Zobrazeno 1 - 10
of 270
pro vyhledávání: '"Shan Man"'
Publikováno v:
Geography and Sustainability, Vol 5, Iss 1, Pp 77-88 (2024)
In the context of economic globalization, while multinational enterprises from developed countries occupy a high-end position in the global value chain, enterprises from developing countries are often marginalized in the world market. In China, resou
Externí odkaz:
https://doaj.org/article/6f441dd38b504dbaaaf211d9d278d1a3
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-16 (2019)
Abstract Background Triple negative breast cancer (TNBC) is an aggressive malignancy with poor prognosis, in part because of the current lack of any approved molecularly targeted therapy. We evaluated various combinations of three different drugs: ni
Externí odkaz:
https://doaj.org/article/03b6d244b7c24be2ba561f6b2a274258
Publikováno v:
Complexity, Vol 2021 (2021)
Urban economic resilience provides a novel perspective on the sustainable development of urban and regional economy. Selecting 37 prefecture-level cities in the Northeast China that also known as the rust belt in China as a regional study sample that
Externí odkaz:
https://doaj.org/article/74c8acd113b047a79d185cd8f3d8507c
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 9, Pp n/a-n/a (2020)
Abstract Conventional maximum‐tolerated dose (MTD) chemotherapy relies on periodic, massive cancer cell ablation events followed by treatment‐free intermissions, stereotypically resulting in resistance, relapse, and mortality. Furthermore, MTD ch
Externí odkaz:
https://doaj.org/article/0b3e5cb868fd4fc29e19318ae9960787
Autor:
Raquel Muñoz, Denise Hileeto, William Cruz-Muñoz, Geoffrey A Wood, Ping Xu, Shan Man, Alicia Viloria-Petit, Robert S Kerbel
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0222580 (2019)
Metronomic chemotherapy using the 5-FU prodrug uracil-tegafur (UFT) and cyclophosphamide (CTX) was previously shown to only modestly delay primary tumor growth, but nevertheless markedly suppressed the development of micro-metastasis in an orthotopic
Externí odkaz:
https://doaj.org/article/887d9a76c7014cc09b1151516c978166
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0158034 (2016)
Several approaches are being evaluated to improve the historically limited value of studying transplanted primary tumors derived by injection of cells from established cell lines for predicting subsequent cancer therapy outcomes in patients and clini
Externí odkaz:
https://doaj.org/article/ba1c2a9cd7224106be427e0af88c80fd
Autor:
Urban Emmenegger, Giulio Francia, Annabelle Chow, Yuval Shaked, Andrew Kouri, Shan Man, Robert S. Kerbel
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 13, Iss 1, Pp 40-48 (2011)
Low-dose metronomic (LDM) chemotherapy is emerging as an alternative or supplemental dosing strategy to conventional maximum tolerated dose (MTD) chemotherapy. It is characterized primarily, but not exclusively, by antiangiogenic mechanisms of action
Externí odkaz:
https://doaj.org/article/69848885684c4672bf9a79025fe2a446
Autor:
Terence C. Tang, Shan Man, Ping Xu, Giulio Francia, Kae Hashimoto, Urban Emmenegger, Robert S. Kerbel
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 12, Iss 11, Pp 928-940 (2010)
Acquired resistance to antiangiogenic drugs, such as sorafenib, is a major clinical problem. We studied development of a resistance to sorafenib in new preclinical models of human hepatocellular carcinoma (HCC) along with a strategy to delay such res
Externí odkaz:
https://doaj.org/article/7d4360fe233b43e3a0454b3cd2ae3f7a
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 12, Iss 3, Pp 264-274 (2010)
Hepatocellular carcinoma (HCC) is an intrinsically chemotherapy refractory malignancy. Development of effective therapeutic regimens would be facilitated by improved preclinical HCC models. Currently, most models consist of subcutaneous human tumor t
Externí odkaz:
https://doaj.org/article/35d0bf024a5b4449a582419bf06e5ed1
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71270 (2013)
We compare for the first time, the metastatic aggressiveness of the parental MDA-MB-231 breast cancer cell line and two luciferase-tagged in vivo-derived and selected pro-metastatic variants (LM2-4/luc⁺ and 164/8-1B/luc⁺ in SCID, NOD-SCID and NOD
Externí odkaz:
https://doaj.org/article/ddacaa41dde14678a8057a6ad261d61b