Výsledky vyhledávání - "Shalton M. Mwaringa"

Akademický článek

Presence, persistence and effects of pre-treatment HIV-1 drug resistance variants detected using next generation sequencing: A Retrospective longitudinal study from rural coastal Kenya.

Autor: Amin S Hassan, David F Bibby, Shalton M Mwaringa, Clara A Agutu, Kennedy K Ndirangu, Eduard J Sanders, Patricia A Cane, Jean L Mbisa, James A Berkley

Publikováno v: PLoS ONE, Vol 14, Iss 2, p e0210559 (2019)

BackgroundThe epidemiology of HIV-1 drug resistance (HIVDR) determined by Sanger capillary sequencing, has been widely studied. However, much less is known about HIVDR detected using next generation sequencing (NGS) methods. We aimed to determine the

Externí odkaz: https://doaj.org/article/eeaac246b40b46288f0ceef1a030a324

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Childhood mortality during and after acute illness in sub-Saharan Africa and South Asia - The CHAIN cohort study

Autor: Julie Jemutai, Christine Manyasi, Shamsun Nahar Shaima, Johnstone Thitiri, Mohammod Jobayer Chisti, Daniella Brals, Syera Banu, Dilruba Ahmed, Peace Aber, Ali Faisal Saleem, Kirkby D Tickell, Sassy Molyneux, Lubaba Shahrin, Abu Sadat Mohammad Sayeem Bin Shahid, Abdoulaye Hama Diallo, Priya Sukhtankar, Tahmeed Ahmed, Syed Asad Ali, Blaise Siezanga Gnoumou, Issaka Ouedraogo, Benson Singa, Moses Mburu, Syeda Momena Afsana, Molly Timbwa, Dinesh Mondal, Philliness Prisca Harawa, Narshion Ngao, Christine J. McGrath, Md. Iqbal Hossain, Roseline Maimouna Bamouni, Catherine Achieng Otieno, Zaubina Kazi, Christina Lancioni, Caroline Tigoi, Christopher Lwanga, John Mukisa, Shalton M. Mwaringa, Judd L. Walson, Christopher Maronga, Emmie Mbale, MacPherson Mallewa, Ezekiel Mupere, James A. Berkley, Joseph D. Carreon, Robert H. J. Bandsma, Chris Odhiambo Oduol, Gazi Md. Salauddin Mamun, Emmanuel Chimezi, Dorothy I. Mangale, Wieger Voskuijl, Ali Fazal Khan, Jenala Njirammadzi, Moses Ngari, Celine Bourdon, Donna M. Denno

ObjectivesMortality during acute illness among children in low- and middle-income settings remain unacceptably high and there is increasing recognition of the importance of post-discharge mortality. A comprehensive understanding of pathways underlyin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::69dcb3acc18f1061fe36bd94fcc90e82
https://doi.org/10.1101/2021.11.24.21266806

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Presence, persistence and effects of pre-treatment HIV-1 drug resistance variants detected using next generation sequencing: A Retrospective longitudinal study from rural coastal Kenya

Autor: Kennedy K Ndirangu, Eduard J. Sanders, Shalton M. Mwaringa, James A. Berkley, Jean L. Mbisa, Amin S. Hassan, Clara A. Agutu, Patricia A. Cane, David F. Bibby

Publikováno v: PLoS ONE, Vol 14, Iss 2, p e0210559 (2019)
PLoS ONE

Background The epidemiology of HIV-1 drug resistance (HIVDR) determined by Sanger capillary sequencing, has been widely studied. However, much less is known about HIVDR detected using next generation sequencing (NGS) methods. We aimed to determine th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbcec06539e8ab4d1be28f229fc8e66c
https://doaj.org/article/eeaac246b40b46288f0ceef1a030a324

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HIV-1 virologic failure and acquired drug resistance among first-line antiretroviral experienced adults at a rural HIV clinic in coastal Kenya: a cross-sectional study

Autor: Tobias F. Rinke de Wit, Shalton M. Mwaringa, Amin S. Hassan, Clare A. Obonyo, Patricia A. Cane, Eduard J. Sanders, James A. Berkley, Helen M. Nabwera

Publikováno v: AIDS research and therapy, 11(1). BioMed Central
AIDS Research and Therapy

BACKGROUND: An increasing number of people on antiretroviral therapy (ART) in sub-Saharan Africa has led to declines in HIV related morbidity and mortality. However, virologic failure (VF) and acquired drug resistance (ADR) may negatively affect thes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c87ead1abf0bcbc81ea297cdcc99f91
https://ora.ox.ac.uk/objects/uuid:774f19b5-408b-43e6-b1ac-dc7d85da5a0f

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Control of viremia enables acquisition of resting memory B cells with age and normalization of activated B cell phenotypes in HIV-infected children

Autor: James A. Berkley, Shalton M. Mwaringa, Britta C. Urban, Gladys Macharia, Amin S. Hassan, Eunice Nduati, Daniel M. Muema, Greg Fegan

Publikováno v: The Journal of Immunology Author Choice

HIV affects the function of all lymphocyte populations, including B cells. Phenotypic and functional defects of B cells in HIV-infected adults have been well characterized, but defects in children have not been studied to the same extent. We determin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5115fa2f12a4140fb7a711915a926f19
http://ora.ox.ac.uk/objects/uuid:5ee018ed-ff85-4a0a-8970-f0fc1c994894

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Incidence and predictors of attrition from antiretroviral care among adults in a rural HIV clinic in Coastal Kenya: a retrospective cohort study

Autor: Eduard J. Sanders, Tobias F. Rinke de Wit, Shalton M. Mwaringa, James A. Berkley, Kennedy K Ndirangu, Amin S. Hassan

Publikováno v: BMC public health, 15(1). BioMed Central
BMC Public Health

Background: Scale up of antiretroviral therapy (ART) has led to substantial declines in HIV related morbidity and mortality. However, attrition from ART care remains a major public health concern and has been identified as one of the key reportable i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc57eeabcca4c581f87102af9f81c932
https://pure.amc.nl/en/publications/incidence-and-predictors-of-attrition-from-antiretroviral-care-among-adults-in-a-rural-hiv-clinic-in-coastal-kenya-a-retrospective-cohort-study(5ba2ab90-d910-4519-aaea-35a3fb16d721).html

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Low prevalence of transmitted HIV type 1 drug resistance among antiretroviral-naive adults in a rural HIV clinic in Kenya

Autor: Clare A. Obonyo, Tobias F. Rinke de Wit, Amin S. Hassan, Shalton M. Mwaringa, James A. Berkley, Patricia A. Cane, Helen M. Nabwera, Eduard J. Sanders

Publikováno v: AIDS research and human retroviruses, 29(1), 129-135. Mary Ann Liebert Inc.

Low levels of HIV-1 transmitted drug resistance (TDR) have previously been reported from many parts of sub-Saharan Africa (sSA). However, recent data, mostly from urban settings, suggest an increase in the prevalence of HIV-1 TDR. Our objective was t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deca6641b37149400a662a85d13ec63a
http://ora.ox.ac.uk/objects/uuid:924363fc-98d6-4221-ac89-b693e1b859fe

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Audit of outcomes of early initiation of antiretroviral therapy in children admitted to the paediatric wards at Kilifi district hospital, Kenya

Autor: James A. Berkley, Helen M. Nabwera, Shalton M. Mwaringa, R Kimutai

Publikováno v: Europe PubMed Central
Journal of the International AIDS Society

Background: Studies in adults suggest that early initiation of anti-retroviral therapy (ART), during treatment of those presenting with opportunistic infections, results in better outcomes than deferred treatment. However, data on the effects of earl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76f847ff485fd1d497d23120048bdb68
http://europepmc.org/abstract/PMC/PMC3112934

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