Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Shamseer Kulangara Kandi"'
Autor:
Woori Kim, Mohit Tripathi, Chunhyung Kim, Satyapavan Vardhineni, Young Cha, Shamseer Kulangara Kandi, Melissa Feitosa, Rohit Kholiya, Eric Sah, Anuj Thakur, Yehan Kim, Sanghyeok Ko, Kaiya Bhatia, Sunny Manohar, Young-Bin Kong, Gagandeep Sindhu, Yoon-Seong Kim, Bruce Cohen, Diwan S. Rawat, Kwang-Soo Kim
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract The nuclear receptor, Nurr1, is critical for both the development and maintenance of midbrain dopamine neurons, representing a promising molecular target for Parkinson’s disease (PD). We previously identified three Nurr1 agonists (amodiaqu
Externí odkaz:
https://doaj.org/article/b81b0d3dcdc14cc4b8e8e7f126ca1dbb
Publikováno v:
ACS Omega, Vol 4, Iss 1, Pp 675-687 (2019)
Externí odkaz:
https://doaj.org/article/2d4aa0a2a56a4ffea32f67d0bef6ecca
Autor:
Garima Arora, Gagandeep, Assirbad Behura, Tannu Priya Gosain, Ravi P. Shaliwal, Saqib Kidwai, Padam Singh, Shamseer Kulangara Kandi, Rohan Dhiman, Diwan S. Rawat, Ramandeep Singh
Publikováno v:
Frontiers in Microbiology, Vol 10 (2020)
The increasing incident rates of drug-resistant tuberculosis (DR-TB) is a global health concern and has been further complicated by the emergence of extensive and total drug-resistant strains. Identification of new chemical entities which are compati
Externí odkaz:
https://doaj.org/article/bd7c19cd90944030be789debdd42df2c
Publikováno v:
ACS Omega, Vol 4, Iss 1, Pp 675-687 (2019)
Curcumin has been known to possess diverse pharmacological effects at relatively nontoxic doses; however, its therapeutic potential is severely restricted because of its low aqueous solubility and poor stability under physiological conditions. To ove
Autor:
Padam Singh, Garima Arora, Rohan Dhiman, Gagandeep, Diwan S. Rawat, Shamseer Kulangara Kandi, Tannu Priya Gosain, Saqib Kidwai, Ravi P. Shaliwal, Ramandeep Singh, Assirbad Behura
Publikováno v:
Frontiers in Microbiology, Vol 10 (2020)
The increasing incident rates of drug-resistant tuberculosis (DR-TB) is a global health concern and has been further complicated by the emergence of extensive and total drug-resistant strains. Identification of new chemical entities which are compati
Autor:
Garima, Arora, Gagandeep, Assirbad, Behura, Tannu Priya, Gosain, Ravi P, Shaliwal, Saqib, Kidwai, Padam, Singh, Shamseer Kulangara, Kandi, Rohan, Dhiman, Diwan S, Rawat, Ramandeep, Singh
Publikováno v:
Frontiers in Microbiology
The increasing incident rates of drug-resistant tuberculosis (DR-TB) is a global health concern and has been further complicated by the emergence of extensive and total drug-resistant strains. Identification of new chemical entities which are compati
Publikováno v:
European Journal of Medicinal Chemistry. 195:112276
In continuation of our effort to improve the physiological stability and the antibacterial activity of curcuminoids against drug-resistant bacteria, a series of novel monocarbonyl curcuminoids were synthesized and screened for antibacterial activity
Autor:
Sanjay V. Malhotra, Diwan S. Rawat, Sunny Manohar, Shamseer Kulangara Kandi, Christian E. Vélez Gerena, Beatriz Zayas
Publikováno v:
New Journal of Chemistry. 39:224-234
The privileged scaffolds of curcumin and 4-aminoquinolines are extensively used in the design and synthesis of biodynamic agents having remarkable efficacy against diseases like cancer and malaria. Therefore, we anticipated that covalent hybridizatio
Autor:
Kranthi Raj, Xiaochuan Yang, Shabana I. Khan, Guojing Sun, Shamseer Kulangara Kandi, Sunny Manohar, Nanting Ni, Angie Dayan Calderon Molina, Binghe Wang, Diwan S. Rawat
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:112-116
A series of novel monocarbonyl analogues of curcumin have been designed, synthesized and tested for their activity against Molt4, HeLa, PC3, DU145 and KB cancer cell lines. Six of the analogues showed potent cytotoxicity towards these cell lines with