Výsledky vyhledávání - "Shan, Jingbo"

Akademický článek

Exogenous damage causes cell DNA damage through mediated reactive oxygen levels

Autor: Guo Peiyan, Ma Ning, Shan Jingbo, Chen Techang, Zhang Yujie, Zhou Sa, Ma Wenjian

Publikováno v: E3S Web of Conferences, Vol 131, p 01018 (2019)

Many anti-tumor drugs can induce tumor apoptosis by increasing intracellular ROS. In the present study, we build a model which did not directly cause DNA damage, but simulated damage products. The model of this injury was transferred into the cell so

Externí odkaz: https://doaj.org/article/953e0715a02e47c38295ae67f776e5da

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Akademický článek

Study on anti-tumor activity of itraconazole in colon cancer

Autor: Li Xiaoqi, Shan Jingbo, Jin Lijun, Li Xinyu, Zhou Sa, Ma Wenjian

Publikováno v: E3S Web of Conferences, Vol 131, p 01017 (2019)

Itraconazole is a common antifungal drug, which inhibiting lanosterol 14 alpha-demethylase, interfering with lanosterol convert to ergosterol or cholesterol, thereby affecting the synthesis of fungal cell membranes. In recent years, it has been found

Externí odkaz: https://doaj.org/article/95431ddbb21242c5af5c29e7f2477a9f

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Akademický článek

Rad51 stabilizes the ends of two adjacent DSBs in yeast

Autor: Chen Techang, Li Xiaoqi, Ma Ning, Shan Jingbo, Guo Peiyan, Zhou Sa, Ma Wenjian

Publikováno v: E3S Web of Conferences, Vol 131, p 01013 (2019)

DNA double-strand breaks (DSBs) are a major form of DNA damage, and its accurate repair is critical for maintaining genomic stability and preventing cancer. Repair of DSBs is mainly through two pathways, homology-directed DNA repair (HDR) and non-hom

Externí odkaz: https://doaj.org/article/3446e35953954378af5faa5109541fcb

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