Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Shalev, Itzkovitz"'
Autor:
Stav Dan, Bella Ungar, Shani Ben-Moshe, Keren Bahar Halpern, Miri Yavzori, Ella Fudim, Orit Picard, Chaya Mushka Abitbol, Sivan Harnik, Iris Barshack, Uri Kopylov, Shomron Ben-Horin, Shalev Itzkovitz
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 16, Iss 1, Pp 1-15 (2023)
Background & Aims: Noninvasive modalities for assessing active endoscopic and histologic inflammation in Crohn’s disease and ulcerative colitis patients are critically needed. Fecal wash host shed-cell transcriptomics has been shown to be a robust
Externí odkaz:
https://doaj.org/article/6bf6f05d637e4258a95891889dccaca2
Autor:
Maria Polychronidou, Jingyi Hou, M Madan Babu, Prisca Liberali, Ido Amit, Bart Deplancke, Galit Lahav, Shalev Itzkovitz, Matthias Mann, Julio Saez‐Rodriguez, Fabian Theis, Roland Eils
Publikováno v:
Molecular Systems Biology, Vol 19, Iss 7, Pp n/a-n/a (2023)
Externí odkaz:
https://doaj.org/article/7ddb6c78b1e24454801a548f8ec9f20e
Autor:
Adi Egozi, Oluwabunmi Olaloye, Lael Werner, Tatiana Silva, Blake McCourt, Richard W Pierce, Xiaojing An, Fujing Wang, Kong Chen, Jordan S Pober, Dror Shouval, Shalev Itzkovitz, Liza Konnikova
Publikováno v:
PLoS Biology, Vol 21, Iss 5, p e3002124 (2023)
Necrotizing enterocolitis (NEC) is a gastrointestinal complication of premature infants with high rates of morbidity and mortality. A comprehensive view of the cellular changes and aberrant interactions that underlie NEC is lacking. This study aimed
Externí odkaz:
https://doaj.org/article/9b1581b62447470ea9e8a8526e8a60d5
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Combining scRNA-seq with spatial information to enable the reconstruction of spatially-resolved cell atlases is challenging for rare cell types. Here the authors present ClumpSeq, an approach for sequencing small clumps of tissue attached cells, and
Externí odkaz:
https://doaj.org/article/afa3c10f1b32444b80e1d582eef76aa2
Autor:
Eran Yanowski, Nancy S. Yacovzada, Eyal David, Amir Giladi, Diego Jaitin, Lydia Farack, Adi Egozi, Danny Ben-Zvi, Shalev Itzkovitz, Ido Amit, Eran Hornstein
Publikováno v:
Molecular Metabolism, Vol 60, Iss , Pp 101467- (2022)
Objectives: Until recently, communication between neighboring cells in islets of Langerhans was overlooked by genomic technologies, which require rigorous tissue dissociation into single cells. Methods: We utilize sorting of physically interacting ce
Externí odkaz:
https://doaj.org/article/cdb06bc625b64311ac86dce808148b44
Autor:
Eman Khatib-Massalha, Suditi Bhattacharya, Hassan Massalha, Adi Biram, Karin Golan, Orit Kollet, Anju Kumari, Francesca Avemaria, Ekaterina Petrovich-Kopitman, Shiri Gur-Cohen, Tomer Itkin, Isabell Brandenburger, Asaf Spiegel, Ziv Shulman, Zachary Gerhart-Hines, Shalev Itzkovitz, Matthias Gunzer, Stefan Offermanns, Ronen Alon, Amiram Ariel, Tsvee Lapidot
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Lactate is a by-product of glycolysis that can function via its G protein receptor GPR81. Here the authors show that LPS or Salmonella infection enhances glycolytic metabolism in bone marrow neutrophils, resulting in lactate production, which increas
Externí odkaz:
https://doaj.org/article/fd9905e2c6a74145a36f74cbae797fa7
Autor:
Keren Bahar Halpern, Hassan Massalha, Rachel K. Zwick, Andreas E. Moor, David Castillo-Azofeifa, Milena Rozenberg, Lydia Farack, Adi Egozi, Dan R. Miller, Inna Averbukh, Yotam Harnik, Noa Weinberg-Corem, Frederic J. de Sauvage, Ido Amit, Ophir D. Klein, Michal Shoshkes-Carmel, Shalev Itzkovitz
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Epithelial gene expression has been shown to be zonated along the crypt-villus axis, but mechanisms shaping this spatial variability were unknown. Here, Bahar Halpern et al. uncover zonation of mesenchymal cells, including Lgr5+ telocytes, which regu
Externí odkaz:
https://doaj.org/article/06a4059134d14359ba2c09cd1b2ad006
Autor:
Noam Cohen, Hassan Massalha, Shani Ben-Moshe, Adi Egozi, Milena Rozenberg, Keren Bahar Halpern, Shalev Itzkovitz
Publikováno v:
PLoS Biology, Vol 19, Iss 10, p e3001214 (2021)
The intestine is lined with isolated lymphoid follicles (ILFs) that facilitate sampling of luminal antigens to elicit immune responses. Technical challenges related to the scarcity and small sizes of ILFs and their follicle-associated epithelium (FAE
Externí odkaz:
https://doaj.org/article/b9bbf4c2f6db41be9fc3a64ef0c9b256
Autor:
Shiri Kult, Tsviya Olender, Marco Osterwalder, Svetalana Markman, Dena Leshkowitz, Sharon Krief, Ronnie Blecher-Gonen, Shani Ben-Moshe, Lydia Farack, Hadas Keren-Shaul, Tomer-Meir Salame, Terence D Capellini, Shalev Itzkovitz, Ido Amit, Axel Visel, Elazar Zelzer
Publikováno v:
eLife, Vol 10 (2021)
The mechanical challenge of attaching elastic tendons to stiff bones is solved by the formation of a unique transitional tissue. Here, we show that murine tendon-to-bone attachment cells are bi-fated, activating a mixture of chondrocyte and tenocyte
Externí odkaz:
https://doaj.org/article/d634c0b6552b4485bd6640c59f2a7db5
Autor:
Hassan Massalha, Keren Bahar Halpern, Samir Abu‐Gazala, Tamar Jana, Efi E Massasa, Andreas E Moor, Lisa Buchauer, Milena Rozenberg, Eli Pikarsky, Ido Amit, Gideon Zamir, Shalev Itzkovitz
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 12, Pp n/a-n/a (2020)
Abstract Malignant cell growth is fueled by interactions between tumor cells and the stromal cells composing the tumor microenvironment. The human liver is a major site of tumors and metastases, but molecular identities and intercellular interactions
Externí odkaz:
https://doaj.org/article/c1d13de27e154463b8e3601a5983c967