Zobrazeno 1 - 10
of 294
pro vyhledávání: '"Shakur Haleema"'
Autor:
Dewan Yashbir, Komolafe Edward O, Mejía-Mantilla Jorge H, Perel Pablo, Roberts Ian, Shakur Haleema
Publikováno v:
Trials, Vol 13, Iss 1, p 87 (2012)
Abstract Background Worldwide, over 10 million people are killed or hospitalized because of traumatic brain injury each year. About 90% of deaths occur in low- and middle-income countries. The condition mostly affects young adults, and many experienc
Externí odkaz:
https://doaj.org/article/ad48c68a58ea47b2915c5c067aeee9da
Publikováno v:
BMC Emergency Medicine, Vol 12, Iss 1, p 3 (2012)
Abstract Background The CRASH-2 trial showed that early administration of tranexamic acid (TXA) safely reduces mortality in bleeding in trauma patients. Based on data from the CRASH-2 trial, global mortality data and a systematic literature review, w
Externí odkaz:
https://doaj.org/article/cf50db742108426ebd9a2b9b13394421
Autor:
Knight Rosemary, Free Caroline, Shakur Haleema, Treweek Shaun, McDonald Alison M, Speed Chris, Campbell Marion K
Publikováno v:
Trials, Vol 12, Iss 1, p 74 (2011)
Abstract Randomised controlled trials (RCTs) are generally regarded as the gold standard for evaluating health care interventions. The level of uncertainty around a trial's estimate of effect is, however, frequently linked to how successful the trial
Externí odkaz:
https://doaj.org/article/4eb52fb42c404f48b89e39cc6dd78486
Autor:
Stocchetti Nino, Murray Gordon D, Harris Bridget A, Mascia Luciana, Citerio Giuseppe, Polderman Kees H, Battison Claire G, Sinclair Helen, Andrews Peter JD, Menon David K, Shakur Haleema, De Backer Daniel
Publikováno v:
Trials, Vol 12, Iss 1, p 8 (2011)
Abstract Background Traumatic brain injury is a major cause of death and severe disability worldwide with 1,000,000 hospital admissions per annum throughout the European Union. Therapeutic hypothermia to reduce intracranial hypertension may improve p
Externí odkaz:
https://doaj.org/article/81792bb03fb0430c971251e0178623cf
Publikováno v:
Trials, Vol 11, Iss 1, p 78 (2010)
Abstract Managing clinical trials, of whatever size and complexity, requires efficient trial management. Trials fail because tried and tested systems handed down through apprenticeships have not been documented, evaluated or published to guide new tr
Externí odkaz:
https://doaj.org/article/8854278b3a9d40a6905181f2121a6aee
Autor:
Allen Elizabeth, Ronsmans Carine, Alfirevic Zarko, Gülmezoglu Metin, Elbourne Diana, Shakur Haleema, Roberts Ian
Publikováno v:
Trials, Vol 11, Iss 1, p 40 (2010)
Abstract Background Each year, worldwide about 530,000 women die from causes related to pregnancy and childbirth. Of the deaths 99% are in low and middle income countries. Obstetric haemorrhage is the leading cause of maternal mortality, most occurri
Externí odkaz:
https://doaj.org/article/b5e6e9fae968405fbc2dac6cd0cb02dc
Publikováno v:
Cost Effectiveness and Resource Allocation, Vol 8, Iss 1, p 1 (2010)
Abstract Background The identification of safe and effective alternatives to blood transfusion is a public health priority. In sub-Saharan Africa, blood shortage is a cause of mortality and morbidity. Blood transfusion can also transmit viral infecti
Externí odkaz:
https://doaj.org/article/61a58a686e044ac4a10b522df496ce50
Autor:
Shakur Haleema, Roberts Ian
Publikováno v:
Trials, Vol 10, Iss 1, p 111 (2009)
Abstract A response to the letter regarding The BRAIN TRIAL: a randomized, placebo controlled trial of a Bradykinin B2 receptor antagonist (Anatibant) in patients with traumatic brain injury, by Mr Vincent Simmon President and CEO of Xytis Inc.
Externí odkaz:
https://doaj.org/article/4c9e8d033c86456f99d5a4f944509c79
Autor:
Rätsep Indrek, Ravi Ramalingam R, Pachl Jan, Murillo-Cabezas Francisco, Mantilla Jorge, Hartzenberg Bennie, Frost Chris, Fletcher Olivia, Druwé Patrick, Dewan Yashbir, Quintero Juan, Boeriu Cristian, Balica Laura, Asser Toomas, Andrews Peter, Shakur Haleema, Sampaio Cristina, Singh Manmohan, Svoboda Petr, Roberts Ian
Publikováno v:
Trials, Vol 10, Iss 1, p 109 (2009)
Abstract Background Cerebral oedema is associated with significant neurological damage in patients with traumatic brain injury. Bradykinin is an inflammatory mediator that may contribute to cerebral oedema by increasing the permeability of the blood-
Externí odkaz:
https://doaj.org/article/c3d3cc45c140435c900e57d054bb0965
Publikováno v:
BMC Pregnancy and Childbirth, Vol 9, Iss 1, p 29 (2009)
Abstract Background Post partum haemorrhage is a leading cause of maternal death worldwide. It also contributes to maternal morbidity as women may require a hysterectomy to control bleeding, or may require a blood transfusion, which can transmit vira
Externí odkaz:
https://doaj.org/article/ab0ac3f3cd664adf9bea52ab42c4244a