Zobrazeno 1 - 10
of 890
pro vyhledávání: '"Shan‑Shan Li"'
Diagnosis and prognosis prediction of gastric cancer by high-performance serum lipidome fingerprints
Autor:
Ze-Rong Cai, Wen Wang, Di Chen, Hao-Jie Chen, Yan Hu, Xiao-Jing Luo, Yi-Ting Wang, Yi-Qian Pan, Hai-Yu Mo, Shu-Yu Luo, Kun Liao, Zhao-Lei Zeng, Shan-Shan Li, Xin-Yuan Guan, Xin-Juan Fan, Hai-long Piao, Rui-Hua Xu, Huai-Qiang Ju
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 12, Pp 3089-3112 (2024)
Abstract Early detection is warranted to improve prognosis of gastric cancer (GC) but remains challenging. Liquid biopsy combined with machine learning will provide new insights into diagnostic strategies of GC. Lipid metabolism reprogramming plays a
Externí odkaz:
https://doaj.org/article/d961b8da922348d18607888a9b8ccac9
Publikováno v:
Insights into Imaging, Vol 15, Iss 1, Pp 1-8 (2024)
Abstract Objective This study aims to assess the diagnostic performance of Sonazoid-contrast-enhanced ultrasound (CEUS) in identifying definitive HCC within hepatic nodules in cirrhotic patients, comparing the KLCA-NCC 2022 and APASL 2017 diagnostic
Externí odkaz:
https://doaj.org/article/e19196d50d38420196d2e1c451d8598c
Autor:
Shan-Shan Li, Lu Pan, Zhen-Ye Zhang, Meng-Dan Zhou, Xu-Fei Chen, Ling-Ling Qian, Min Dai, Juan Lu, Zhi-Ming Yu, Shipeng Dang, Ru-Xing Wang
Publikováno v:
Diabetes & Metabolism Journal, Vol 48, Iss 4, Pp 716-729 (2024)
Background Diabetes-induced cardiac fibrosis is one of the main mechanisms of diabetic cardiomyopathy. As a common histone methyltransferase, enhancer of zeste homolog 2 (EZH2) has been implicated in fibrosis progression in multiple organs. However,
Externí odkaz:
https://doaj.org/article/c1758dd2334043b98000374f55d1f0c9
Autor:
Xiao-Yu Zhang, Shan-Shan Li, Yu-Rong Gu, Le-Xin Xiao, Xin-Yi Ma, Xin-Ru Chen, Jia-Liang Wang, Chun-Hong Liao, Bing-Liang Lin, Yue-Hua Huang, Yi-Fan Lian
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-19 (2024)
Abstract Background The role of circRNAs in hepatocellular carcinoma (HCC) progression remains unclear. CircPIAS1 (circBase ID: hsa_circ_0007088) was identified as overexpressed in HCC cases through bioinformatics analysis. This study aimed to invest
Externí odkaz:
https://doaj.org/article/ab3542d189c14f4382118dd603e564b4
Autor:
Jun-Xu Gu, Juan Huang, Kun Wang, Yue Yin, Jun-Ling Fang, Ai-Min Zhang, Shan-Shan Li, Xiao-Qin Yao, Ming Yang, Na Zhang, Mei Jia, Ming Su
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e37415- (2024)
Background: High circulatory lipoprotein(a) [Lp(a)] concentration promotes atherosclerosis; however, its efficacy in predicting the extent of atherosclerotic coronary heart disease (CHD) with coronary artery obstruction and major adverse cardiovascul
Externí odkaz:
https://doaj.org/article/8232cc780dd5431eaf36d5ff39b596e5
Autor:
De-Shen Wang, Chao Ren, Shan-Shan Li, William Pat Fong, Xiao-Jun Wu, Jian Xiao, Bin-Kui Li, Yun Zheng, Pei-Rong Ding, Gong Chen, Miao-Zhen Qiu, Zhi-Qiang Wang, Feng-Hua Wang, Hui-Yan Luo, Feng Wang, Xiao-Zhong Wang, Ling-Yun Wang, De-Jin Xie, Tao Chen, Li-Ren Li, Zhen-Hai Lu, Xiao-Hui Zhai, Tian-Shu Liu, Ying Yuan, Jia-Qi Chen, Qiong Tan, Zhi-Zhong Pan, De-Sen Wan, Rong Zhang, Yun-Fei Yuan, Rui-Hua Xu, Yu-Hong Li
Publikováno v:
PLoS Medicine, Vol 21, Iss 5, p e1004389 (2024)
BackgroundIt remains unclear whether intensification of the chemotherapy backbone in tandem with an anti-EGFR can confer superior clinical outcomes in a cohort of RAS/BRAF wild-type colorectal cancer (CRC) patients with initially unresectable colorec
Externí odkaz:
https://doaj.org/article/b9e6a45661f549378ef2d8ab851edf5e
Association between serum PCSK9 and coronary heart disease in patients with type 2 diabetes mellitus
Autor:
Juan Huang, Jun-Xu Gu, Kun Wang, Ai-Min Zhang, Ting-Ting Hong, Shan-Shan Li, Xiao-Qin Yao, Ming Yang, Yue Yin, Na Zhang, Ming Su, Jia-Jia Hu, Xue-Zhi Zhang, Mei Jia
Publikováno v:
Diabetology & Metabolic Syndrome, Vol 15, Iss 1, Pp 1-12 (2023)
Abstract Background and aims Proprotein convertase subtilisin/kexin type 9 (PCSK9) is considered a new biomarker for atherosclerosis, but its ability to predict cardiovascular outcomes has been controversial. This study aimed to address the lack of d
Externí odkaz:
https://doaj.org/article/992e7a53a8ec41ddab4003097b8ffc96
Autor:
Mei‐Feng Chen, Wei He, De‐Sheng Huang, Hui Jia, Zhao‐Shuang Zhong, Nan Li, Shan‐Shan Li, Shu‐Yue Xia
Publikováno v:
The Clinical Respiratory Journal, Vol 17, Iss 9, Pp 851-864 (2023)
Abstract Objective This study aimed to investigate the effectiveness of doxofylline as an adjuvant in reducing severe exacerbation for different clinical subtypes of chronic obstructive pulmonary disease (COPD). Methods The clinical trial was an open
Externí odkaz:
https://doaj.org/article/1c352a3f3e34401280159c81810c2f6e
Publikováno v:
BMC Pediatrics, Vol 23, Iss 1, Pp 1-5 (2023)
Abstract Background Pediatric pulmonary hypertension (PH) is a serious and rare disease that is often derived from genetic mutations. Kabuki syndrome (KS) is a chromosomal abnormality disease that has its origin in the mutation of lysine methyltransf
Externí odkaz:
https://doaj.org/article/5ee30e37062e44f39473042c717093c9
Publikováno v:
Neurobiology of Disease, Vol 189, Iss , Pp 106347- (2023)
Cerebral small vessel disease (CSVD) causes 20%–25% of stroke and contributes to 45% of dementia cases worldwide. However, since its early symptoms are inconclusive in addition to the complexity of the pathological basis, there is a rather limited
Externí odkaz:
https://doaj.org/article/a664cf47ce064bfaa2377d98d116c87a