Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Shami Elie Gabriel"'
Publikováno v:
International Journal of Pharmaceutics. 38:199-209
Two prodrugs of nalbuphine (1), the acetylsalicylate (2) and anthranilate (3) esters, were prepared with the objective of increasing oral nalbuphine bioavailability. Hydrolysis rates in rat, monkey, dog, and human plasma, human whole blood, and rat a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ccb7d81dc1738d013164a697ae50814
https://doi.org/10.1016/0378-5173(87)90115-3
https://doi.org/10.1016/0378-5173(87)90115-3
Publikováno v:
Journal of Pharmaceutical Sciences. 62:293-297
The effect of flow rates on dissolution rates using a continuous flow, column-type apparatus was determined. The flow method of agitation is compared to three other types used with the static beaker procedure. The advantages of the column-type appara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a74db814921824eff3e1714a6620b8f0
https://doi.org/10.1002/jps.2600620225
https://doi.org/10.1002/jps.2600620225
Publikováno v:
Journal of Pharmaceutical Sciences. 76:356-358
In an effort to improve the oral bioavailability of naltrexone [17-(cyclopropylmethyl)-4,5 alpha-epoxy-3,14-dihydroxymorphinan-6-one;1], a number of prodrug esters on the 3-hydroxyl group were prepared: the anthranilate (2), acetylsalicylate (3), ben
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::614091d14a0f721cfa6d663c4572ac67
https://doi.org/10.1002/jps.2600760503
https://doi.org/10.1002/jps.2600760503
Publikováno v:
Journal of Pharmaceutical Sciences. 62:1283-1285
A nonsolvolytic (solid-state) reaction between aspirin and homatropine, yielding acetylhomatropine and free salicylic acid, is reported. A GC assay for homatropine is described. In the presence of excess aspirin, the kinetics are pseudo first order w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::990cfd9e142e9b4d68faab94e59d59ff
https://doi.org/10.1002/jps.2600620810
https://doi.org/10.1002/jps.2600620810
Publikováno v:
Journal of pharmaceutical sciences. 70(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abc670e2dc92d33f3deaf3b6315c053e
https://pubmed.ncbi.nlm.nih.gov/6166740
https://pubmed.ncbi.nlm.nih.gov/6166740
Autor:
Shami, Elie Gabriel
Thesis (Ph. D.)--University of Wisconsin--Madison, 1964.
Typescript. Vita. Abstracted in Dissertation abstracts, v. 25 (1964) no. 6, p. 3520. eContent provider-neutral record in process. Description based on print version record. Includes biblio
Typescript. Vita. Abstracted in Dissertation abstracts, v. 25 (1964) no. 6, p. 3520. eContent provider-neutral record in process. Description based on print version record. Includes biblio
Externí odkaz:
http://catalog.hathitrust.org/api/volumes/oclc/48105174.html
Publikováno v:
Journal of pharmaceutical sciences. 62(8)
A simplified method for determining the chemical stability of drug substances in pharmaceutical suspensions is described. The applicable theory is discussed, and a suitable example from the literature is presented. The value of the method is confirme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cc84bbbc17b1c5870b0676518f09a11
https://pubmed.ncbi.nlm.nih.gov/4725189
https://pubmed.ncbi.nlm.nih.gov/4725189
Publikováno v:
Journal of pharmaceutical sciences. 62(4)
Preformulation studies on molindone hydrochloride, a dihydroindolone tranquilizer, are described. A TLC assay is outlined, degradation products are identified, and results of stability studies are presented. The dissociation constant is estimated usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ce0b1f333587e55f523bff67ef6eaa8
https://pubmed.ncbi.nlm.nih.gov/4698984
https://pubmed.ncbi.nlm.nih.gov/4698984
Publikováno v:
Journal of pharmaceutical sciences. 61(12)
A modified, continuous flow, column-type dissolution apparatus, using commercially available components, is described. Two different size dissolution chambers are compared. The system is employed to evaluate experimental and commercial tablets of iso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd3b23b8220fcb88865dd87c72ab41ea
https://pubmed.ncbi.nlm.nih.gov/4638111
https://pubmed.ncbi.nlm.nih.gov/4638111