Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Shams, Kursan"'
Autor:
Mauricio Di Fulvio, Marika Bogdani, Myrian Velasco, Timothy S McMillen, Cecilia Ridaura, Lisa Kelly, Mohammed M Almutairi, Shams Kursan, Abu A Sajib, Marcia Hiriart, Lydia Aguilar-Bryan
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0242749 (2020)
Cystic fibrosis (CF) is due to mutations in the CF-transmembrane conductance regulator (CFTR) and CF-related diabetes (CFRD) is its most common co-morbidity, affecting ~50% of all CF patients, significantly influencing pulmonary function and longevit
Externí odkaz:
https://doaj.org/article/7c1470783e154d3198a3475d640b367f
Autor:
Shams Kursan, Timothy S. McMillen, Pavani Beesetty, Eduardo Dias-Junior, Mohammed M. Almutairi, Abu A. Sajib, J. Ashot Kozak, Lydia Aguilar-Bryan, Mauricio Di Fulvio
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Intracellular chloride concentration ([Cl−]i) in pancreatic β-cells is kept above electrochemical equilibrium due to the predominant functional presence of Cl− loaders such as the Na+K+2Cl− co-transporter 1 (Slc12a2) over Cl−extrude
Externí odkaz:
https://doaj.org/article/d1c00f15f43e41669bcde19b13071f67
Autor:
Shams Kursan, Hayo Castrop, Mohammed M. Almutairi, Mauricio Di Fulvio, Eduardo Dias-Junior, Lisa E. Kelly, Romario Pacheco
Publikováno v:
American Journal of Physiology-Cell Physiology. 317:C843-C856
The Na+K+2Cl− cotransporter-2 ( Nkcc2, Slc12a1) is abundantly expressed in the kidney and its inhibition with the loop-diuretics bumetanide and furosemide has been linked to transient or permanent hyperglycemia in mice and humans. Notably, Slc12a1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb1a46ded32bbec3e03f5479761072ab
https://doi.org/10.1152/ajpcell.00144.2019
https://doi.org/10.1152/ajpcell.00144.2019
Autor:
Marika Bogdani, Timothy S. McMillen, Lisa E. Kelly, Shams Kursan, Lydia Aguilar-Bryan, Marcia Hiriart, Mohammed M. Almutairi, Abu Ashfaqur Sajib, Mauricio Di Fulvio, Myrian Velasco, Cecilia Ridaura
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0242749 (2020)
PLoS ONE
PLoS ONE
Cystic fibrosis (CF) is due to mutations in the CF-transmembrane conductance regulator (CFTR) and CF-related diabetes (CFRD) is its most common co-morbidity, affecting ~50% of all CF patients, significantly influencing pulmonary function and longevit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4c10273ba84ea3ee2421682b31c3899
https://doaj.org/article/7c1470783e154d3198a3475d640b367f
https://doaj.org/article/7c1470783e154d3198a3475d640b367f
Autor:
Lisa, Kelly, Mohammed M, Almutairi, Shams, Kursan, Romario, Pacheco, Eduardo, Dias-Junior, Hayo, Castrop, Mauricio, Di Fulvio
Publikováno v:
Am J Physiol Cell Physiol
The Na(+)K(+)2Cl(−) cotransporter-2 (Nkcc2, Slc12a1) is abundantly expressed in the kidney and its inhibition with the loop-diuretics bumetanide and furosemide has been linked to transient or permanent hyperglycemia in mice and humans. Notably, Slc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2329cd7a10f1ba3c9f8d7b8225bccb64
https://pubmed.ncbi.nlm.nih.gov/31365295
https://pubmed.ncbi.nlm.nih.gov/31365295
Autor:
Gregory P. Boivin, Hayo Castrop, Susan B. Gurley, Lesan K Mattis, Khalid M. Elased, Amma Boakye, Shams Kursan, Mauricio Di Fulvio, Nadja Grobe, Mohammed M. Almutairi, Victor Otaño-Rivera
Publikováno v:
Laboratory Animals. 51:138-146
Genotyping of genetically-engineered mice is necessary for the effective design of breeding strategies and identification of mutant mice. This process relies on the identification of DNA markers introduced into genomic sequences of mice, a task usual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f021273f14c80f41191d97104c795519
https://doi.org/10.1177/0023677216646088
https://doi.org/10.1177/0023677216646088
Autor:
Richa Singh, Mohammed M. Almutairi, Mohamed Y. Almiahoub, Mauricio Di Fulvio, Tomas Garzon-Muvdi, Francisco J. Alvarez-Leefmans, Shams Kursan
Publikováno v:
Frontiers in Cell and Developmental Biology
Na+K+2Cl− co-transporters (NKCCs) effect the electroneutral movement of Na+-K+ and 2Cl− ions across the plasma membrane of vertebrate cells. There are two known NKCC isoforms, NKCC1 (Slc12a2) and NKCC2 (Slc12a1). NKCC1 is a ubiquitously expressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa117b5a7f888ccd7303da3255fe785c
https://doi.org/10.3389/fcell.2016.00150
https://doi.org/10.3389/fcell.2016.00150
Autor:
Mohamed Y. Mahmoud Almiahuob, Mauricio Di Fulvio, Mohammed M. Almutairi, Shams Kursan, Saeed Alshahrani, Lydia Aguilar-Bryan, Eduardo Dias-Junior
Publikováno v:
The Journal of Endocrinology
The products of theSlc12a1andSlc12a2genes, commonly known as Na+-dependent K+2Cl−co-transporters NKCC2 and NKCC1, respectively, are the targets for the diuretic bumetanide. NKCCs are implicated in the regulation of intracellular chloride concentrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1510214366f01f9c74deec1f4e570c82
https://pubmed.ncbi.nlm.nih.gov/26400961
https://pubmed.ncbi.nlm.nih.gov/26400961