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of 188
pro vyhledávání: '"Shalek, AK"'
Autor:
Regev, A, Teichmann, SA, Lander, ES, Amit, I, Benoist, C, Birney, E, Bodenmiller, B, Campbell, PJ, Carninci, P, Clatworthy, M, Clevers, H, Deplancke, B, Dunham, I, Eberwine, J, Eils, R, Enard, W, Farmer, A, Fugger, L, Göttgens, B, Hacohen, N, Haniffa, M, Hemberg, M, Kim, SK, Klenerman, P, Kriegstein, A, Lein, E, Linnarsson, S, Lundberg, E, Lundeberg, J, Majumder, P, Marioni, JC, Merad, M, Mhlanga, M, Nawijn, M, Netea, M, Nolan, G, Pe'er, D, Phillipakis, A, Ponting, CP, Quake, SR, Reik, W, Rozenblatt-Rosen, O, Sanes, JR, Satija, R, Schumacher, TN, Shalek, AK, Shapiro, E, Sharma, P, Shin, JW, Stegle, O, Stratton, MR, Stubbington, MJT, Theis, FJ, Uhlen, M, van Oudenaarden, A, Wagner, A, Watt, FM, Weissman, JS, Wold, BJ, Xavier, RJ, Yosef, N
The recent advent of methods for high-throughput single-cell molecular profiling has catalyzed a growing sense in the scientific community that the time is ripe to complete the 150-year-old effort to identify all cell types in the human body. The Hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f30a0e14d984ce1edece507acc572dcd
https://ora.ox.ac.uk/objects/uuid:4f6fd5b8-a1d7-48ba-8391-2877bb870300
https://ora.ox.ac.uk/objects/uuid:4f6fd5b8-a1d7-48ba-8391-2877bb870300
Akademický článek
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Autor:
Nir Yosef, Mark F. Ciaccio, Thomas Eisenhaure, Marciela M. DeGrace, Philipp Mertins, Richard Bradley Jones, Matteo Iannacone, Elena Tonti, Irit Gat-Viks, Hongkun Park, Ido Amit, Steven A. Carr, Jacob T. Robinson, Manuel Garber, Mette S. Andersen, Alex K. Shalek, Nicolas Chevrier, David E. Root, Maxim N. Artyomov, Amy Sutton, Ulrich H. von Andrian, Karl R. Clauser, Nir Hacohen, Aviv Regev
SUMMARY Deciphering the signaling networks that underlie normal and disease processes remains a major challenge. Here, we report the discovery of signaling components involved in the Toll-like receptor (TLR) response of immune dendritic cells (DCs),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d302bb94dd3189676b5aea8f85431be
Autor:
Amit I; Weizmann Institute of Science, Rehovot, Israel., Ardlie K; Broad Institute, Cambridge, USA., Arzuaga F; Ministry of Science, Technology and Productive Innovation, Buenos Aires, Argentina., Awandare G; West African Center for Cell Biology of Infectious Pathogens, University of Ghana, Legon, Ghana., Bader G; University of Toronto, Toronto, Canada., Bernier A; Centre for Genomics and Policy, McGill University, Montreal, Canada., Carninci P; RIKEN Center for Integrative Medical Sciences, Hokkaido, Japan.; Human Technopole, Milan, Italy., Donnelly S; Broad Institute, Cambridge, USA., Eils R; BIH@Charité - Center for Digital Health, Berlin, Ethiopia., Forrest ARR; Harry Perkins Institute of Medical Research, Perth, Australia., Greely HT; Stanford Law School, Stanford University, California, USA., Guigo R; Center for Genomic Regulation, Universitat Pompeu Fabra, Barcelona, Spain., Hacohen N; Center for Cancer Immunotherapy, Mass General Hospital, Charlestown, USA., Haniffa M; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK., Kirby ES; Centre for Genomics and Policy, McGill University, Montreal, Canada., Knoppers BM; Centre for Genomics and Policy, McGill University, Montreal, Canada., Kriegstein A; University of California, San Fransisco, USA., Lein ES; University of Washington, Seattle, USA., Linnarsson S; Karolinska Institute, Solna, Sweden., Majumder PP; John C. Martin Centre for Liver Research & Innovation, Kolkata, India. ppm@isical.ac.in.; Indian Statistical Institute, Kolkata, India. ppm@isical.ac.in., Merad M; Mount Sinai School of Medicine, New York, USA., Meyer K; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK., Mhlanga MM; RIMLS-Science, Nijmegen, The Netherlands., Nolan G; Stanford University School of Medicine, California, USA., Ntusi NAB; University of Cape Town, South Africa, and SAMRC Extramural Unit on Intersection of Noncommunicable Diseases and Infectious Diseases, Cape Town, South Africa., Pe'er D; Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, USA., Prabhakar S; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Raven-Adams M; Global Alliance for Genomics and Health, Wellcome Sanger Institute, Hinxton, UK., Regev A; Human Cell Atlas, South San Francisco, USA., Rozenblatt-Rosen O; Human Cell Atlas, South San Francisco, USA., Saha S; Child Health Research Foundation, Dhaka, Bangladesh., Saltzman A; Broad Institute, Cambridge, USA., Shalek AK; Broad Institute, Cambridge, USA.; Massachusetts Institute of Technology, Boston, USA., Shin JW; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Stunnenberg H; Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands., Teichmann SA; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK., Tickle T; Broad Institute, Cambridge, USA., Villani AC; Massachusetts General Hospital, Boston, USA., Wells C; University of Melbourne, Melbourne, Australia., Wold B; California Institute of Technology, California, USA., Yang H; BGI-Shenzhen, Shenzhen, China., Zhuang X; Harvard University, Cambridge, USA.
