Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Shalina S. Ousman"'
Autor:
Erin-Mai F. Lim, Vahid Hoghooghi, Kathleen M. Hagen, Kunal Kapoor, Ariana Frederick, Trisha M. Finlay, Shalina S. Ousman
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-16 (2021)
Abstract Background Inflammation constitutes both positive and negative aspects to recovery following peripheral nerve injury. Following damage to the peripheral nervous system (PNS), immune cells such as macrophages play a beneficial role in creatin
Externí odkaz:
https://doaj.org/article/1b758707d018422d8ec2e48a05da97c2
Autor:
Kathleen M. Hagen, Shalina S. Ousman
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-18 (2021)
Abstract Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) consists of various autoimmune subtypes in which the peripheral nervous system (PNS) is attacked. CIDP can follow a relapsing-remitting or progressive course where the resultan
Externí odkaz:
https://doaj.org/article/977ce8e3dbee407caf0dfc96ce4b1350
Autor:
Daniel Umansky, Kathleen M. Hagen, Tak Ho Chu, Rajesh K. Pathiyil, Saud Alzahrani, Shalina S. Ousman, Rajiv Midha
Publikováno v:
Biomolecules, Vol 12, Iss 10, p 1355 (2022)
Objective: To develop a standardized model of stretch–crush sciatic nerve injury in mice, and to compare outcomes of crush and novel stretch–crush injuries using standard manual gait and sensory assays, and compare them to both semi-automated as
Externí odkaz:
https://doaj.org/article/779ce48c74b7477aba0fb6b9f32809e8
Autor:
Kathleen M. Hagen, Shalina S. Ousman
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2021)
Guillain-Barré syndrome (GBS) is a paralyzing autoimmune condition affecting the peripheral nervous system (PNS). Within GBS there are several variants affecting different aspects of the peripheral nerve. In general, there appears to be a role for T
Externí odkaz:
https://doaj.org/article/46cf1a7685044163876ab1ad019c4338
Autor:
Vahid Hoghooghi, Alexandra L. Palmer, Ariana Frederick, Yulan Jiang, Jessica E. Merkens, Anjali Balakrishnan, Trisha M. Finlay, Anders Grubb, Efrat Levy, Paul Gordon, Frank R. Jirik, Minh Dang Nguyen, Carol Schuurmans, Frank Visser, Shannon E. Dunn, Shalina S. Ousman
Publikováno v:
Cell Reports, Vol 33, Iss 1, Pp 108236- (2020)
Summary: The cysteine protease inhibitor Cystatin C (CST3) is highly expressed in the brains of multiple sclerosis (MS) patients and C57BL/6J mice with experimental autoimmune encephalomyelitis (EAE; a model of MS), but its roles in the diseases are
Externí odkaz:
https://doaj.org/article/a4620914131449128eaa04ff10db8078
Autor:
Alexandra L. Palmer, Shalina S. Ousman
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
By 2050, the aging population is predicted to expand by over 100%. Considering this rapid growth, and the additional strain it will place on healthcare resources because of age-related impairments, it is vital that researchers gain a deeper understan
Externí odkaz:
https://doaj.org/article/b1ed65114962441281fa4b44e27b3dfa
Autor:
Shalina S. Ousman, Kathleen M. Hagen
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-18 (2021)
Journal of Neuroinflammation
Journal of Neuroinflammation
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) consists of various autoimmune subtypes in which the peripheral nervous system (PNS) is attacked. CIDP can follow a relapsing-remitting or progressive course where the resultant demyeli
Autor:
Trisha M. Finlay, Vahid Hoghooghi, Ariana Frederick, Kathleen M. Hagen, Shalina S. Ousman, Kunal Kapoor, Erin-Mai F. Lim
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-16 (2021)
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-16 (2021)
BackgroundInflammation constitutes both positive and negative aspects to recovery following peripheral nerve injury. Following damage to the peripheral nervous system (PNS), immune cells such as macrophages play a beneficial role in creating a suppor
Autor:
Shalina S. Ousman, Kathleen M. Hagen
Publikováno v:
Frontiers in Aging Neuroscience
Frontiers in Aging Neuroscience, Vol 12 (2021)
Frontiers in Aging Neuroscience, Vol 12 (2021)
Guillain-Barré syndrome (GBS) is a paralyzing autoimmune condition affecting the peripheral nervous system (PNS). Within GBS there are several variants affecting different aspects of the peripheral nerve. In general, there appears to be a role for T
Autor:
Shigeki Tsutsui, Andrew V. Caprariello, Vahid Hoghooghi, Megan L. Morgan, Jason R. Plemel, Adam Koebel, James A. Rogers, Peter K. Stys, Jeff F. Dunn, Shalina S. Ousman, Lakshmi P. Kotra, V. Wee Yong
Publikováno v:
Proceedings of the National Academy of Sciences. 115:5528-5533
Although immune attack against central nervous system (CNS) myelin is a central feature of multiple sclerosis (MS), its root cause is unresolved. In this report, we provide direct evidence that subtle biochemical modifications to brain myelin elicit