PTEN regulates expression of its pseudogene in glioblastoma cells in DNA methylation-dependent manner.

Autor: Kovalenko TF; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia., Yadav B; Amity Institute of Biotechnology, Amity University Haryana, Panchgaon, Manesar, Haryana, India., Anufrieva KS; Laboratory of System Biology, Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, Moscow, Russia; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, Moscow, Russia., Larionova TD; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia., Aksinina TE; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia., Latyshev YA; Federal State Autonomous Institution, N.N. Burdenko National Medical Research Center of Neurosurgery, Moscow, Russia., Bastola S; Department of Bioengineering, University of California Los Angeles, Los Angeles, CA, USA., Shakhparonov MI; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia., Pandey AK; Amity Institute of Biotechnology, Amity University Haryana, Panchgaon, Manesar, Haryana, India; National Institute of Pharmaceutical Education and Research, Palaj, Gandhinagar, Gujarat, India., Pavlyukov MS; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia. Electronic address: marat.pav@mail.ru.

Publikováno v: Biochimie [Biochimie] 2024 Apr; Vol. 219, pp. 74-83. Date of Electronic Publication: 2023 Aug 22.

Dual targeting of DR5 and VEGFR2 molecular pathways by multivalent fusion protein significantly suppresses tumor growth and angiogenesis.

Autor: Isakova AA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, 117997 Moscow, Russia; Faculty of Biology, Lomonosov Moscow State University, 119192 Moscow, Russia., Artykov AA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, 117997 Moscow, Russia., Plotnikova EA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, 117997 Moscow, Russia; P.А. Hertsen Moscow Oncology Research Institute - branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation, 125284 Moscow, Russia., Trunova GV; P.А. Hertsen Moscow Oncology Research Institute - branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation, 125284 Moscow, Russia., Khokhlova VА; P.А. Hertsen Moscow Oncology Research Institute - branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation, 125284 Moscow, Russia., Pankratov AA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, 117997 Moscow, Russia; P.А. Hertsen Moscow Oncology Research Institute - branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation, 125284 Moscow, Russia., Shuvalova ML; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, 117997 Moscow, Russia; Laboratory of Synthetic Neurotechnologies, Pirogov Russian National Research Medical University, 117997 Moscow, Russia., Mazur DV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, 117997 Moscow, Russia; Faculty of Biology, Lomonosov Moscow State University, 119192 Moscow, Russia., Antipova NV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, 117997 Moscow, Russia., Shakhparonov MI; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, 117997 Moscow, Russia., Dolgikh DA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, 117997 Moscow, Russia; Faculty of Biology, Lomonosov Moscow State University, 119192 Moscow, Russia., Kirpichnikov MP; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, 117997 Moscow, Russia; Faculty of Biology, Lomonosov Moscow State University, 119192 Moscow, Russia., Gasparian ME; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, 117997 Moscow, Russia; Manebio LLC, 115280 Moscow, Russia. Electronic address: marine_gasparian@yahoo.com., Yagolovich AV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, 117997 Moscow, Russia; Faculty of Biology, Lomonosov Moscow State University, 119192 Moscow, Russia; Manebio LLC, 115280 Moscow, Russia. Electronic address: anneyagolovich@gmail.com.

Publikováno v: International journal of biological macromolecules [Int J Biol Macromol] 2024 Jan; Vol. 255, pp. 128096. Date of Electronic Publication: 2023 Nov 14.

Interactome of Paraoxonase PON2 Reveals New Pathways for Tumor Growth Regulation.

Autor: Karlov VD; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia.; All-Russia Research Institute of Agricultural Biotechnology, Moscow, Russia., Pestov NB; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia.; Moscow Institute of Physics and Technology, Dolgoprudny, Russia.; Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences, Moscow, Russia.; Institute of Biomedical Chemistry, Moscow, Russia., Shakhparonov MI; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia., Korneenko TV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia. tvkorn@gmail.com.

Publikováno v: Doklady. Biochemistry and biophysics [Dokl Biochem Biophys] 2023 Feb; Vol. 508 (1), pp. 31-36. Date of Electronic Publication: 2023 Jan 18.

Alternative RNA splicing modulates ribosomal composition and determines the spatial phenotype of glioblastoma cells.