Publikováno v:
Nature communications [Nat Commun] 2024 Nov 20; Vol. 15 (1), pp. 10019. Date of Electronic Publication: 2024 Nov 20.
Autor:
Dilly J; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; The Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Hoffman MT; Harvard Medical School, Boston, Massachusetts.; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts., Abbassi L; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; The Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Li Z; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; The Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Paradiso F; Department of Translational Molecular Pathology, Sheikh Ahmed Center for Pancreatic Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, Texas., Parent BD; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; The Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Hennessey CJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; The Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Jordan AC; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; The Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Morgado M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Dasgupta S; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Uribe GA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; The Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Yang A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; The Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Kapner KS; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; The Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Hambitzer FP; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts., Qiang L; Harvard Medical School, Boston, Massachusetts.; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts., Feng H; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Geisberg J; Department of Data Science, Dana-Farber Cancer Institute, Boston, Massachusetts., Wang J; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Evans KE; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; The Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Lyu H; Therapeutics Discovery Division, TRACTION Platform, The University of Texas MD Anderson Cancer Center, Houston, Texas., Schalck A; Therapeutics Discovery Division, TRACTION Platform, The University of Texas MD Anderson Cancer Center, Houston, Texas., Feng N; Therapeutics Discovery Division, TRACTION Platform, The University of Texas MD Anderson Cancer Center, Houston, Texas., Lopez AM; Therapeutics Discovery Division, TRACTION Platform, The University of Texas MD Anderson Cancer Center, Houston, Texas., Bristow CA; Therapeutics Discovery Division, TRACTION Platform, The University of Texas MD Anderson Cancer Center, Houston, Texas., Kim MP; Therapeutics Discovery Division, TRACTION Platform, The University of Texas MD Anderson Cancer Center, Houston, Texas., Rajapakshe KI; Department of Translational Molecular Pathology, Sheikh Ahmed Center for Pancreatic Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, Texas., Bahrambeigi V; Department of Translational Molecular Pathology, Sheikh Ahmed Center for Pancreatic Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, Texas., Roth JA; The Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Garg K; Exact Sciences, Redwood City, California., Guerrero PA; Department of Translational Molecular Pathology, Sheikh Ahmed Center for Pancreatic Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, Texas., Stanger BZ; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Cristea S; The Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Department of Data Science, Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard School of Public Health, Boston, Massachusetts., Lowe SW; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York., Baslan T; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Van Allen EM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Mancias JD; Harvard Medical School, Boston, Massachusetts.; Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Chan E; Amgen Inc., Thousand Oaks, California., Anderson A; Amgen Inc., Thousand Oaks, California., Katlinskaya YV; Amgen Inc., Thousand Oaks, California., Shalek AK; The Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts.; Institute for Medical Engineering and Science, Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts., Hong DS; University of Texas M.D. Anderson Cancer Center, Houston, Texas., Pant S; University of Texas M.D. Anderson Cancer Center, Houston, Texas., Hallin J; Mirati Therapeutics Inc., San Diego, California., Anderes K; Mirati Therapeutics Inc., San Diego, California., Olson P; Mirati Therapeutics Inc., San Diego, California., Heffernan TP; Therapeutics Discovery Division, TRACTION Platform, The University of Texas MD Anderson Cancer Center, Houston, Texas., Chugh S; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; The Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Christensen JG; Mirati Therapeutics Inc., San Diego, California., Maitra A; Department of Translational Molecular Pathology, Sheikh Ahmed Center for Pancreatic Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, Texas., Wolpin BM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts., Raghavan S; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; The Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts., Nowak JA; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts., Winter PS; The Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Dougan SK; Harvard Medical School, Boston, Massachusetts.; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts., Aguirre AJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; The Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.
