Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Shajjia Razi"'
SIRT1 Polymorphisms and Serum-Induced SIRT1 Protein Expression in Aging and Frailty: The CHAMP Study
Autor:
Shajjia Razi, Robert G. Cumming, David G. Le Couteur, Marina L. Kennerson, Vicky L. Benson, Rafael de Cabo, Aisling C. McMahon, Victoria C. Cogger, David J. Handelsman, Vasikaran Naganathan, Louise M. Waite, Vasant Hirani, Markus J. Seibel, Fiona M. Blyth
Publikováno v:
The journals of gerontology. Series A, Biological sciences and medical sciences. 72(7)
The nutrient sensing protein, SIRT1 influences aging and nutritional interventions such as caloric restriction in animals, however, the role of SIRT1 in human aging remains unclear. Here, the role of SIRT1 single-nucleotide polymorphisms (SNPs) and s
Autor:
Shahid Abbas, Nicole Soranzo, Nabi Shah, Muhammed Murtaza, Nadeem Hayat Mallick, Jawaid Hassan Niazi, Muhammad Salman Daood, Sarah L. Bray, Kishore Kumar, Stephen Kaptoge, Tanja B. Grammer, Ralph McGinnis, Adam S. Butterworth, Muhammad Azhar, Marcus E. Kleber, Syed Saadat Ali, Faisal Shahid, Willem H. Ouwehand, Moazzam Zaidi, Muhammad Ishaq, Simon C. Potter, Frank Dudbridge, Mustafa Hussain, Danish Saleheen, Shahzad Majeed Bhatti, Gurdeep S. Sagoo, Hubert Scharnagl, Kerstin Koch, Zia Yaqoob, Wilfried Renner, Simon G. Thompson, Abdus Samad, Aftab Alam Gul, Abdul Hakeem, Michael M. Hoffmann, Suzanna Bumpstead, Maria Samuel, Asim Saleem, Asif Rasheed, Usman Ahmad, Nasir Sheikh, Alexander M. W. Cargill Thompson, Myriam Alexander, Emanuele Di Angelantonio, Fazal-ur Rehman, Ali Raza Gardezi, Reeta Gobin, Nadeem Sarwar, Rashid Jooma, J. Stephens, Assadullah Kundi, Philippe M. Frossard, Khan Shah Zaman, Winfried März, Kishwar Kumar, Michael Inouye, Shajjia Razi Haider, Sarah E. Hunt, Nadeem Qamar, Fahim Muhammad, Panos Deloukas, Liaquat Ali Cheema, Anthony Attwood, Azhar Faruqui, Junaid Zafar, Syed Zahed Rasheed, Abdul Ghaffar, Bernhard O. Boehm, Rhian Gwilliam, Bernhard R. Winkelmann, John Danesh, Philip Haycock, Nazir Ahmed Memon
Publikováno v:
Circulation: Cardiovascular Genetics. 3:348-357
Background— Evidence is sparse about the genetic determinants of major lipids in Pakistanis. Methods and Results— Variants (n=45 000) across 2000 genes were assessed in 3200 Pakistanis and compared with 2450 Germans using the same gene array and
Autor:
Usman Ahmad, Danish Saleheen, Hamza Khalid, Aisha Nazir, Kamran Shahid, Shaheen Khanum, Aisha Habib, Philippe M. Frossard, Imad Hussain, Fahad Shuja, Shajjia Razi Haider
Publikováno v:
International Journal of Cardiology. 115:7-13
Background and objectives ATP-binding cassette transporter 1 ( ABCA1 ) is a trans-membrane protein responsible for the efflux of cholesterol and phospholipids across the cell membrane, an essential step in the reverse cholesterol transport system. Th
Autor:
Stephen Kaptoge, Kishwar Kumar, Muhammad Azhar, Abdus Samad, Shajjia Razi Haider, Adam S. Butterworth, Nadeem Qamar, Syed Saadat Ali, Moazzam Zaidi, Zia Yaqoob, Shahzad Majeed Bhatti, Nabi Shah, Maria Samuel, Asim Saleem, Emma Gray, Simon C. Potter, Shahid Abbas, Usman Ahmad, Faisal Shahid, Muhammad Ali Memon, David Wormser, Nicole Soranzo, Zehra Memon, Hannah Blackburn, Fatima Memon, Waleed T. Kayani, Myriam Alexander, Muhammed Murtaza, Abdul Hakeem, Assadullah Kundi, Khan Shah Zaman, Junaid Zafar, Nadeem Hayat Mallick, Muhammad Ishaq, Azhar Faruqui, Nasir Sheikh, Suzannah Bumpstead, Naomi Hammond, Philippe M. Frossard, Fazal-ur-Rehman Memon, Panos Deloukas, Liaquat Ali Cheema, Kishore Kumar, Mustafa Hussain, Danish Saleheen, Ali Raza Gardezi, Asif Rasheed, Aftab Alam Gul, Emanuele Di Angelantonio, Rashid Jooma, Syed Zahed Rasheed, Abdul Ghaffar, Muhammad Fahim, John Danesh, Philip Haycock, Ahmedyar Janjua, Nazir Ahmed Memon, Jawaid Hassan Niazi, Muhammad Salman Daood
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 30(7)
Objective— To examine variants at the 9p21 locus in a case-control study of acute myocardial infarction (MI) in Pakistanis and to perform an updated meta-analysis of published studies in people of European ancestry. Methods and Results— A total o
Autor:
Shajjia Razi Haider, Saad Shafqat, Shaheen Khanum, M. Kashif Anis, Danish Saleheen, Aisha Nazir, Shabbar Bukhari, Philippe M. Frossard
Publikováno v:
Stroke. 36(10)
Background and Objectives— Identification of STRK1 locus by the deCODE group followed by the discovery of phosphodiesterase 4D ( PDE4D ) gene in strong association with ischemic stroke patients has provided useful insights toward understanding the
Publikováno v:
International Journal of Cardiology. 110:259-260
Low levels of high density lipoprotein-cholesterol (HDL-C) is an established risk factor for cardiovascular disorders and is independent of LDL and total cholesterol concentration in predicting the risk of disease [1]. The protective effect of HDL-C
Akademický článek
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Akademický článek
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Publikováno v:
Canadian Medical Association Journal. 173:578.3-579
Pantothenate kinase–associated neurodegeneration is an autosomal recessive disorder characterized by accumulation of iron mainly in the basal ganglia.[1][1],[2][2] In about half of these cases, patients have an identifiable mutation in the PANK2 ge
Autor:
Saleheen D, Bukhari S, Haider SR, Nazir A, Khanum S, Shafqat S, Anis MK, Frossard P, Saleheen, Danish, Bukhari, Shabbar, Haider, Shajjia Razi, Nazir, Aisha, Khanum, Shaheen, Shafqat, Saad, Anis, M Kashif, Frossard, Philippe
Publikováno v:
Stroke (00392499); 2005 Oct, Vol. 36 Issue 10, p2275-2277, 3p