Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Shakshi Patel"'
Autor:
Joshua B. Simpson, Josh J. Sekela, Benjamin S. Carry, Violet Beaty, Shakshi Patel, Matthew. R. Redinbo
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTProdrugs reliant on microbial activation are widely used but exhibit a range of efficacies that remain poorly understood. The anti-inflammatory compound 5-aminosalicylic acid (5-ASA), which is packaged in a variety of azo-linked prodrugs prov
Externí odkaz:
https://doaj.org/article/3cf8ac808cc94666b68e288131100d7c
Autor:
Matthew H. Foley, Morgan E. Walker, Allison K. Stewart, Sarah O’Flaherty, Emily C. Gentry, Shakshi Patel, Violet V. Beaty, Garrison Allen, Meichen Pan, Joshua B. Simpson, Caroline Perkins, Molly E. Vanhoy, Michael K. Dougherty, Sarah K. McGill, Ajay S. Gulati, Pieter C. Dorrestein, Erin S. Baker, Matthew R. Redinbo, Rodolphe Barrangou, Casey M. Theriot
Publikováno v:
Nature Microbiology. 8:611-628
Bile acids (BAs) mediate the crosstalk between human and microbial cells and influence diseases including Clostridioides difficile infection (CDI). While bile salt hydrolases (BSHs) shape the BA pool by deconjugating conjugated BAs, the basis for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce715db0f0bb873b374a9d5021ef94ef
https://doi.org/10.1038/s41564-023-01337-7
https://doi.org/10.1038/s41564-023-01337-7
Autor:
Joshua B. Simpson, Josh J. Sekela, Benjamin S. Carry, Violet Beaty, Shakshi Patel, Matthew. R. Redinbo
Background: Prodrugs reliant on microbial activation are widely used but exhibit a range of efficacies that remain poorly understood. The anti-inflammatory compound 5-aminosalicylic acid (5-ASA), which is packaged in a variety of azo-linked prodrugs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56be7714c6b04ec44dcd5955399ef55f
https://doi.org/10.21203/rs.3.rs-2326828/v1
https://doi.org/10.21203/rs.3.rs-2326828/v1
Autor:
Matthew H. Foley, Morgan E. Walker, Allison K. Stewart, Sarah O’Flaherty, Emily C. Gentry, Garrison Allen, Shakshi Patel, Meichen Pan, Violet V. Beaty, Molly E. Vanhoy, Michael K. Dougherty, Sarah K. McGill, Ajay Gulati, Pieter C. Dorrestein, Erin S. Baker, Matthew R. Redinbo, Rodolphe Barrangou, Casey M. Theriot
Summary paragraphBile acids (BAs) mediate the crosstalk between human and microbial cells and influence intestinal diseases including Clostridioides difficile infection (CDI). While bile salt hydrolases (BSHs) shape the BA pool by deconjugating conju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d9196a319b6dfca254dadb635f99aae
https://doi.org/10.1101/2022.03.24.485529
https://doi.org/10.1101/2022.03.24.485529