Genetic predisposition to cancer across people of different ancestries in Qatar: a population-based, cohort study

Autor: Ismail, Said I, Al-Muftah, Wadha, Badji, Radja, Mbarek, Hamdi, Darwish, Dima, Fadl, Tasnim, Yasin, Heba, Ennaifar, Maryem, Abdellatif, Rania, Alkuwari, Fatima, Alvi, Muhammad, Al-Sarraj, Yasser, Saad, Chadi, Fethnou, Eleni, Qafoud, Fatima, Alkhayat, Eiman, Afifi, Nahla, Tomei, Sara, Liu, Wei, Lorenz, Stephan, Syed, Najeeb, Almabrazi, Hakeem, Vempalli, Fazulur R, Temanni, Ramzi, Abu Saqri, Tariq, Khatib, Mohammedhusen, Hamza, Mehshad, Abu Zaid, Tariq, El Khouly, Ahmed, Pathare, Tushar, Poolat, Shafeeq, Al-Ali, Rashid, Albagha, Omar, Al-Khodor, Souhaila, Alshafai, Mashael, Badii, Ramin, Chouchane, Lotfi, Estivill, Xavier, Fakhro, Khalid, Mokrab, Younes, Puthen, Jithesh V, Suhre, Karsten, Tatari, Zohreh, Saad, Mohamad ^*, Halabi, Najeeb ^*, Shan, Jingxuan, Razali, Rozaimi, Kunji, Khalid, Subramanian, Murugan, Ceccarelli, Michele, Rafii Tabrizi, Arash, Bedognetti, Davide

Publikováno v: In The Lancet Oncology March 2022 23(3):341-352

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STXBP6, reciprocally regulated with autophagy, reduces triple negative breast cancer aggressiveness.

Autor: Lenka, Govinda^1,2 (AUTHOR), Shan, Jingxuan^2,3 (AUTHOR), Halabi, Najeeb^2,3 (AUTHOR), Abuaqel, Sirin W J^1,2,3 (AUTHOR), Goswami, Neha⁴ (AUTHOR), Schmidt, Frank⁴ (AUTHOR), Zaghlool, Shaza⁵ (AUTHOR), Romero, Atilio Reyes⁶ (AUTHOR), Subramanian, Murugan^1,2,3 (AUTHOR), Boujassoum, Salha⁷ (AUTHOR), Al‐Bozom, Issam⁸ (AUTHOR), Gehani, Salah⁹ (AUTHOR), Khori, Noor Al¹⁰ (AUTHOR), Bedognetti, Davide¹¹ (AUTHOR), Suhre, Karsten⁵ (AUTHOR), Ma, Xiaojing¹ (AUTHOR), Dömling, Alexander⁶ (AUTHOR), Rafii, Arash^2,3 (AUTHOR), Chouchane, Lotfi^1,2,3 (AUTHOR) loc2008@med.cornell.edu

Publikováno v: Clinical & Translational Medicine. Jul2020, Vol. 10 Issue 3, p1-19. 19p.

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Targeting Wnt/EZH2/microRNA-708 signaling pathway inhibits neuroendocrine differentiation in prostate cancer

Autor: Shan, Jingxuan, Al-Muftah, Mariam A., Al-Kowari, Moza K., Abuaqel, Sirin W. J., Al-Rumaihi, Khalid, Al-Bozom, Issam, Li, Pu, Chouchane, Lotfi

Publikováno v: Cell Death Discovery, Vol 5, Iss 1, Pp 1-13 (2019)
Cell Death Discovery

Prostate cancer (PC) castration resistance has been linked to the differentiation of PC luminal cells into hormone-refractory neuroendocrine (NE) cells. However, the molecular mechanisms controlling the emergence of lethal NE prostate cancer (NEPC) r

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