Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Shamim H Rahman"'
Autor:
Shamim H Rahman, Johannes Kuehle, Christian Reimann, Tafadzwa Mlambo, Jamal Alzubi, Morgan L Maeder, Heimo Riedel, Paul Fisch, Tobias Cantz, Cornelia Rudolph, Claudio Mussolino, J Keith Joung, Axel Schambach, Toni Cathomen
Publikováno v:
PLoS Genetics, Vol 11, Iss 5, p e1005239 (2015)
In vitro disease modeling based on induced pluripotent stem cells (iPSCs) provides a powerful system to study cellular pathophysiology, especially in combination with targeted genome editing and protocols to differentiate iPSCs into affected cell typ
Externí odkaz:
https://doaj.org/article/1408d426c90e4ba8a6c9198e7e74e645
Autor:
Kaweh Pars, Roland Jacobs, Katharina Gellhaus, Sylwia Bobis-Wozowicz, Shamim H. Rahman, Toni Cathomen, Debanjana Chatterjee, Regine Heilbronn
Publikováno v:
Human Gene Therapy; Vol 24
Parameters that regulate or affect the cell cycle or the DNA repair choice between non-homologous end-joining and homology-directed repair (HDR) are excellent targets to enhance therapeutic gene targeting. Here, we have evaluated the impact of five c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e622702168d9a22d420449a68605bb
Publikováno v:
Human Gene Therapy; Vol 22
Zinc-finger nucleases (ZFNs) are a powerful tool that can be used to edit the human genome ad libitum. The technology has experienced remarkable development in the last few years with regard to both the target site specificity and the engineering pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2b6e6b503268bfcc6eadd52f125fa6f
https://europepmc.org/articles/PMC3159524/
https://europepmc.org/articles/PMC3159524/
Publikováno v:
Methods (San Diego, Calif.). 53(4)
Zinc-finger nucleases (ZFNs) are designer nucleases capable of cleaving a prespecified target DNA within complex genomes. ZFNs consist of a non-specific endonuclease domain fused to an engineered DNA-binding domain that tethers the nuclease activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de3d72d0cfda4f52b53c0545ec9186e9
https://pubmed.ncbi.nlm.nih.gov/21185378
https://pubmed.ncbi.nlm.nih.gov/21185378
Autor:
Johannes Kuehle, Morgan L. Maeder, Heimo Riedel, Jamal Alzubi, Tobias Cantz, Claudio Mussolino, Paul Fisch, Christian Reimann, Tafadzwa Mlambo, Axel Schambach, J. Keith Joung, Shamim H. Rahman, Cornelia Rudolph, Toni Cathomen
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 11, Iss 5, p e1005239 (2015)
PLoS Genetics, Vol 11, Iss 5, p e1005239 (2015)
In vitro disease modeling based on induced pluripotent stem cells (iPSCs) provides a powerful system to study cellular pathophysiology, especially in combination with targeted genome editing and protocols to differentiate iPSCs into affected cell typ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b5088cdc8621200ee098c6ac65b56f
https://doi.org/10.1371/journal.pgen.1005239
https://doi.org/10.1371/journal.pgen.1005239
Autor:
Daniel F. Voytas, Jeffry D. Sander, J. Keith Joung, Ronnie J. Winfrey, Toni Cathomen, Jeffrey A. Townsend, Jonathan E. Foley, Shamim H. Rahman, Tatjana I. Cornu, Cherie L. Ramirez, Fengli Fu, Felix Müller-Lerch, David A. Wright
Publikováno v:
Nature Methods. 5:575-575
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1aa034d022ac3556f94332d052544e52
https://doi.org/10.1038/nmeth0608-575a
https://doi.org/10.1038/nmeth0608-575a