Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Shakti Ranjan, Satapathy"'
Autor:
Geriolda Topi, Shakti Ranjan Satapathy, Souvik Ghatak, Karin Hellman, Fredrik Ek, Roger Olsson, Roy Ehrnström, Marie-Louise Lydrup, Anita Sjölander
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-5 (2024)
Externí odkaz:
https://doaj.org/article/5df1f30bb958432f8f975e172fc6bdd9
Autor:
Geriolda Topi, Shakti Ranjan Satapathy, Souvik Ghatak, Karin Hellman, Fredrik Ek, Roger Olsson, Roy Ehrnström, Marie-Louise Lydrup, Anita Sjölander
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract In normal colon tissue, oestrogen receptor alpha (ERα) is expressed at low levels, while oestrogen receptor beta (ERβ) is considered the dominant subtype. However, in colon carcinomas, the ERα/β ratio is often increased, an observation t
Externí odkaz:
https://doaj.org/article/9909d49bdbe2475eb75229dbd8eb2454
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Immunotherapy targeting programmed death-ligand 1 (PD-L1) or PD-1 in solid tumors has been shown to be clinically beneficial. However, in colorectal cancer (CRC), only a subset of patients benefit from PD-1/PD-L1 treatment. Previously, we sh
Externí odkaz:
https://doaj.org/article/6e1c476837c84227ba971e19dda7f17c
Autor:
Geriolda Topi, Souvik Ghatak, Shakti Ranjan Satapathy, Roy Ehrnström, Marie-Louise Lydrup, Anita Sjölander
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
We reported that high estrogen receptor beta (ERβ) expression is independently associated with better prognosis in female colorectal cancer (CRC) patients. However, estrogen receptor alpha (ERα) is expressed at very low levels in normal colon mucos
Externí odkaz:
https://doaj.org/article/cc57e3759c6b4ea1b26b6a33b0285576
Autor:
Xiao-Feng Zheng, Sanket S. Acharya, Katherine N. Choe, Kumar Nikhil, Guillaume Adelmant, Shakti Ranjan Satapathy, Samanta Sharma, Keith Viccaro, Sandeep Rana, Amarnath Natarajan, Peter Sicinski, Jarrod A. Marto, Kavita Shah, Dipanjan Chowdhury
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Regulation of post translational modification of 53BP1 is critical for genome integrity and regulation of DNA damage response. Here the authors reveal a CDK5-PP4 phospho-signaling cascade that leads 53BP1 to sites of DNA damage.
Externí odkaz:
https://doaj.org/article/2c564c99951247baadb473f227a8cb95
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 4
Pages: 3409
Volume 24
Issue 4
Pages: 3409
Colorectal cancer (CRC), one of the leading causes of cancer-related deaths in the western world, is the third most common cancer for both men and women. As a heterogeneous disease, colon cancer (CC) is caused by both genetic and epigenetic changes.
Autor:
Roger Olsson, Pujarini Dash, Karin Hellman, Lubna M. Mehdawi, Souvik Ghatak, Shakti Ranjan Satapathy, Anita Sjölander, Fredrik Ek, Geriolda Topi
Publikováno v:
British Journal of Cancer. 126:586-597
Background Despite intense research, the prognosis for patients with advanced colorectal cancer (CRC) remains poor. The prostaglandin D2 receptors DP1 and DP2 are explored here as potential therapeutic targets for advanced CRC. Methods A CRC cohort w
Publikováno v:
Cancers; Volume 14; Issue 24; Pages: 6077
Treatment of melanoma with a BRAF inhibitor (BRAFi) frequently initiates development of BRAFi resistance, leading to increased tumor progression and metastasis. Previously, we showed that combined inhibition of elevated WNT5A and IL-6 signaling reduc
Autor:
Vikas, Yadav, Njainday, Jobe, Shakti Ranjan, Satapathy, Purusottam, Mohapatra, Tommy, Andersson
Publikováno v:
Cancers. 14(24)
Treatment of melanoma with a BRAF inhibitor (BRAFi) frequently initiates development of BRAFi resistance, leading to increased tumor progression and metastasis. Previously, we showed that combined inhibition of elevated WNT5A and IL-6 signaling reduc
Autor:
Sjölander, Souvik Ghatak, Syrina F. Mehrabi, Lubna M. Mehdawi, Shakti Ranjan Satapathy, Anita
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 793
Colorectal cancer (CRC) is one of the leading causes of cancer-related mortality worldwide. The current TNM (Tumor, Node, and Metastasis) classification approach is suboptimal in determining the prognosis of CRC patients. The prognosis for CRC is aff