Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Shamaruh Mirza"'
Autor:
Angela F. Dulhunty, Linwei Li, Amy D. Hanna, Nuur Aa Ghazali, Nicole A. Beard, Elize Wium, Shamaruh Mirza, Sadik Talukder
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 39:477-484
SUMMARY The contractile function of the heart requires the release of Ca(2+) from intracellular Ca(2+) stores in the sarcoplasmic reticulum (SR) of cardiac muscle cells. The efficacy of Ca(2+) release depends on the amount of Ca(2+) loaded into the C
Autor:
Han-Shen Tae, Lan Wei, Philip G. Board, Shamaruh Mirza, Esther M. Gallant, Robert T. Dirksen, Marco G. Casarotto, Angela F. Dulhunty, Hermia Willemse
Publikováno v:
Channels. 5:148-160
The second of three SPRY domains (SPRY2, S1085 -V1208) located in the skeletal muscle ryanodine receptor (RyR1) is contained within regions of RyR1 that influence EC coupling and bind to imperatoxin A, a toxin probe of RyR1 channel gating. We examine
Autor:
Bin Wen, James M. Murphy, Jin Dai, Jinglong Chen, Cameron L. Ewens, Shamaruh Mirza, Ian G. Young
Publikováno v:
Journal of Biological Chemistry. 285:22370-22381
The cytokine interleukin-3 (IL-3) is a critical regulator of inflammation and immune responses in mammals. IL-3 exerts its effects on target cells via receptors comprising an IL-3-specific alpha-subunit and common beta-subunit (beta c; shared with IL
Autor:
Andrew A. Walker, James M. Murphy, Sally C. Ford, Jinglong Chen, Jane E. Olsen, Shamaruh Mirza, Ian G. Young
Publikováno v:
Journal of Biological Chemistry. 284:5763-5773
Interleukin-3 (IL-3) promotes both self-renewal and differentiation of early multipotential progenitors and is involved in inducible hematopoiesis in response to infections. Here we report new insights into these processes with the identification of
Autor:
Ian G. Young, Jinglong Chen, Shamaruh Mirza, James M. Murphy, Jane E. Olsen, Tatiana A. Soboleva, Sally C. Ford
Publikováno v:
Cytokine. 42:234-242
Granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin (IL)-3 and IL-5 are related cytokines that play key roles in regulating the differentiation, proliferation, survival and activation of myeloid blood cells. The cell surface recept
Autor:
Nicole A. Beard, Francesco Zorzato, Angela F. Dulhunty, Shamaruh Mirza, Dan Liu, Linwei Li, Chris Thekkedam, Esther M. Gallant, Spencer J. Richardson, Suzy M. Pace
Publikováno v:
Journal of Cell Science.
Junctin, a non-catalytic splice variant encoded by the aspartate-β-hydroxylase ( Asph ) gene, is inserted into the membrane of the sarcoplasmic reticulum (SR) Ca 2+ store where it modifies Ca 2+ signalling in the heart and skeletal muscle through it
Publikováno v:
Biophysical Journal. 104(2)
Junctin is an intrinsic sarcoplasmic reticulum (SR) membrane protein in cardiac and skeletal muscle. The bulk of the protein is within the lumen of the SR where it binds to ryanodine receptor (RyR) calcium release channels and regulates Ca2+ release
The cytokines, interleukin-3 (IL-3), interleukin-5 (IL-5), and granulocyte-macrophage colony-stimulating factor (GM-CSF), exhibit overlapping activities in the regulation of hematopoietic cells. In humans, the common beta (betac) receptor is shared b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a6158ee6993457fe401ffaf93dc89e2
https://europepmc.org/articles/PMC2915712/
https://europepmc.org/articles/PMC2915712/
Publikováno v:
The Biochemical journal. 426(3)
GM-CSF (granulocyte/macrophage colony-stimulating factor) is an important mediator of inducible haemopoiesis and inflammation, and has a critical role in the function of alveolar macrophages. Its clinical applications include the mobilization of haem
Publikováno v:
Cytokine. 48:130