Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Shamit, Soneji"'
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
In the adult murine brain, neural stem cells (NSCs) can be found in two main niches: the dentate gyrus (DG) and the subventricular zone (SVZ). In the DG, NSCs produce intermediate progenitors (IPs) that differentiate into excitatory neurons, while pr
Externí odkaz:
https://doaj.org/article/658f183bf70346a79fc7199274d178db
Autor:
Parashar Dhapola, Johan Rodhe, Rasmus Olofzon, Thomas Bonald, Eva Erlandsson, Shamit Soneji, Göran Karlsson
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
As the scale of single-cell genomics experiments grows into the millions, the computational requirements to process this data are beyond the reach of many. Here the authors present Scarf, a modularly designed Python package that makes the analysis wo
Externí odkaz:
https://doaj.org/article/60f7efb619a7412992aebe738a7a79f6
Autor:
Christina T. Jensen, Josefine Åhsberg, Johanna Tingvall-Gustafsson, Rajesh Somasundaram, Stefan Lang, Jonas Ungerbäck, Anna Porwit, Shamit Soneji, Mikael Sigvardsson
Publikováno v:
Haematologica, Vol 108, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/1824c25cb8e9403ba9943e8c2d767111
Autor:
Alexander Mattebo, Taha Sen, Maria Jassinskaja, Kristýna Pimková, Isabel Prieto González-Albo, Abdul Ghani Alattar, Ramprasad Ramakrishnan, Stefan Lang, Marcus Järås, Jenny Hansson, Shamit Soneji, Sofie Singbrant, Emile van den Akker, Johan Flygare
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract The YPEL family genes are highly conserved across a diverse range of eukaryotic organisms and thus potentially involved in essential cellular processes. Ypel4, one of five YPEL family gene orthologs in mouse and human, is highly and specific
Externí odkaz:
https://doaj.org/article/5dc977dcbe104bb4b3fa8157f49bbc12
Autor:
Sarah Warsi, Maria Dahl, Emma M. K. Smith, Anna Rydstrom, Els Mansell, Valgardur Sigurdsson, Julia Sjoberg, Shamit Soneji, Emma Rorby, Kavitha Siva, Tan H. M. Grahn, Yang Liu, Ulrika Blank, Goran Karlsson, Stefan Karlsson
Publikováno v:
Haematologica, Vol 107, Iss 12 (2022)
Even though hematopoietic stem cells (HSC) are characterized by their ability to self-renew and differentiate, they primarily reside in quiescence. Despite the immense importance of this quiescent state, its maintenance and regulation is still incomp
Externí odkaz:
https://doaj.org/article/89aef74030df4d8c80376944eafe6730
Autor:
Stephen Taylor, Shamit Soneji
Publikováno v:
Frontiers in Bioinformatics, Vol 2 (2022)
COVID-19 forced humanity to think about new ways of working globally without physically being present with other people, and eXtended Reality (XR) systems (defined as Virtual Reality, Augmented Reality and Mixed Reality) offer a potentially elegant s
Externí odkaz:
https://doaj.org/article/ed8577e026b04a17a2fa945fc1d3512a
Autor:
Hooi Ching Lim, Shamit Soneji, Róbert Pálmason, Stig Lenhoff, Thomas Laurell, Stefan Scheding
Publikováno v:
Biomarker Research, Vol 9, Iss 1, Pp 1-12 (2021)
Abstract Background Infection and graft-versus-host disease (GvHD) are the major causes for mortality and morbidity of allogeneic hematopoietic stem cell transplantation (allo-HSCT). Plasma-derived extracellular vesicles (EVs) contain disease-related
Externí odkaz:
https://doaj.org/article/110883f232814aeeb3bec62d7f0d3287
Autor:
Shuhei Koide, Valgardur Sigurdsson, Visnja Radulovic, Kiyoka Saito, Zhiqian Zheng, Stefan Lang, Shamit Soneji, Atsushi Iwama, Kenichi Miharada
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103603- (2022)
Summary: Isolation of long-term hematopoietic stem cell (HSC) is possible by utilizing flow cytometry with multiple cell surface markers. However, those cell surface phenotypes do not represent functional HSCs after in vitro culture. Here we show tha
Externí odkaz:
https://doaj.org/article/4ed8a9b81e1147e4ae4d1b2ef49c5c25
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103251- (2021)
Summary: Single-cell RNAseq is a routinely used method to explore heterogeneity within cell populations. Data from these experiments are often visualized using dimension reduction methods such as UMAP and tSNE, where each cell is projected in two or
Externí odkaz:
https://doaj.org/article/7d70ed2f0d934eb0a567f32c61290641
Autor:
Talia Velasco-Hernandez, Shamit Soneji, Isabel Hidalgo, Eva Erlandsson, Jörg Cammenga, David Bryder
Publikováno v:
Stem Cell Reports, Vol 12, Iss 1, Pp 112-121 (2019)
Summary: Relapse of acute myeloid leukemia (AML) remains a significant clinical challenge due to limited therapeutic options and poor prognosis. Leukemic stem cells (LSCs) are the cellular units responsible for relapse in AML, and strategies that tar
Externí odkaz:
https://doaj.org/article/9b5de8aba92f4d12b38fcb0636e34c0c