Autor: Larionova TD; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russian Federation., Bastola S; Department of Bioengineering, University of California Los Angeles, Los Angeles, CA, USA., Aksinina TE; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russian Federation., Anufrieva KS; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Federal Research and Clinical Center of Physical-Chemical Medicine, Federal Medical Biological Agency, Moscow, Russian Federation.; Federal Research and Clinical Center of Physical-Chemical Medicine, Federal Medical and Biological Agency, Moscow, Russian Federation., Wang J; Department of Neurosurgery, Centre of Brain Science, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China., Shender VO; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russian Federation.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Federal Research and Clinical Center of Physical-Chemical Medicine, Federal Medical Biological Agency, Moscow, Russian Federation.; Federal Research and Clinical Center of Physical-Chemical Medicine, Federal Medical and Biological Agency, Moscow, Russian Federation., Andreev DE; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russian Federation.; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russian Federation., Kovalenko TF; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russian Federation., Arapidi GP; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russian Federation.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Federal Research and Clinical Center of Physical-Chemical Medicine, Federal Medical Biological Agency, Moscow, Russian Federation.; Federal Research and Clinical Center of Physical-Chemical Medicine, Federal Medical and Biological Agency, Moscow, Russian Federation., Shnaider PV; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Federal Research and Clinical Center of Physical-Chemical Medicine, Federal Medical Biological Agency, Moscow, Russian Federation.; Federal Research and Clinical Center of Physical-Chemical Medicine, Federal Medical and Biological Agency, Moscow, Russian Federation., Kazakova AN; Federal Research and Clinical Center of Physical-Chemical Medicine, Federal Medical and Biological Agency, Moscow, Russian Federation., Latyshev YA; N.N. Burdenko National Medical Research Center of Neurosurgery, Ministry of Health of the Russian Federation, Moscow, Russian Federation., Tatarskiy VV; Institute of Gene Biology, Russian Academy of Sciences, Moscow, Russian Federation., Shtil AA; Blokhin National Medical Research Center of Oncology, Moscow, Russian Federation., Moreau P; Institute of Chemistry of Clermont-Ferrand, CNRS, Université Clermont Auvergne, Clermont-Ferrand, France., Giraud F; Institute of Chemistry of Clermont-Ferrand, CNRS, Université Clermont Auvergne, Clermont-Ferrand, France., Li C; Department of Neurosurgery, School of Medicine and O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA., Wang Y; Department of Neurosurgery, Centre of Brain Science, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China., Rubtsova MP; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russian Federation.; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russian Federation., Dontsova OA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russian Federation.; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russian Federation.; Center of Life Sciences, Skolkovo Institute of Science and Technology, Moscow, Russian Federation., Condro M; Department of Bioengineering, University of California Los Angeles, Los Angeles, CA, USA., Ellingson BM; Brain Tumor Imaging Laboratory, Center for Computer Vision and Imaging Biomarkers, University of California Los Angeles, Los Angeles, CA, USA.; Department of Radiological Sciences, University of California Los Angeles, Los Angeles, CA, USA.; Department of Psychiatry, University of California Los Angeles, Los Angeles, CA, USA.; Department of Neurosurgery, University of California Los Angeles, Los Angeles, CA, USA., Shakhparonov MI; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russian Federation., Kornblum HI; Intellectual and Developmental Disabilities Research Center, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA., Nakano I; Department of Neurosurgery, Medical Institute of Hokuto, Hokkaido, Japan. ichironakano1369@gmail.com., Pavlyukov MS; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russian Federation. marat.pav@mail.ru.; Centre for Genomic Regulation, Barcelona Institute of Science and Technology, Barcelona, Spain. marat.pav@mail.ru.

Publikováno v: Nature cell biology [Nat Cell Biol] 2022 Oct; Vol. 24 (10), pp. 1541-1557. Date of Electronic Publication: 2022 Oct 03.

The Prognostic Significance of Spliceosomal Proteins for Patients with Glioblastoma.

Autor: Larionova TD; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia., Kovalenko TF; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia., Shakhparonov MI; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia., Pavlyukov MS; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia. marat.pav@mail.ru.

Publikováno v: Doklady. Biochemistry and biophysics [Dokl Biochem Biophys] 2022 Apr; Vol. 503 (1), pp. 71-75. Date of Electronic Publication: 2022 May 10.