Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Shalin Kothari"'
Autor:
Narendranath Epperla, Qiuhong Zhao, Sayan Mullick Chowdhury, Lauren Shea, Tamara K. Moyo, Nishitha Reddy, Julia Sheets, David M. Weiner, Praveen Ramakrishnan Geethakumari, Malathi Kandarpa, Ximena Jordan Bruno, Colin Thomas, Michael C. Churnetski, Andrew Hsu, Luke Zurbriggen, Cherie Tan, Kathryn Lindsey, Joseph Maakaron, Paolo F. Caimi, Pallawi Torka, Celeste Bello, Sabarish Ayyappan, Reem Karmali, Seo-Hyun Kim, Anna Kress, Shalin Kothari, Yazeed Sawalha, Beth Christian, Kevin A. David, Irl Brian Greenwell, Murali Janakiram, Vaishalee P. Kenkre, Adam J. Olszewski, Jonathon B. Cohen, Neil Palmisiano, Elvira Umyarova, Ryan A. Wilcox, Farrukh T. Awan, Juan Pablo Alderuccio, Stefan K. Barta, Natalie S. Grover, Nilanjan Ghosh, Nancy L. Bartlett, Alex F. Herrera, Geoffrey Shouse
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-6 (2022)
Abstract Ibrutinib is effective in the treatment of relapsed/refractory (R/R) marginal zone lymphoma (MZL) with an overall response rate (ORR) of 48%. However, factors associated with response (or lack thereof) to ibrutinib in R/R MZL in clinical pra
Externí odkaz:
https://doaj.org/article/742e9377f2884da1b8eeb0b6ff560e57
Autor:
Harsh Shah, Victoria Vardell, Erin Zacholski, Amanda Fegley, Kalub Fedak, Suchitra Sundaram, Sridevi Rajeeve, Gaurav Goyal, Haris Hatic, Pallawi Torka, Sheeba Ba Aqeel, Azra Borogovac, Kira Macdougall, Shalin Kothari, Anna Kress, Dipenkumar Modi, Elizabeth Travers, Nitin Chilakamarri, Elizabeth Brem, Deborah M. Stephens, Boyu Hu, Lindsey Fitzgerlad, Charlotte Wagner, Daniel Ermann
Publikováno v:
HemaSphere, Vol 6, Pp 47-48 (2022)
Externí odkaz:
https://doaj.org/article/12d2af81c3be476aa4cbc5e716cec24c
Autor:
Pallawi Torka, Cory Mavis, Shalin Kothari, Sarah Belliotti, Juan Gu, Suchitra Sundaram, Matthew Barth, Francisco J. Hernandez‐Ilizaliturri
Publikováno v:
eJHaem, Vol 1, Iss 1, Pp 122-132 (2020)
Abstract We studied the biological activity of pevonedistat, a first‐in‐class NEDD8‐activating enzyme (NAE) inhibitor, in combination with various cytotoxic chemotherapy agents and small molecule inhibitors in lymphoma preclinical models. Pevon
Externí odkaz:
https://doaj.org/article/548b20b649834364a3510b398fbb98fc
Autor:
Philippa Li, Giulia Biancon, Timil Patel, Zenggang Pan, Shalin Kothari, Stephanie Halene, Thomas Prebet, Mina L. Xu
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Mast cell leukemia with associated hematologic neoplasm (MCL-AHN) is a rare and highly aggressive entity that remains understudied due to the paucity of cases. We present a case of a 45-year-old man who was concurrently diagnosed with mast cell leuke
Externí odkaz:
https://doaj.org/article/909927bb416e484c9dd5fb59a52c83bc
Autor:
Ahmad Shariftabrizi, Shalin Kothari, Saby George, Kristopher Attwood, Ellis Levine, Dominick Lamonica
Publikováno v:
The Oncologist. 28:246-251
Background Radium-223 dichloride (Ra-223) is now frequently used to treat prostate cancer that has metastasized to bone, although patient selection continues to be suboptimal for determining who will benefit most from this novel treatment modality. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60849157edbf9363d8b186a4dc90af9b