Publikováno v:
Cancer discovery [Cancer Discov] 2024 Nov 01; Vol. 14 (11), pp. 2135-2161.
Autor:
Zaniker EJ; Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Zhang J; Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, NJ, USA., Russo D; Institute for Medical Engineering & Science, Department of Chemistry, and Koch Institute for Integrative Cancer Research Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Broad Institute, Harvard University & Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; The Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, 02139, USA., Huang R; Thayer School of Engineering, Dartmouth College, Hanover, NH, USA., Suritis K; Thayer School of Engineering, Dartmouth College, Hanover, NH, USA., Drake RS; Institute for Medical Engineering & Science, Department of Chemistry, and Koch Institute for Integrative Cancer Research Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Broad Institute, Harvard University & Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; The Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, 02139, USA., Barlow-Smith E; Micrographia Bio, London, UK., Shalek AK; Institute for Medical Engineering & Science, Department of Chemistry, and Koch Institute for Integrative Cancer Research Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Broad Institute, Harvard University & Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; The Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, 02139, USA., Woodruff TK; Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.; Department of Obstetrics and Gynecology, Michigan State University, East Lansing, MI, USA., Xiao S; Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, NJ, USA., Goods BA; Thayer School of Engineering, Dartmouth College, Hanover, NH, USA. britt.anne.goods@dartmouth.edu., Duncan FE; Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA. f-duncan@northwestern.edu.
Publikováno v:
Communications biology [Commun Biol] 2024 Oct 23; Vol. 7 (1), pp. 1374. Date of Electronic Publication: 2024 Oct 23.
Autor:
Bromley JD; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA; Institute for Medical Engineering and Science (IMES), Massachusetts Institute of Technology, Cambridge, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Graduate Program in Microbiology, Massachusetts Institute of Technology, Cambridge, MA, USA., Ganchua SKC; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Center for Vaccine Research, University of Pittsburgh, Pittsburgh, PA, USA., Nyquist SK; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA; Institute for Medical Engineering and Science (IMES), Massachusetts Institute of Technology, Cambridge, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA, USA., Maiello P; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Chao M; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Borish HJ; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Center for Vaccine Research, University of Pittsburgh, Pittsburgh, PA, USA., Rodgers M; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Center for Vaccine Research, University of Pittsburgh, Pittsburgh, PA, USA., Tomko J; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Center for Vaccine Research, University of Pittsburgh, Pittsburgh, PA, USA., Kracinovsky K; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Center for Vaccine Research, University of Pittsburgh, Pittsburgh, PA, USA., Mugahid D; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Nguyen S; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA; Institute for Medical Engineering and Science (IMES), Massachusetts Institute of Technology, Cambridge, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Wang QD; Institute for Medical Engineering and Science (IMES), Massachusetts Institute of Technology, Cambridge, MA, USA., Rosenberg JM; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Klein EC; Division of Laboratory Animal Research, University of Pittsburgh, Pittsburgh, PA, USA., Gideon HP; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Center for Vaccine Research, University of Pittsburgh, Pittsburgh, PA, USA., Floyd-O'Sullivan R; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA; Institute for Medical Engineering and Science (IMES), Massachusetts Institute of Technology, Cambridge, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Berger B; Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA, USA., Scanga CA; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Center for Vaccine Research, University of Pittsburgh, Pittsburgh, PA, USA., Lin PL; Center for Vaccine Research, University of Pittsburgh, Pittsburgh, PA, USA; Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Fortune SM; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA. Electronic address: sfortune@hsph.harvard.edu., Shalek AK; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA; Institute for Medical Engineering and Science (IMES), Massachusetts Institute of Technology, Cambridge, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA. Electronic address: shalek@mit.edu., Flynn JL; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Center for Vaccine Research, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: joanne@pitt.edu.
Publikováno v:
Immunity [Immunity] 2024 Oct 08; Vol. 57 (10), pp. 2380-2398.e6. Date of Electronic Publication: 2024 Aug 29.
