Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Shalley K. Gupta"'
Publikováno v:
Journal of Leukocyte Biology. 70:431-438
The CXC chemokine SDF-1 and its receptor CXCR4 mediate myelopoiesis, presumably by regulating the homing of hematopoietic progenitor cells. We used the inducible HL-60 cell line as a model system for comparative analysis of CXCR4 expression during di
Publikováno v:
Inflammation. 25:293-300
Stromal cell derived factor-1 (SDF-1) is a member of the non-ELR subfamily of CXC chemokines. SDF-1 and its receptor, CXCR4, are essential for cardiogenesis, hematopoiesis, and vasculogenesis during embryonic development, in addition to involvement i
Publikováno v:
IUBMB Life (International Union of Biochemistry and Molecular Biology: Life). 50:51-56
The stimulatory mAb F11 binds two platelet membrane proteins of 32 and 35 kDa and causes activation of platelets when cross-linked with the FcgammaRII receptor. We used bioinformatics to identify expressed sequence tags from libraries of cytokine-sti
Publikováno v:
The Journal of Immunology. 163:2368-2372
Human CXCR4 is a specific receptor for the CXC chemokine stromal cell-derived factor-1 (SDF-1) and a coreceptor for T cell line tropic strains of HIV-1. Genetic knockouts of CXCR4 and SDF-1 have delineated their critical role during embryonic cardiog
Publikováno v:
Journal of Leukocyte Biology. 66:135-143
Chemoattraction of monocytes by the CXC chemokine stromal cell-derived factor-1α (SDF-1α) and its receptor CXCR4 may be involved in vascular diseases like atherosclerosis. We studied the regulation of CXCR4 transcription and SDF-1-induced functiona
Autor:
Kodandaram Pillarisetti, Shalley K. Gupta, Eliot H. Ohlstein, Paul G. Lysko, Jeffrey M. Stadel
Publikováno v:
Journal of Biological Chemistry. 273:4282-4287
Chemokines play an important role in the regulation of endothelial cell (EC) function, including proliferation, migration and differentiation during angiogenesis, and re-endothelialization after injury. In this study, reverse transcriptase-polymerase
Autor:
Xinkang Wang, Kodandaram Pillarisetti, Giora Z. Feuerstein, Tian-Li Yue, Juan-Li Gu, Shalley K. Gupta, Timothy K. Hart, Calvert Louden, Paul G. Lysko
Publikováno v:
Molecular Pharmacology. 51:951-962
2-Methoxyestradiol (2-ME) is an endogenous metabolite of estradiol-17beta and the oral contraceptive agent 17-ethylestradiol. 2-ME was recently reported to inhibit endothelial cell proliferation. The current study was undertaken to explore the mechan
Publikováno v:
IUBMB Life. 40:551-560
CC-chemokine receptors form a closely linked locus in the p21-23 region on the short arm of human chromosome 3. We report the isolation of a novel chemokine receptor like gene from a 'human chromosome 3 specific' genomic library, screened by cross-hy
Publikováno v:
Proceedings of the National Academy of Sciences. 92:7799-7803
Platelet factor 4 (PF-4) is an archetype of the "chemokine" family of low molecular weight proteins that play an important role in injury responses and inflammation. From activated human leukocyte culture supernatants, we have isolated a form of PF-4
Autor:
Shalley K. Gupta, Jai Pal Singh
Publikováno v:
The Journal of Cell Biology
Modulation of endothelial cell proliferation and cell cycle progression by the "chemokine" platelet factor-4 (PF-4) was investigated. PF-4 inhibited DNA synthesis, as well as proliferation of endothelial cells derived from large and small blood vesse