Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Shams Ul Mahmood"'
Publikováno v:
Crystals, Vol 1, Iss 3, Pp 171-177 (2011)
Synthesis of the title compound from 4-methoxyaniline was accomplished in three steps. The structure was supported by spectroscopic data and unambiguously confirmed by single crystal X-ray diffraction data. It crystallizes in the monoclinic space gro
Externí odkaz:
https://doaj.org/article/dfa66001ccbc485ca49a15117375c68c
Publikováno v:
ChemistrySelect. 5:5387-5390
Autor:
Tyler Eck, John Gordon, Wayne E. Childers, Brandon S. Pybus, Dennis J. Colussi, Tamara Kreiss, Alison Roth, Rammohan R. Yadav Bheemanaboina, David P. Rotella, Shams Ul Mahmood, Patricia J. Lee, Purnima Bhanot, Samantha O. Aylor, Mariana Laureano de Souza, Mariana Lozano Gonzalez, John J. Siekierka
Publikováno v:
ACS Med Chem Lett
[Image: see text] The discovery of new targets for the treatment of malaria, in particular those aimed at the pre-erythrocytic stage in the life cycle, advanced with the demonstration that orally administered inhibitors of Plasmodium falciparum cGMP-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df8fe3378b6bb8e06313fdebf1e4dbd7
https://europepmc.org/articles/PMC8667308/
https://europepmc.org/articles/PMC8667308/
Autor:
Purnima Bhanot, Mariana Lozano Gonzalez, Brandon S. Pybus, John Gordon, Wayne E. Childers, David P. Rotella, Rammohan R. Yadav Bheemanaboina, Alison Roth, Shams Ul Mahmood, Tamara Kreiss, Tyler Eck, Mariana Laureano de Souza, John J. Siekierka, Dennis J. Colussi, Patricia J. Lee, Samantha O. Aylor
The discovery of new targets for treatment of malaria and in particular those aimed at the pre-erythrocytic stage in the life cycle, advanced with the demonstration that orally administered inhibitors of Plasmodium falciparum cGMP-dependent protein k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77f95d28b1facf94164495dca7105a0f
https://doi.org/10.1101/2021.11.05.467463
https://doi.org/10.1101/2021.11.05.467463
Autor:
Mariana Lozano Gonzalez, Dennis J. Colussi, Tyler Eck, Samantha O. Aylor, Patty J. Lee, Shams Ul Mahmood, Tamara Kreiss, David P. Rotella, Brandon S. Pybus, Purnima Bhanot, Wayne E. Childers, John Gordon, Alison Roth, Rammohan R. Yadav Bheemanaboina, M. L. de Souza, John J. Siekierka
The discovery of new targets for treatment of malaria advanced with the demonstration that orally administered inhibitors of Plasmodium falciparum cGMP-dependent protein kinase (PfPKG) could clear infection in a murine model. This enthusiasm was temp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c612db0e19258f774179b67ca88c35b6
https://doi.org/10.1101/2021.08.24.457553
https://doi.org/10.1101/2021.08.24.457553
Autor:
Rammohan R. Yadav Bheemanaboina, Huimin Cheng, Agnieska Chojnowski, Tyler Eck, David P. Rotella, Ramappa Chakrasali, Sreedhar R. Tummalapalli, John J. Siekierka, Tamara Kreiss, Shams Ul Mahmood
Publikováno v:
RSC Med Chem
The cGMP-dependent protein kinase in Plasmodium falciparum (PfPKG) plays multiple roles in the life cycle of the parasite. As a result, this enzyme is a potential target for new antimalarial agents. Existing inhbitors, while potent and active in mala
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58966d8faee67aec495b00520a3d78da
https://europepmc.org/articles/PMC7536641/
https://europepmc.org/articles/PMC7536641/
Akademický článek
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Autor:
Mauricio F. Erben, Aamer Saeed, Gustavo A. Echeverría, Shams-ul Mahmood, Oscar E. Piro, Zuly Yuliana Delgado Espinosa
Publikováno v:
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Universidad Nacional de La Plata
instacron:UNLP
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
4,7-Dimethyl-2H-chromen-2-one (1) and its novel sulfur analogue 4,7-dimethyl-2H-chromen-2-thione (2) were synthesized and fully characterized by spectroscopic methods and mass spectrometry. The crystal structure of compound 2 has been determined by X
Autor:
Claudiu T. Supuran, Aamer Saeed, Paola Gratteri, Shams-ul Mahmood, Sivia Bua, Alessio Nocentini
Publikováno v:
Bioorganic chemistry. 77
A series of iminothiazolidinone-sulfonamide hybrids ( 2a-k) was synthesized by heterocyclization of sulfanilamide thioureas with methyl bromoacetate and characterized by spectroscopic techniques, mass and elemental analysis. The synthesized derivativ
Publikováno v:
Chemical Biology & Drug Design. 87:434-443
The present work reports the synthesis of several 2-iminothiazoline derivatives of sulfanilamide (3a-j) as inhibitors of jack bean ureases. The title compounds were synthesized by the heterocyclization of sulfanilamide thioureas with propragyl bromid