Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Shaishav Dhage"'
Autor:
Bethanie Garside, Jan Hoong Ho, See Kwok, Yifen Liu, Shaishav Dhage, Rachelle Donn, Zohaib Iqbal, Simon A. Jones, Handrean Soran
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-7 (2021)
Abstract Background Enzyme replacement therapy (ERT) with olipudase alfa, a recombinant human acid sphingomyelinase (rhASM), is being developed to treat patients with ASM deficiency (ASMD), commonly known as Niemann–Pick disease (NPD) types A or B.
Externí odkaz:
https://doaj.org/article/b7dc6ce787a046a7879d994e777be5c2
Autor:
Shaishav Dhage, Maryam Ferdousi, Safwaan Adam, Jan Hoong Ho, Alise Kalteniece, Shazli Azmi, Uazman Alam, Georgios Ponirakis, Ioannis Petropoulos, Andrew J. Atkinson, Andrew Marshall, Maria Jeziorska, Handrean Soran, Rayaz A. Malik
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Accurately quantifying the progression of diabetic peripheral neuropathy is key to identify individuals who will progress to foot ulceration and to power clinical intervention trials. We have undertaken detailed neuropathy phenotyping to ass
Externí odkaz:
https://doaj.org/article/6e4fe82f035548e3b5afb9e01bf828a9
Autor:
Jan Hoong Ho, Kwok Leung Ong, Luisa F. Cuesta Torres, Yifen Liu, Safwaan Adam, Zohaib Iqbal, Shaishav Dhage, Basil J. Ammori, Akheel A. Syed, Kerry-Anne Rye, Fatiha Tabet, Handrean Soran
Publikováno v:
Journal of Lipid Research, Vol 62, Iss , Pp 100043- (2021)
Roux-en-Y gastric bypass (RYGB) is one of the most commonly performed weight-loss procedures, but how severe obesity and RYGB affect circulating HDL-associated microRNAs (miRNAs) remains unclear. Here, we aim to investigate how HDL-associated miRNAs
Externí odkaz:
https://doaj.org/article/a66adb2a592b4cd09d4d075da4578600
Autor:
Giuseppe Lauria, Catharina G Faber, Andrew Marshall, Georgios Ponirakis, Ioannis N Petropoulos, Uazman Alam, Rayaz A Malik, Handrean Soran, Maryam Ferdousi, Alise Kalteniece, Shazli Azmi, Anne Worthington, Luca D'Onofrio, Shaishav Dhage
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 8, Iss 2 (2020)
Introduction Diabetic neuropathy can be diagnosed and assessed using a number of techniques including corneal confocal microscopy (CCM).Research design and methods We have undertaken quantitative sensory testing, nerve conduction studies and CCM in 1
Externí odkaz:
https://doaj.org/article/459f644de6974825964c72142816af05
Autor:
Anne Worthington, Alise Kalteniece, Maryam Ferdousi, Luca D’Onofrio, Shaishav Dhage, Shazli Azmi, Clare Adamson, Shaheen Hamdy, Rayaz A. Malik, Nigel A. Calcutt, Andrew G. Marshall
Publikováno v:
Diagnostics, Vol 11, Iss 7, p 1247 (2021)
Impaired rate-dependent depression of the Hoffman reflex (HRDD) is a potential biomarker of impaired spinal inhibition in patients with painful diabetic neuropathy. However, the optimum stimulus-response parameters that identify patients with spinal
Externí odkaz:
https://doaj.org/article/b9484533c7384c32a5976567f7629a19
Autor:
Rahul Yadav, Salam Hama, Yifen Liu, Tarza Siahmansur, Jonathan Schofield, Akheel A. Syed, Michael France, Philip Pemberton, Safwaan Adam, Jan Hoong Ho, Reza Aghamohammadzadeh, Shaishav Dhage, Rachelle Donn, Rayaz A. Malik, John P. New, Maria Jeziorska, Paul Durrington, Basil A. Ammori, Handrean Soran
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
PurposeObesity is a major modifiable risk factor for cardiovascular disease. Bariatric surgery is considered to be the most effective treatment option for weight reduction in obese patients with and without type 2 diabetes (T2DM).ObjectiveTo evaluate
Externí odkaz:
https://doaj.org/article/072fb210cd494a048a892c11a31070c4
Autor:
Shawg Ganawa, Chiedza Mashamba, Waqas Ilyas, Claire Higham, Tim Cooksley, Ho Jan Hoong, Safwaan Adam, Shaishav Dhage
Publikováno v:
Endocrine Abstracts.
Autor:
Zohaib Iqbal, Bilal Bashir, Safwaan Adam, Jan H. Ho, Shaishav Dhage, Shazli Azmi, Maryam Ferdousi, Zahid Yusuf, Rachelle Donn, Rayaz A. Malik, Akheel Syed, Basil J. Ammori, Adrian Heald, Paul N. Durrington, Handrean Soran
Publikováno v:
Atherosclerosis. 346:10-17
The causal relationship between LDL cholesterol (LDL-C) and the pathogenesis of atherosclerosis is well established. Previous studies have shown that modifications, glycation and oxidation of LDL enhance its atherogenic potential. Glycation of LDL oc
Autor:
Anne Marshall, Alise Kalteniece, Maryam Ferdousi, Shazli Azmi, Edward B Jude, Clare Adamson, Luca D’Onofrio, Shaishav Dhage, Handrean Soran, Jackie Campbell, Corinne A Lee-Kubli, Shaheen Hamdy, Rayaz A Malik, Nigel A Calcutt, Andrew G Marshall
Publikováno v:
Brain communications, vol 5, iss 2
The dominant sensory phenotype in patients with diabetic polyneuropathy and neuropathic pain is a loss of function. This raises questions as to which mechanisms underlie pain generation in the face of potentially reduced afferent input. One potential
Autor:
Shawg Ganawa, Haris Muhammad, Tom Knight, Shaishav Dhage, Ho Jan Hoong, Avinash Gupta, Paul Lorigan, Claire Higham, Tim Cooksley, Safwaan Adam
Publikováno v:
Endocrine Abstracts.