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pro vyhledávání: '"Shan Chi Ku"'
Autor:
Shan Chi Ku
Neisseria meningitidis is the causative agent of potentially life-threatening meningitis and septicaemia. According to W.H.O., meningococcal disease causes at least 500,000 cases and results in 50,000 deaths worldwide each year (W.H.O., 2008). Neisse
Externí odkaz:
http://espace.library.uq.edu.au/view/UQ:178994
Modulating the function of human serine racemase and human serine dehydratase by protein engineering
Publikováno v:
Protein Engineering Design and Selection. 25:741-749
D-Serine is a co-agonist of N-methyl D-aspartate, a glutamate receptor, which is a major excitatory neurotransmitter receptor in the brain. Human serine racemase (hSR) and serine dehydratase (hSDH) are two important pyridoxal-5'-phosphate-dependent e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7fa1586859af50df4f6de06cf9b216e
https://doi.org/10.1093/protein/gzs078
https://doi.org/10.1093/protein/gzs078
Publikováno v:
Nucleic Acids Research
DNA mimic proteins occupy the DNA binding sites of DNA-binding proteins, and prevent these sites from being accessed by DNA. We show here that the Neisseria conserved hypothetical protein DMP19 acts as a DNA mimic. The crystal structure of DMP19 show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf9139ba2cb59beb914181f2e596833e
https://doi.org/10.1093/nar/gks177
https://doi.org/10.1093/nar/gks177