Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Shalini Patiar"'
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35949 (2012)
Low extracellular pH (pH(e)), that is characteristic of many tumours, tends to reduce the uptake of weakly basic drugs, such as doxorubicin, thereby conferring a degree of physiological resistance to chemotherapy. It has been assumed, from pH-partiti
Externí odkaz:
https://doaj.org/article/dc37268d584641acb77f65c9b256d2b6
Autor:
Adrian L. Harris, Pawel Swietach, Richard D. Vaughan-Jones, William S. Sly, Kevin Gatter, Cameron Snell, Russell Leek, Helen Turley, Ioanna Ledaki, Ji-liang Li, Simon Wigfield, Shalini Patiar, Alan McIntyre
(72 KB)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fdc789bf64d005a58a39783951b9ca3
https://doi.org/10.1158/1078-0432.22443911
https://doi.org/10.1158/1078-0432.22443911
Autor:
Adrian L. Harris, Pawel Swietach, Richard D. Vaughan-Jones, William S. Sly, Kevin Gatter, Cameron Snell, Russell Leek, Helen Turley, Ioanna Ledaki, Ji-liang Li, Simon Wigfield, Shalini Patiar, Alan McIntyre
Purpose: Bevacizumab, an anti-VEGFA antibody, inhibits the developing vasculature of tumors, but resistance is common. Antiangiogenic therapy induces hypoxia and we observed increased expression of hypoxia-regulated genes, including carbonic anhydras
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f44ccc35304b124147cf4893c476a8a3
https://doi.org/10.1158/1078-0432.c.6520010.v1
https://doi.org/10.1158/1078-0432.c.6520010.v1
Autor:
Adrian L. Harris, Pawel Swietach, Richard D. Vaughan-Jones, William S. Sly, Kevin Gatter, Cameron Snell, Russell Leek, Helen Turley, Ioanna Ledaki, Ji-liang Li, Simon Wigfield, Shalini Patiar, Alan McIntyre
(1543 KB) - Analysis of the viable tumour volume at the first endpoint of the HCT116 and HT29 xenograft and spheroid experiments revealed that the CAIX expressors had increased viable tissue in HCT116 (A) xenografts (40% more viable tissue at day 14,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::046b047b2dfb1cebd9a0eb2a4a3ce9fa
https://doi.org/10.1158/1078-0432.22443923.v1
https://doi.org/10.1158/1078-0432.22443923.v1
Autor:
Adrian L. Harris, Pawel Swietach, Richard D. Vaughan-Jones, William S. Sly, Kevin Gatter, Cameron Snell, Russell Leek, Helen Turley, Ioanna Ledaki, Ji-liang Li, Simon Wigfield, Shalini Patiar, Alan McIntyre
(244 KB) - Bar chart of scoring of immunohistochemistry and representative immunohistochemistry images of HT29 shCA9 and EV xenografts with and without Bevacizumab treatment. CAIX expression (**p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::234dcc6a320157bc675025f7a876c7de
https://doi.org/10.1158/1078-0432.22443917
https://doi.org/10.1158/1078-0432.22443917
Autor:
Adrian L. Harris, Pawel Swietach, Richard D. Vaughan-Jones, William S. Sly, Kevin Gatter, Cameron Snell, Russell Leek, Helen Turley, Ioanna Ledaki, Ji-liang Li, Simon Wigfield, Shalini Patiar, Alan McIntyre
(8129 KB) - Bar chart of scoring of immunohistochemistry and representative immunohistochemistry images of HT29 xenografts with and without acetazolomide and/or Bevacizumab treatment. CAIX expression (vehicle (DMSO) *p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12b78679de9bfe3d82a5e2e8daaa850b
https://doi.org/10.1158/1078-0432.22443914.v1
https://doi.org/10.1158/1078-0432.22443914.v1
Autor:
Adrian L. Harris, Pawel Swietach, Richard D. Vaughan-Jones, William S. Sly, Kevin Gatter, Cameron Snell, Russell Leek, Helen Turley, Ioanna Ledaki, Ji-liang Li, Simon Wigfield, Shalini Patiar, Alan McIntyre
(1056 KB) - Analysis of CA9 RNA expression in U87 xenografts untreated and with chronic Bevacizumab treatment. Bevacizumab treatement increased CA9 expression (***p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c7449a2b7910b2df8a92e5174d66b2f
https://doi.org/10.1158/1078-0432.22443920.v1
https://doi.org/10.1158/1078-0432.22443920.v1
Autor:
Helen R Valentine, Guy N J Betts, Amanda Eustace, Carla S. Möller-Levet, Crispin J. Miller, Shalini Patiar, Francesca M. Buffa, Jarrod J Homer, Catharine M L West, Gillian Hall, Anassuya Ramachandran, Joely J Irlam, Ashirwad Merve, Adrian L. Harris
Background and purpose: Tumour hypoxia is associated with a poor prognosis in head and neck squamous cell carcinoma (HNSCC), however there is no accepted method for assessing hypoxia clinically. We aimed to conduct a technical validation of a hypoxia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62860c443968aac6685d59eebb387d92
https://doi.org/10.1016/j.ejca.2012.07.028
https://doi.org/10.1016/j.ejca.2012.07.028
Publikováno v:
The Cochrane database of systematic reviews. 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2c2142ae321f438c58f67c06e8a6abdf
https://pubmed.ncbi.nlm.nih.gov/21735400
https://pubmed.ncbi.nlm.nih.gov/21735400
Autor:
Pablo Martinez-Devesa, Shalini Patiar
Publikováno v:
Cochrane Database of Systematic Reviews.
This is an update of a Cochrane Review first published in The Cochrane Library in Issue 1, 2007.Benign nasal polyps are lesions that arise from the mucosa of the nasal cavity or one or more of the nasal sinuses. The presenting symptoms are nasal obst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aafa0f80b8a370ba10cb4d93a557624
https://doi.org/10.1002/14651858.cd005232.pub4
https://doi.org/10.1002/14651858.cd005232.pub4