Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Shan-Liang Li"'
Autor:
Chang Chen, Jin-Lai Gao, Ming-Yu Liu, Shan-Liang Li, Xiu-Chen Xuan, Xin-Zi Zhang, Xi-Yue Zhang, Yuan-Yuan Wei, Chang-Lin Zhen, Jing Jin, Xin Shen, De-Li Dong
Publikováno v:
Cellular Physiology and Biochemistry, Vol 42, Iss 5, Pp 1802-1811 (2017)
Background/Aims: Endothelin-1 is implicated in the pathogenesis of hypertension, but the underlying mechanisms remained elusive. Our previous study found that inhibition of mitochondrial fission of smooth muscle cells suppressed phenylephrine- and hi
Externí odkaz:
https://doaj.org/article/e46111f211e24d878b74289e3e9646e9
Publikováno v:
Journal of Cancer Research and Therapeutics, Vol 14, Iss 4, Pp 754-759 (2018)
Purpose: A survival benefit may be associated with the positive control of extrahepatic lymph node metastasis (LNM) of hepatocellular carcinoma (HCC). However, no standard treatment exists. The aim of this study was to evaluate the safety and efficac
Autor:
Zhi-Jie Sun, Xin Shen, De-Li Dong, Li Li, Chang-Lin Zhen, Yufeng Zheng, Rui Ma, Zhen-Gang Ma, Shan-Liang Li
Publikováno v:
Materials Science and Engineering: C. 77:352-359
We have found that niclosamide induced relaxation of constricted artery. However, niclosamide is insoluble, the low bioavailability and the resultant low plasma concentration limit its potential exertion in vivo. The aim of the present study is to sy
Autor:
Zhi-Jie Sun, Nan Hu, Yu Tai, Jing Jin, Yan-Qiu Zhang, Shan-Liang Li, Ming-Yu Liu, Jie Yan, Xiaolin Xiao, Jin-Lai Gao, Chang-Lin Zhen, Xin Shen, De-Li Dong, Xin-Zi Zhang
Publikováno v:
Pharmacological Research. 115:78-86
We previously demonstrated that the typical mitochondrial uncoupler carbonyl cyanide m-chlorophenylhydrazone (CCCP) inhibited artery constriction, but CCCP was used only as a pharmacological tool. Niclosamide is an anthelmintic drug approved by FDA.
Autor:
Liang-Shuan Zhang, Shan-Liang Li, Xiaolin Xiao, De-Li Dong, Jin-Lai Gao, Xin-Zi Zhang, Yan-Qiu Zhang, Yu Tai, Yunlong Bai, Chang-Lin Zhen, Jie Yan, Nan Hu, Jing Jin, Xin Shen, Ming-Yu Liu
Publikováno v:
British Journal of Pharmacology. 173:3145-3158
Background and purpose: The effects and mechanisms of chemical mitochondrial uncouplers on vascular function have never been identified. Here, we characterized the effects of the typical mitochondrial uncoupler carbonyl cyanide m-chlorophenylhydrazon
Autor:
Yan-Qiu Zhang, Chun-Yan Ma, Ming-Yu Liu, Shan-Liang Li, Jie Yan, Xin Shen, Yuan-Yuan Wei, Jin-Lai Gao, Na Li, Chang-Lin Zhen, Yu Zhao, Chen-Guang Wang, De-Li Dong, Yong-Hui Zhang
Publikováno v:
European Journal of Pharmacology. 774:118-126
The bile acids (BAs) and their conjugates have vascular activities and the serum levels of BAs and their conjugates are increased in liver diseases. In the present study, we examined the in vitro vasoactivities of BAs conjugates taurochenodeoxycholat
Publikováno v:
Journal of cancer research and therapeutics. 14(4)
A survival benefit may be associated with the positive control of extrahepatic lymph node metastasis (LNM) of hepatocellular carcinoma (HCC). However, no standard treatment exists. The aim of this study was to evaluate the safety and efficacy of iodi
Autor:
Xi-Yue Zhang, De-Li Dong, Xin-Zi Zhang, Ming-Yu Liu, Xin Shen, Shan-Liang Li, Chang-Lin Zhen, Yu Tai, Jing Jin, Xiu-Chen Xuan, Nan Hu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 7, Iss 3, Pp 319-325 (2017)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Mitochondria are morphologically dynamic organelles which undergo fission and fusion processes. Our previous study found that arterial constriction was always accompanied by increased mitochondrial fission in smooth muscle cells, whereas inhibition o
Autor:
Shan-Liang Li, Hong-Chao Jiang, Qi Li, Ming-Yu Liu, Ying Zhang, Yu-Hong Li, Chao-Wei Hu, De-Li Dong, Wei Han
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 466:2049-2057
Cardiac T-type Ca(2+) channels are reexpressed in atrial and ventricular myocytes under various pathological conditions such as post-myocardial infarction, hypertrophy, and heart failure, but relatively little is known about the mechanisms. Our previ
Autor:
Chang-Lin Zhen, Yunlong Bai, Shan-Liang Li, Xin Shen, Jing Jin, Jin-Lai Gao, Yu Zhao, Yong-Hui Zhang, Yan-Qiu Zhang, Chen-Guang Wang, De-Li Dong, Jie Yan, Yuan-Yuan Wei, Ming-Yu Liu, Liang-Shuan Zhang
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 68(5)
Mitochondria are dynamic organelles and continuously undergo fission and fusion processes. Mitochondrial fission is involved in multiple physiological or pathological processes, but the role of mitochondrial fission of smooth muscle cells in artery c