda Mateo, David M. Lovinger
Dopamine produces neuromodulation throughout the basal ganglia, cortex and other brain regions, and is implicated in movement control, neural mechanisms of reward and actions of misused substances. The efferent projections of dopaminergic neurons wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9ff9bc7bc436249f44c215f1ac51cfd
https://doi.org/10.1101/2022.01.09.475513
https://doi.org/10.1101/2022.01.09.475513
Publikováno v:
The Journal of Neuroscience. 39:1457-1470
Dynamic regulation of synaptic transmission at cortical inputs to the dorsal striatum is considered critical for flexible and efficient action learning and control. Presynaptic mechanisms governing the properties and plasticity of glutamate release f
Autor:
Shana M. Augustin, Timothy J. O’Neal, Alexxai V. Kravitz, David M. Lovinger, Gabriel C. Loewinger
Publikováno v:
Neuropsychopharmacology
Striatal dopamine D2 receptors (D2Rs) are important for motor output. Selective deletion of D2Rs from indirect pathway-projecting medium spiny neurons (iMSNs) impairs locomotor activities in a task-specific manner. However, the role of D2Rs in the in
Publikováno v:
Cell Reports, Vol 24, Iss 11, Pp 2883-2893 (2018)
Summary: Endocannabinoid (eCB)-mediated long-term depression (LTD) requires dopamine (DA) D2 receptors (D2Rs) for eCB mobilization. The cellular locus of the D2Rs involved in LTD induction remains highly debated. We directly examined the role in LTD
Autor:
Oakleigh M. Folkes, Danny G. Winder, Ken Mackie, Shana M. Augustin, Walker P. Parrish, Samuel W. Centanni, Jason R. Stephenson, Roger J. Colbran, David M. Lovinger, Hala K. Haddad, Sachin Patel, Brian C. Shonesy, Keeley L. Spiess, Rebecca J. Bluett, Rita Báldi, Christian R. Marks
Publikováno v:
Biological Psychiatry. 84:304-315
Background Endocannabinoid signaling plays an important role in regulating synaptic transmission in the striatum, a brain region implicated as a central node of dysfunction in autism spectrum disorder. Deficits in signaling mediated by the endocannab
Autor:
David M. Lovinger, Shana M. Augustin
Publikováno v:
ACS Chemical Neuroscience. 9:2146-2161
The endocannabinoid (eCB) signaling system plays a key role in short-term and long-term synaptic plasticity in brain regions involved in various neural functions ranging from action selection to appetite control. This review will explore the role of