Výsledky vyhledávání

Akademický článek

High expression of IGFBP7 in fibroblasts induced by colorectal cancer cells is co-regulated by TGF-β and Wnt signaling in a Smad2/3-Dvl2/3-dependent manner.

Autor: Cui Rao, Shan-Li Lin, Wen-Jing Ruan, Huan Wen, Dan-Ju Wu, Hong Deng

Publikováno v: PLoS ONE, Vol 9, Iss 1, p e85340 (2014)

Fibroblasts in the tumor microenvironment are a key determinant in cancer progression and may be a promising target for cancer therapy. Insulin-like growth factor binding protein 7 (IGFBP7) is known as a tumor suppressor in colorectal cancer (CRC). T

Externí odkaz: https://doaj.org/article/da2dc10e2c3c43af8ad1f9f2e4035172

Zobrazit plný text záznamu

[Crosstalk between canonical TGF-β/Smad and Wnt/β-catenin signaling pathway]

Autor: Cui, Rao, Shan-Li, Lin, Huan, Wen, Hong, Deng

Publikováno v: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences. 42(5)

TGF-β signaling pathway plays a central role in the signaling networks that control the growth, differentiation of the cell, and the initiation of fibrosis and cancer. Wnt signaling pathway is critical for the embryonic development and the invasion

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6fc54c13f72ebeb511ce1ff5ebdc7faf
https://pubmed.ncbi.nlm.nih.gov/24167144

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání