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pro vyhledávání: '"Shally Margolis"'
Autor:
Michael B. O'Connor, Rebecca Plessel, Michael Burel, Lydia Grmai, Salvador C Herrera, Shally Margolis, Marc Amoyel, Diego Sainz de la Maza, Erika A. Bach
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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© 2021 The Authors
Aging causes stem cell dysfunction as a result of extrinsic and intrinsic changes. Decreased function of the stem cell niche is an important contributor to this dysfunction. We use the Drosophila testis to investigate what fa
Aging causes stem cell dysfunction as a result of extrinsic and intrinsic changes. Decreased function of the stem cell niche is an important contributor to this dysfunction. We use the Drosophila testis to investigate what fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dadd5d6b358a3b19117b045af93d062c
http://hdl.handle.net/10261/260229
http://hdl.handle.net/10261/260229
Publikováno v:
Amoyel, M, Hillion, K-H, Margolis, S R & Bach, E A 2016, ' Somatic stem cell differentiation is regulated by PI3K/Tor signaling in response to local cues ', Development (Cambridge), vol. 143, no. 21, pp. 3914-3925 . https://doi.org/10.1242/dev.139782
Stem cells reside in niches that provide signals to maintain self-renewal, and differentiation is viewed as a passive process that depends on losing access to these signals. Here we demonstrate that differentiation of somatic cyst stem cells (CySCs)