Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Shama Bhatia"'
Publikováno v:
Cells, Vol 12, Iss 18, p 2308 (2023)
Oxoguanine glycosylase 1 (OGG1) is widely known to repair the reactive oxygen species (ROS)-initiated DNA lesion 8-oxoguanine (8-oxoG), and more recently was shown to act as an epigenetic modifier. We have previously shown that saline-exposed Ogg1
Externí odkaz:
https://doaj.org/article/319c4f85c36f4c92ab887426a415a1e1
Autor:
Margaret M. Loniewska, Anmol Gupta, Shama Bhatia, Isabel MacKay-Clackett, Zhengping Jia, Peter G. Wells
Publikováno v:
Redox Biology, Vol 28, Iss , Pp - (2020)
Mice deficient in glucose-6-phosphate dehydrogenase (G6PD) cannot replenish the cellular antioxidant glutathione, which detoxifies neurodegenerative reactive oxygen species (ROS). To determine the functional consequences of G6PD deficiency, young and
Externí odkaz:
https://doaj.org/article/f9921432ed9442a392ef003bb94f9c58
Publikováno v:
Toxicology Letters. 356:121-131
Oxoguanine glycosylase 1 (OGG1) is both a DNA repair enzyme and an epigenetic modifier. We assessed behavioural abnormalities in OGG1-deficient progeny exposed once in utero to a low dose of ethanol (EtOH) and treated postnatally with a global histon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f2e9d9510b5bf824518bb24f1ce4eaf
https://doi.org/10.1016/j.toxlet.2021.12.010
https://doi.org/10.1016/j.toxlet.2021.12.010
Publikováno v:
Toxicological Sciences. 187:93-111
Oxoguanine glycosylase 1 (OGG1) repairs the predominant reactive oxygen species-initiated DNA lesion 8-oxoguanine. Human OGG1 polymorphisms resulting in reduced DNA repair associate with an increased risk for disorders like cancer and diabetes, but t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eac572db80206efc55deb5b97464e143
https://doi.org/10.1093/toxsci/kfac003
https://doi.org/10.1093/toxsci/kfac003
Autor:
Zhengping Jia, Isabel Mackay-Clackett, Anmol Gupta, Peter G. Wells, Shama Bhatia, Margaret M. Loniewska
Publikováno v:
Redox Biology, Vol 28, Iss, Pp-(2020)
Redox Biology
Redox Biology
Mice deficient in glucose-6-phosphate dehydrogenase (G6PD) cannot replenish the cellular antioxidant glutathione, which detoxifies neurodegenerative reactive oxygen species (ROS). To determine the functional consequences of G6PD deficiency, young and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f00371dac5eed81c81c70162c45ca35
http://www.sciencedirect.com/science/article/pii/S2213231719308146
http://www.sciencedirect.com/science/article/pii/S2213231719308146
Autor:
Shama, Bhatia, Peter G, Wells
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1965
The reactive oxygen species (ROS)-initiated DNA lesion 8-oxoguanine (8-oxoG) is commonly used as a biomarker to measure oxidative stress levels in tissue samples from animals and humans. This lesion also can play a pathogenic role in cancer, birth de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f7edd1a701daaf502fcef2d3f9d32a97
https://pubmed.ncbi.nlm.nih.gov/31069685
https://pubmed.ncbi.nlm.nih.gov/31069685
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1965
Chromatin immunoprecipitation (ChIP) is widely used to measure protein-DNA interactions. This protocol outlines a ChIP method used to identify the association of a protein or protein modification (such as a specific histone modification-methylation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6dd887eb4d0d225d5c2f876a2fc6a27d
https://pubmed.ncbi.nlm.nih.gov/31069688
https://pubmed.ncbi.nlm.nih.gov/31069688
Autor:
Peter G. Wells, Shama Bhatia
Publikováno v:
Methods in Molecular Biology ISBN: 9781493991815
The reactive oxygen species (ROS)-initiated DNA lesion 8-oxoguanine (8-oxoG) is commonly used as a biomarker to measure oxidative stress levels in tissue samples from animals and humans. This lesion also can play a pathogenic role in cancer, birth de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b4d2d9f26343c994562a80738bcc4fc
https://doi.org/10.1007/978-1-4939-9182-2_22
https://doi.org/10.1007/978-1-4939-9182-2_22
Publikováno v:
Methods in Molecular Biology ISBN: 9781493991815
Chromatin immunoprecipitation (ChIP) is widely used to measure protein-DNA interactions. This protocol outlines a ChIP method used to identify the association of a protein or protein modification (such as a specific histone modification-methylation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bd4efe76a6624263d4d7182d04103f7
https://doi.org/10.1007/978-1-4939-9182-2_25
https://doi.org/10.1007/978-1-4939-9182-2_25
Publikováno v:
Birth Defects Research Part C: Embryo Today: Reviews. 108:108-130
In utero exposure of mouse progeny to alcohol (ethanol, EtOH) and methamphetamine (METH) causes substantial postnatal neurodevelopmental deficits. One emerging pathogenic mechanism underlying these deficits involves fetal brain production of reactive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d9a5c0814f2c40367d692cae8e1d355
https://doi.org/10.1002/bdrc.21134
https://doi.org/10.1002/bdrc.21134