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pro vyhledávání: '"Shalaka Metkar"'
Publikováno v:
Journal of Leukocyte Biology. 92:389-396
Harnessing the CD14-independent pathway for chemokine induction in severe infection leads to early neutrophil recruitment to the site of infection, enhanced bacterial clearance, and survival. Previous studies have shown that CD14−/− mice are resi
Autor:
Sanna M. Goyert, Jack Silver, Erick Denamur, Alain Haziot, Shanjana Awasthi, Kwang Sik Kim, Sophie C. Gangloff, Shalaka Metkar, Saul Teichberg
Publikováno v:
Infection and Immunity. 75:5415-5424
Severe bacterial infections leading to sepsis or septic shock can be induced by bacteria that utilize different factors to drive pathogenicity and/or virulence, leading to disease in the host. One major factor expressed by all clinical isolates of gr
Autor:
Shalaka Metkar, Ravinder Kodela, Zong Yuan Gan, Mitali Chattopadhyay, Khosrow Kashfi, Niharika Nath, Tomasz Sobocki
Hydrogen sulfide-releasing aspirin (HS-ASA) is a novel compound with potential against cancer. It inhibited the growth of Jurkat T-leukemia cells with an IC₅₀ of 1.9 ± 0.2 μM whereas that of ASA was >5000 μM. It dose-dependently inhibited prol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83eacf339f6aff4a703a231cbfc3d71a
https://europepmc.org/articles/PMC3769470/
https://europepmc.org/articles/PMC3769470/
Autor:
Shalaka Metkar, Mitali Chattopadhyay, Svetlana Kvint, Khosrow Kashfi, Kamran V. Nia, Ravinder Kodela
Publikováno v:
Gastroenterology. 146:S-68
Publikováno v:
The Journal of Immunology. 184:94.16-94.16
Sepsis, characterized by a systemic bacterial infection, is a life-threatening condition that can lead to multi-organ failure and death from septic shock. We have observed that CD14- and TLR4-deficient mice are resistant to death by sepsis from sever