Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Shambhu G. Aralaguppe"'
Autor:
Shambhu G. Aralaguppe, Anoop T. Ambikan, Manickam Ashokkumar, Milner M. Kumar, Luke Elizabeth Hanna, Wondwossen Amogne, Anders Sönnerborg, Ujjwal Neogi
Publikováno v:
Viruses, Vol 11, Iss 9, p 806 (2019)
The detection of drug resistance mutations (DRMs) in minor viral populations is of potential clinical importance. However, sophisticated computational infrastructure and competence for analysis of high-throughput sequencing (HTS) data lack at most di
Externí odkaz:
https://doaj.org/article/eff71ce6835a4bd59badf27246ae4271
Autor:
Anders Sönnerborg, Aman Russom, Ujjwal Neogi, Shambhu G Aralaguppe, Amin Kazemzadeh, Wang Zhang, Indradumna Banerjee, Noa Lapins
Publikováno v:
Lab on a Chip. 19:1657-1664
Nucleic acid amplification methods are increasingly being used to detect trace quantities of DNA in samples for various diagnostic applications. However, quantifying the amount of DNA from such methods often requires time consuming purification, wash
Autor:
Sezanur Rahman, Mustafizur Rahman, Golam Sarwar, Safiullah Sarker, Shambhu G Aralaguppe, Sharful Islam Khan
Publikováno v:
Journal of medical virologyREFERENCES. 94(2)
In Bangladesh, antiretroviral therapy (ART) is provided without screening drug resistance-associated mutations (DRM) among people living with HIV, while DRM might emerge and transmit to the newly infected individual. The present study was aimed to id
High-throughput sequencing reveals a high prevalence of pretreatment HIV-1 drug resistance in Sweden
Autor:
Ujjwal Neogi, Shambhu G Aralaguppe, Aylin Yilmaz, Johanna Brännström, Emmi Andersson, Anders Sönnerborg, Jan Albert, Anoop T. Ambikan
Publikováno v:
AIDS
Objectives HIV-1 pretreatment drug resistance (PDR) is a global concern. Our aim was to evaluate high-throughput sequencing (HTS) for HIV-1 resistance testing and describe PDR in Sweden, where 75% of diagnosed individuals are foreign-born. Design Cro
Publikováno v:
Virus Evolution
The Swedish HIV-1 epidemic is characterized by a high diversity in HIV subtypes and recombinants as a result of migration. To study the time from infection through viral diversification, transmission patterns, and drug resistance in minor quasispecie
Autor:
Anders Sönnerborg, Shambhu G Aralaguppe, Anoop T. Ambikan, Milner M. Kumar, Ujjwal Neogi, Manickam Ashokkumar, Wondwossen Amogne, Luke Elizabeth Hanna
Publikováno v:
Viruses
Viruses, Vol 11, Iss 9, p 806 (2019)
Volume 11
Issue 9
Viruses, Vol 11, Iss 9, p 806 (2019)
Volume 11
Issue 9
The detection of drug resistance mutations (DRMs) in minor viral populations is of potential clinical importance. However, sophisticated computational infrastructure and competence for analysis of high-throughput sequencing (HTS) data lack at most di
Autor:
Ashokkumar Manickam, Shambhu G Aralaguppe, Anoop T. Ambikan, Ujjwal Neogi, Milner M. Kumar, Anders Sönnerborg, Abu Bakar Siddik, Dhinoth K. Bangaruswamy, Sunjay Jude Fernandes, Luke Elizabeth Hanna, Wondwossen Amogne
Publikováno v:
Journal of Virological Methods. 236:98-104
Analysing the HIV-1 near full-length genome (HIV-NFLG) facilitates new understanding into the diversity of virus population dynamics at individual or population level. In this study we developed a simple but high-throughput next generation sequencing
Autor:
Stefan G. Sarafianos, Dane Winner, Ujjwal Neogi, Miguel E. Quiñones-Mateu, Shambhu G Aralaguppe, Kamalendra Singh, Anders Sönnerborg
Publikováno v:
Journal of Medical Virology. 89:106-111
BACKGROUND A lower virulence of HIV-1 subtype C (HIV-1C) is suggested to be related to the global dominance of HIV-1C. In this observational study, combining in vivo (clinical monitoring) and in vitro (genotypic, biochemical, and phenotypic assays),
Autor:
Srikanth Tripathy, Ujjwal Neogi, Shambhu G Aralaguppe, Luke Elizabeth Hanna, Manickam Ashokkumar
Adequate information on the precise molecular and biological composition of the viral strains that establish HIV infection in the human host will provide effective means of immunization against HIV infection. In an attempt to identify the transmitted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f2640f832f54e8c8573f87f441087b0
https://europepmc.org/articles/PMC5899188/
https://europepmc.org/articles/PMC5899188/
Autor:
Kamalendra Singh, Duncan T Njenda, Anders Sönnerborg, Shambhu G Aralaguppe, Rohit Rao, Ujjwal Neogi, Stefan G. Sarafianos
Publikováno v:
The Journal of antimicrobial chemotherapy. 73(10)
OBJECTIVES: 4′-Ethnyl-2′-fluoro-2′-deoxyadenosine (EFdA) is a novel translocation-defective reverse transcriptase inhibitor. We investigated the virological and biochemical inhibitory potentials of EFdA against a broad spectrum of subtype-speci