https://doi.org/10.1093/oncolo/oyac245
https://doi.org/10.1093/oncolo/oyac245
Publikováno v:
Blood Cancer Discovery. 4:8-11
Summary:The use of genomic data to analyze primary endpoints for clinical trials in diffuse large B-cell lymphomas (DLBCL) significantly improved the development of rational drug combinations for genetically defined patient subsets. Recent genetic mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ba9c67d7f665611c0aea6d817ec15b2
https://doi.org/10.1158/2643-3230.bcd-22-0180
https://doi.org/10.1158/2643-3230.bcd-22-0180
Autor:
Kadriye Nehir Cosgun, Huda Jumaa, Mark E. Robinson, Klaus M. Kistner, Liang Xu, Gang Xiao, Lai N. Chan, Jaewoong Lee, Kohei Kume, Etienne Leveille, David Fonseca-Arce, Dhruv Khanduja, Han Leng Ng, Niklas Feldhahn, Joo Song, Wing-Chung Chan, Jianjun Chen, M. Mark Taketo, Shalin Kothari, Matthew S. Davids, Hilde Schjerven, Julia Jellusova, Markus Müschen
Publikováno v:
bioRxiv
In most cell types, nuclear β-catenin functions as prominent oncogenic driver and pairs with TCF7-family factors for transcriptionalactivationof MYC. Surprisingly, B-lymphoid malignancies not only lacked expression and activating lesions of β-caten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de1f21543f9597e44be327c451d0a6a9
https://europepmc.org/articles/PMC10054980/
https://europepmc.org/articles/PMC10054980/
Autor:
Dongjoo Kim, Giulia Biancon, Zhiliang Bai, Jennifer VanOudenhove, Yuxin Liu, Shalin Kothari, Lohith Gowda, Jennifer M. Kwan, Nicholas Carlos Buitrago-Pocasangre, Nikhil Lele, Hiromitsu Asashima, Michael K. Racke, JoDell E. Wilson, Tara S. Givens, Mary M. Tomayko, Wade L. Schulz, Erin E. Longbrake, David A. Hafler, Stephanie Halene, Rong Fan
Publikováno v:
bioRxiv : the preprint server for biology.
The immune response to SARS-CoV-2 for patients with altered immunity such as hematologic malignancies and autoimmune disease may differ substantially from that in general population. These patients remain at high risk despite wide-spread adoption of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::360ceae1ece027bcde513e7eb012b443
https://pubmed.ncbi.nlm.nih.gov/36093346
https://pubmed.ncbi.nlm.nih.gov/36093346
Autor:
Amy J. Davidoff, Cary P. Gross, Scott F. Huntington, Shalin Kothari, Iris Isufi, Kishan Patel
Publikováno v:
Blood. 136:1946-1955
The ALLIANCE A041202 trial found that continuously administered ibrutinib in the first-line setting significantly prolonged progression-free survival compared with a fixed-duration treatment of rituximab and bendamustine in older adults with chronic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf868cdc98aca0551843fa3f000cc47d
https://doi.org/10.1182/blood.2020004922
https://doi.org/10.1182/blood.2020004922
Autor:
Sarah Belliotti, Shalin Kothari, Francisco J. Hernandez-Ilizaliturri, Suchitra Sundaram, Matthew J. Barth, Juan Gu, Pallawi Torka, Cory Mavis
Publikováno v:
EJHaem
We studied the biological activity of pevonedistat, a first-in-class NEDD8-activating enzyme (NAE) inhibitor, in combination with various cytotoxic chemotherapy agents and small molecule inhibitors in lymphoma pre-clinical models. Pevonedistat induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f770b2d962a1241a7ce6b69ac7a6a8b
https://doi.org/10.1002/jha2.2
https://doi.org/10.1002/jha2.2