Molecular mimicry sweetens the deal for MANagement of host mRNA translation and stress responses by Legionella pneumophila.

Autor: Shames SR; Department of Microbiology & Molecular Genetics, Michigan State University, East Lansing, MI 48824, USA. Electronic address: shames@msu.edu.

Publikováno v: Molecular cell [Mol Cell] 2024 Jan 04; Vol. 84 (1), pp. 14-16.

Effector-mediated subversion of proteasome activator (PA)28αβ enhances host defense against Legionella pneumophila under inflammatory and oxidative stress conditions.

Autor: Ngwaga T; Division of Biology, Kansas State University, Manhattan, Kansas, United States of America., Chauhan D; Division of Biology, Kansas State University, Manhattan, Kansas, United States of America., Salberg AG; Division of Biology, Kansas State University, Manhattan, Kansas, United States of America., Shames SR; Division of Biology, Kansas State University, Manhattan, Kansas, United States of America.; Department of Microbiology & Molecular Genetics, Michigan State University, East Lansing, Michigan, United States of America.

Publikováno v: PLoS pathogens [PLoS Pathog] 2023 Jun 22; Vol. 19 (6), pp. e1011473. Date of Electronic Publication: 2023 Jun 22 (Print Publication: 2023).

Intrabacterial Regulation of a Cytotoxic Effector by Its Cognate Metaeffector Promotes Legionella pneumophila Virulence.

Autor: Chauhan D; Division of Biology, Kansas State University, Manhattan, Kansas, USA., Joseph AM; Division of Biology, Kansas State University, Manhattan, Kansas, USA., Shames SR; Division of Biology, Kansas State University, Manhattan, Kansas, USA.; Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, USA.

Publikováno v: MSphere [mSphere] 2023 Feb 21; Vol. 8 (1), pp. e0055222. Date of Electronic Publication: 2023 Jan 04.

Mechanisms of Effector-Mediated Immunity Revealed by the Accidental Human Pathogen Legionella pneumophila .

Autor: Ngwaga T; Division of Biology, Kansas State University, Manhattan, KS, United States., Chauhan D; Division of Biology, Kansas State University, Manhattan, KS, United States., Shames SR; Division of Biology, Kansas State University, Manhattan, KS, United States.

Publikováno v: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2021 Feb 03; Vol. 10, pp. 593823. Date of Electronic Publication: 2021 Feb 03 (Print Publication: 2020).

The Legionella pneumophila Metaeffector Lpg2505 (MesI) Regulates SidI-Mediated Translation Inhibition and Novel Glycosyl Hydrolase Activity.

Autor: Joseph AM; Division of Biology, Kansas State University, Manhattan, Kansas, USA., Pohl AE; Division of Biology, Kansas State University, Manhattan, Kansas, USA., Ball TJ; Division of Biology, Kansas State University, Manhattan, Kansas, USA., Abram TG; Department of Biochemistry and Molecular Biophysics, Kansas State University, Manhattan, Kansas, USA., Johnson DK; Molecular Graphics and Modeling Laboratory, Computational Chemical Biology Core, University of Kansas, Lawrence, Kansas, USA., Geisbrecht BV; Department of Biochemistry and Molecular Biophysics, Kansas State University, Manhattan, Kansas, USA., Shames SR; Division of Biology, Kansas State University, Manhattan, Kansas, USA sshames@ksu.edu.

Publikováno v: Infection and immunity [Infect Immun] 2020 Apr 20; Vol. 88 (5). Date of Electronic Publication: 2020 Apr 20 (Print Publication: 2020).