Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Shamik Sen"'
Publikováno v:
Translational Oncology, Vol 39, Iss , Pp 101822- (2024)
The glycocalyx—that forms a protective barrier around cells—has been implicated in cancer cell proliferation, survival, and metastasis. However, its role in maintaining the integrity of DNA/nucleus during migration through dense matrices remains
Externí odkaz:
https://doaj.org/article/bb95f10f2b9e4300a712773744913205
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 6 (2022)
ABSTRACT Mimivirus and Marseillevirus infections of Acanthamoeba castellanii, like most other viral infections, induce cytopathic effects (CPE). The details of how they bring about CPE and to what extent and how they modify the host cytoskeletal netw
Externí odkaz:
https://doaj.org/article/4523084f9ea5499a88cf1b3724e55a5e
Publikováno v:
ACS Omega, Vol 5, Iss 33, Pp 21288-21299 (2020)
Externí odkaz:
https://doaj.org/article/4fd5f82225a849908cf11055d0a7d297
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100296- (2021)
Summary: Quantification of nuclear stiffness is challenging for cells encapsulated within a 3D extracellular matrix (ECM). Here, we describe an experimental setup for measuring microenvironment-dependent tuning of nuclear stiffness using an atomic fo
Externí odkaz:
https://doaj.org/article/7bd1b98247544488b51bf0849dcaa4cb
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100310- (2021)
Summary: In vivo cell migration is influenced by soluble factors as well as stiffness. Current in vitro strategies mostly account for one of these two factors to study cell migration. To understand the combinatorial effect of stiffness and chemokines
Externí odkaz:
https://doaj.org/article/dacb72baad8a4778a348713a2b5996a6
Autor:
Arijit Mal, Amirali B. Bukhari, Ram K. Singh, Aastha Kapoor, Amlan Barai, Ishan Deshpande, Tabassum Wadasadawala, Pritha Ray, Shamik Sen, Abhijit De
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
Substantial number of breast cancer (BC) patients undergoing radiation therapy (RT) develop local recurrence over time. During RT therapy, cells can gradually acquire resistance implying adaptive radioresistance. Here we probe the mechanisms underlyi
Externí odkaz:
https://doaj.org/article/b9e10746b91b46fc954afb69f9e70bb7
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 10, p e1008300 (2020)
Large nuclear deformations during migration through confined spaces have been associated with nuclear membrane rupture and DNA damage. However, the stresses associated with nuclear damage remain unclear. Here, using a quasi-static plane strain finite
Externí odkaz:
https://doaj.org/article/1cd5204ab28346f591448bb63094f2f8
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Cancer invasion through dense extracellular matrices (ECMs) is mediated by matrix metalloproteinases (MMPs) which degrade the ECM thereby creating paths for migration. However, how this degradation influences the phenotype of cancer cells is
Externí odkaz:
https://doaj.org/article/d3662dc961f54566b67919e8a216311e
Autor:
Manalee Vishnu Surve, Anjali Anil, Kshama Ganesh Kamath, Smita Bhutda, Lakshmi Kavitha Sthanam, Arpan Pradhan, Rohit Srivastava, Bhakti Basu, Suryendu Dutta, Shamik Sen, Deepak Modi, Anirban Banerjee
Publikováno v:
PLoS Pathogens, Vol 12, Iss 9, p e1005816 (2016)
Infection of the genitourinary tract with Group B Streptococcus (GBS), an opportunistic gram positive pathogen, is associated with premature rupture of amniotic membrane and preterm birth. In this work, we demonstrate that GBS produces membrane vesic
Externí odkaz:
https://doaj.org/article/7013f127c93047098361fe3d21117b79
Autor:
S S Soumya, Animesh Gupta, Andrea Cugno, Luca Deseri, Kaushik Dayal, Dibyendu Das, Shamik Sen, Mandar M Inamdar
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 12, p e1004670 (2015)
Coherent angular rotation of epithelial cells is thought to contribute to many vital physiological processes including tissue morphogenesis and glandular formation. However, factors regulating this motion, and the implications of this motion if pertu
Externí odkaz:
https://doaj.org/article/b2b3399a8c8d41faaa82a71ac4694aea