Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Shambhavi, Bhagwat"'
Autor:
Dhivya Sridaran, Surbhi Chouhan, Kiran Mahajan, Arun Renganathan, Cody Weimholt, Shambhavi Bhagwat, Melissa Reimers, Eric H. Kim, Manish K. Thakur, Muhammad A. Saeed, Russell K. Pachynski, Markus A. Seeliger, W. Todd Miller, Felix Y. Feng, Nupam P. Mahajan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Immune checkpoint blockade is showing promise in cancer immune therapy, but many solid tumours are resistant. Authors here identify a pathway in T cells that leads to increased activity of C-terminal Src kinase, a negative regulator of T cell activit
Externí odkaz:
https://doaj.org/article/7caeec47da1c4212a9d6e0933f20b457
Autor:
Dhivya, Sridaran, Surbhi, Chouhan, Kiran, Mahajan, Arun, Renganathan, Cody, Weimholt, Shambhavi, Bhagwat, Melissa, Reimers, Eric H, Kim, Manish K, Thakur, Muhammad A, Saeed, Russell K, Pachynski, Markus A, Seeliger, W Todd, Miller, Felix Y, Feng, Nupam P, Mahajan
Publikováno v:
Nature communications. 13(1)
Solid tumours are highly refractory to immune checkpoint blockade (ICB) therapies due to the functional impairment of effector T cells and their inefficient trafficking to tumours. T-cell activation is negatively regulated by C-terminal Src kinase (C
Autor:
Shambhavi Bhagwat, Matthew L. Goodwin
Publikováno v:
The Spine Journal. 22:S128
Publikováno v:
The Spine Journal. 22:S105
Autor:
Pavani Malla, Nupam P. Mahajan, Jeffery Weber, Shambhavi Bhagwat, Shari Pilon-Thomas, Vasundhara Sharma, Kiran Mahajan, Jongphil Kim, Amod A. Sarnaik
Publikováno v:
Oncotarget. 8:106352-106368
Epigenetic signaling networks dynamically regulate gene expression to maintain cellular homeostasis. Previously, we uncovered that WEE1 phosphorylates histone H2B at tyrosine 37 (pY37-H2B) to negatively regulate global histone transcriptional output.
Autor:
Nupam P, Mahajan, Pavani, Malla, Shambhavi, Bhagwat, Vasundhara, Sharma, Amod, Sarnaik, Jongphil, Kim, Shari, Pilon-Thomas, Jeffery, Weber, Kiran, Mahajan
Publikováno v:
Oncotarget
Epigenetic signaling networks dynamically regulate gene expression to maintain cellular homeostasis. Previously, we uncovered that WEE1 phosphorylates histone H2B at tyrosine 37 (pY37-H2B) to negatively regulate global histone transcriptional output.