Uncovering the Cardioprotective Potential of Diacerein in Doxorubicin Cardiotoxicity: Mitigating Ferritinophagy-Mediated Ferroptosis via Upregulating NRF2/SLC7A11/GPX4 Axis.

Autor: El-Gohary RM; Medical Biochemistry Department, Faculty of Medicine, Tanta University, Tanta 31511, Egypt., Okasha AH; Medical Biochemistry Department, Faculty of Medicine, Tanta University, Tanta 31511, Egypt., Abd El-Azeem AH; Medical Pharmacology Department, Faculty of Medicine, Tanta University, Tanta 31511, Egypt., Abdel Ghafar MT; Clinical Pathology Department, Faculty of Medicine, Tanta University, Tanta 31511, Egypt., Ibrahim S; Human Anatomy and Embryology Department, Faculty of Medicine, Tanta University, Tanta 31511, Egypt., Hegab II; Medical Physiology Department, Faculty of Medicine, Tanta University, Tanta 31511, Egypt.; Department of Bio-Physiology, Ibn Sina National College for Medical Studies, Jeddah 22413, Saudi Arabia., Farghal EE; Clinical Pathology Department, Faculty of Medicine, Tanta University, Tanta 31511, Egypt., Shalaby SAF; Internal Medicine Department, Faculty of Medicine, Tanta University, Tanta 31511, Egypt., Elshora OA; Clinical Pathology Department, Faculty of Medicine, Tanta University, Tanta 31511, Egypt., ElMehy AE; Forensic Medicine & Clinical Toxicology Department, Faculty of Medicine, Tanta University, Tanta 31511, Egypt., Barakat AN; Pediatric Department, Faculty of Medicine, Tanta University, Tanta 31511, Egypt., Amer BS; Pathology Department, Faculty of Medicine, Tanta University, Tanta 31511, Egypt., Sobeeh FG; Forensic Medicine & Clinical Toxicology Department, Faculty of Medicine, Tanta University, Tanta 31511, Egypt., AboEl-Magd GH; Chest Diseases Department, Faculty of Medicine, Tanta University, Tanta 31511, Egypt., Ghalwash AA; Medical Biochemistry Department, Faculty of Medicine, Tanta University, Tanta 31511, Egypt.

Publikováno v: Antioxidants (Basel, Switzerland) [Antioxidants (Basel)] 2024 Apr 20; Vol. 13 (4). Date of Electronic Publication: 2024 Apr 20.