Autor:
Liu N; Institute for Medical Engineering and Science (IMES) and Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.; Program in Computational and Systems Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Kattan WE; Institute for Medical Engineering and Science (IMES) and Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Mead BE; Institute for Medical Engineering and Science (IMES) and Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Kummerlowe C; Institute for Medical Engineering and Science (IMES) and Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.; Program in Computational and Systems Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Cheng T; Institute for Medical Engineering and Science (IMES) and Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Ingabire S; Institute for Medical Engineering and Science (IMES) and Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Cheah JH; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Center for the Development of Therapeutics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Soule CK; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Center for the Development of Therapeutics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Vrcic A; Center for the Development of Therapeutics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., McIninch JK; Center for the Development of Therapeutics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Triana S; Institute for Medical Engineering and Science (IMES) and Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Guzman M; Institute for Medical Engineering and Science (IMES) and Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Dao TT; Institute for Medical Engineering and Science (IMES) and Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Peters JM; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Lowder KE; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Dana Farber Cancer Institute, Boston, MA, USA., Crawford L; Microsoft Research, Cambridge, MA, USA.; Center for Computational Biology, Brown University, Providence, RI, USA.; Department of Biostatistics, Brown University, Providence, RI, USA., Amini AP; Microsoft Research, Cambridge, MA, USA., Blainey PC; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Hahn WC; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Dana Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Cleary B; Faculty of Computing and Data Sciences, Boston University, Boston, MA, USA.; Department of Biomedical Engineering, Boston University, Boston, MA, USA.; Department of Biology, Boston University, Boston, MA, USA., Bryson B; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Winter PS; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Raghavan S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Dana Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Shalek AK; Institute for Medical Engineering and Science (IMES) and Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA. shalek@mit.edu.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA. shalek@mit.edu.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. shalek@mit.edu.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA. shalek@mit.edu.; Program in Computational and Systems Biology, Massachusetts Institute of Technology, Cambridge, MA, USA. shalek@mit.edu.; Program in Immunology, Harvard Medical School, Boston, MA, USA. shalek@mit.edu.; Harvard Stem Cell Institute, Cambridge, MA, USA. shalek@mit.edu.
Publikováno v:
Nature biotechnology [Nat Biotechnol] 2024 Oct 07. Date of Electronic Publication: 2024 Oct 07.
Autor:
Lensch V; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States., Gabba A; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States., Hincapie R; School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332, United States., Bhagchandani SH; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States., Basak A; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts 02139, United States.; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, United States., Alam MM; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States., Noble J; School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332, United States., Irvine DJ; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts 02139, United States.; Howard Hughes Medical Institute, Chevy Chase, Maryland 20815, United States., Shalek AK; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts 02139, United States.; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, United States., Johnson JA; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, United States., Finn MG; School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.; School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia 30332, United States., Kiessling LL; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts 02139, United States.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, United States.
Publikováno v:
ACS nano [ACS Nano] 2024 Oct 01; Vol. 18 (39), pp. 26770-26783. Date of Electronic Publication: 2024 Sep 16.
Autor:
Liang SQ; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, Massachusetts, USA., Navia AW; Institute for Medical Engineering and Science, Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, USA., Ramseier M; Institute for Medical Engineering and Science, Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, USA., Zhou X; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, Massachusetts, USA., Martinez M; Departments of Pediatrics and Cell Biology and Human Anatomy, School of Medicine, and California National Primate Research Center, University of California, Davis, California, USA., Lee C; Departments of Pediatrics and Cell Biology and Human Anatomy, School of Medicine, and California National Primate Research Center, University of California, Davis, California, USA., Zhou C; Horae Gene Therapy Center and Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, USA.; Li Weibo Institute for Rare Diseases Research, University of Massachusetts Medical School, Worcester, Massachusetts, USA., Wu J; Department of Pediatrics, University of Massachusetts Medical School, Worcester, Massachusetts, USA., Xie J; Horae Gene Therapy Center and Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, USA.; Li Weibo Institute for Rare Diseases Research, University of Massachusetts Medical School, Worcester, Massachusetts, USA.; Viral Vector Core, University of Massachusetts Medical School, Worcester, Massachusetts, USA., Su Q; Horae Gene Therapy Center and Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, USA.; Li Weibo Institute for Rare Diseases Research, University of Massachusetts Medical School, Worcester, Massachusetts, USA.; Viral Vector Core, University of Massachusetts Medical School, Worcester, Massachusetts, USA., Wang D; Horae Gene Therapy Center and Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, USA.; Li Weibo Institute for Rare Diseases Research, University of Massachusetts Medical School, Worcester, Massachusetts, USA., Flotte TR; Horae Gene Therapy Center and Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, USA., Anderson DG; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.; Harvard and MIT Division of Health Science and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA., Tarantal AF; Departments of Pediatrics and Cell Biology and Human Anatomy, School of Medicine, and California National Primate Research Center, University of California, Davis, California, USA., Shalek AK; Institute for Medical Engineering and Science, Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, USA., Gao G; Horae Gene Therapy Center and Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, USA.; Li Weibo Institute for Rare Diseases Research, University of Massachusetts Medical School, Worcester, Massachusetts, USA.; Viral Vector Core, University of Massachusetts Medical School, Worcester, Massachusetts, USA., Xue W; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, Massachusetts, USA.; Li Weibo Institute for Rare Diseases Research, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Publikováno v:
Human gene therapy [Hum Gene Ther] 2024 Oct; Vol. 35 (19-20), pp. 814-824. Date of Electronic Publication: 2024 Jul 03.