Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Shalini V. Rao"'
Autor:
Yang Wu, Zheqi Li, Abdalla M. Wedn, Allison N. Casey, Daniel Brown, Shalini V. Rao, Soleilmane Omarjee, Jagmohan Hooda, Jason S. Carroll, Jason Gertz, Jennifer M. Atkinson, Adrian V. Lee, Steffi Oesterreich
Publikováno v:
Molecular Cancer Research. 21:591-604
Estrogen receptor alpha (ER/ESR1) mutations occur in 30% to 40% of endocrine resistant ER-positive (ER+) breast cancer. Forkhead box A1 (FOXA1) is a key pioneer factor mediating ER–chromatin interactions and endocrine response in ER+ breast cancer,
Autor:
Steffi Oesterreich, Adrian V. Lee, Jennifer M. Atkinson, Jason Gertz, Jason S. Carroll, Jagmohan Hooda, Soleilmane Omarjee, Shalini V. Rao, Daniel Brown, Allison N. Casey, Abdalla M. Wedn, Zheqi Li, Yang Wu
Estrogen receptor alpha (ER/ESR1) mutations occur in 30% to 40% of endocrine resistant ER-positive (ER+) breast cancer. Forkhead box A1 (FOXA1) is a key pioneer factor mediating ER–chromatin interactions and endocrine response in ER+ breast cancer,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12a2ed57172cf4dc081f4403648a1e2b
https://doi.org/10.1158/1541-7786.c.6573877.v1
https://doi.org/10.1158/1541-7786.c.6573877.v1
Autor:
Steffi Oesterreich, Adrian V. Lee, Jennifer M. Atkinson, Jason Gertz, Jason S. Carroll, Jagmohan Hooda, Soleilmane Omarjee, Shalini V. Rao, Daniel Brown, Allison N. Casey, Abdalla M. Wedn, Zheqi Li, Yang Wu
S1. FOXA1 redistribution in ESR1 mutant cells causes distinct ER-FOXA1 interaction.S2. FOXA1 gained peaks annotated genes are significantly associated with novel target genes.S3. FOXA1 redistribution in ESR1 mutant cells confers potential RXR binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c12d03baf664d3111b46bf66e4ed650
https://doi.org/10.1158/1541-7786.22593319.v1
https://doi.org/10.1158/1541-7786.22593319.v1
Autor:
Steffi Oesterreich, Adrian V. Lee, Jennifer M. Atkinson, Jason Gertz, Jason S. Carroll, Jagmohan Hooda, Soleilmane Omarjee, Shalini V. Rao, Daniel Brown, Allison N. Casey, Abdalla M. Wedn, Zheqi Li, Yang Wu
Table S1. Data Sets UsedTable S2. FOXA1 and ER Chip-seq peaksTable S3. DE genesTable S4. Enriched FOXA1 peak motifsTable S5. Enriched IPA pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7b12dbdcef5cd2915b6960559f5049c
https://doi.org/10.1158/1541-7786.22593316
https://doi.org/10.1158/1541-7786.22593316
Autor:
Catarina Pelicano, Joshua Kent, Valar Franklin, Kamal Kishore, Giulia Biffi, Igor Chernukhin, Shalini V. Rao, Jason S. Carroll
Publikováno v:
Pancreatology. 23:e9
Autor:
Shalini V. Rao, Lisa Young, Danya Cheeseman, Stephanie Mack, Jill Temple, Chandra Shekar Reddy Chilamakuri, Evangelia Papachristou, Amy Smith, Dominique-Laurent Couturier, Romana Ranftl, null Michael Gill, Duncan Jodrell, Alasdair Russell, Igor Chernukhin, Jason Carroll
Publikováno v:
Pancreatology. 23:e10
Autor:
Cara Brodie, Danya Cheeseman, Dominique-Laurent Couturier, Sanjeev Kumar, Jason S. Carroll, Naomi Guppy, Kosuke Yusa, Evangelia K. Papachristou, Sankari Nagarajan, Jose-Enrique Gonzalez Prada, Carlos Caldas, Alejandra Bruna, Joseph Sutton, Shanade Dunn, Emily Archer Goode, Silvia-Elena Glont, Rachael Natrajan, Shalini V. Rao, Igor Chernukhin, Rasmus Siersbæk, Kamal Kishore, Chandra Sekhar Reddy Chilamakuri, Alasdair Russell
Publikováno v:
Nature Genetics
Nature genetics
Nagarajan, S, Rao, S V, Sutton, J, Cheeseman, D, Dunn, S, Papachristou, E K, Prada, J G, Couturier, D, Kumar, S, Kishore, K, Chilamakuri, C S R, Glont, S, Archer Goode, E, Brodie, C, Guppy, N, Natrajan, R, Bruna, A, Caldas, C, Russell, A, Siersbæk, R, Yusa, K, Chernukhin, I & Carroll, J S 2020, ' ARID1A influences HDAC1/BRD4 activity, intrinsic proliferative capacity and breast cancer treatment response ', Nature Genetics, vol. 52, no. 2, pp. 187-197 . https://doi.org/10.1038/s41588-019-0541-5
Nature genetics
Nagarajan, S, Rao, S V, Sutton, J, Cheeseman, D, Dunn, S, Papachristou, E K, Prada, J G, Couturier, D, Kumar, S, Kishore, K, Chilamakuri, C S R, Glont, S, Archer Goode, E, Brodie, C, Guppy, N, Natrajan, R, Bruna, A, Caldas, C, Russell, A, Siersbæk, R, Yusa, K, Chernukhin, I & Carroll, J S 2020, ' ARID1A influences HDAC1/BRD4 activity, intrinsic proliferative capacity and breast cancer treatment response ', Nature Genetics, vol. 52, no. 2, pp. 187-197 . https://doi.org/10.1038/s41588-019-0541-5
Using genome-wide clustered regularly interspaced short palindromic repeats (CRISPR) screens to understand endocrine drug resistance, we discovered ARID1A and other SWI/SNF complex components as the factors most critically required for response to tw
Autor:
Catherine Taylor Nordgård, Shalini V. Rao, Frances M. Richards, Sabina P. Strand, Duncan I. Jodrell, Aarthi Gopinathan, Tonje S. Steigedal, Kurt Ingar Draget
Publikováno v:
Pancreatology. 20:e8
Autor:
Dominique-Laurent Couturier, Jose-Enrique Gonzalez Prada, Rachael Natrajan, Carlos Caldas, Rasmus Siersbæk, Kamal Kishore, Shalini V. Rao, Igor Chernukhin, Cara Brodie, Jason S. Carroll, Silvia-Elena Glont, Alejandra Bruna, Chandra Sekhar Reddy Chilamakuri, Emily Archer Goode, Evangelia K. Papachristou, Alasdair Russell, Sankari Nagarajan, Danya Cheeseman, Naomi Guppy, Sanjeev Kumar, Kosuke Yusa, Joseph Sutton, Shanade Dunn
Publikováno v:
Nature Genetics. 52:354-354
Autor:
Sabina S. Strand, Shalini V. Rao, Aarthi Gopinathan, Catherine Taylor Nordgård, Synnøve Magnussen, Duncan I. Jodrell, Kurt Ingar Draget, Tonje S. Steigedal, Frances M. Richards
Publikováno v:
Cancer Research. 78:627-627
The use of oligosaccharides as active pharmaceutical ingredients lags behind that of other biological molecules such as proteins and nucleic acids. However, there is now a growing understanding of the complex biological functions of saccharide struct