Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Shaimaa Waz"'
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Hydrogen sulfide (H2S) is an endogenously gas transmitter signaling molecule with known antioxidant, anti-inflammatory, and cytoprotective properties. Although accumulating evidence shows the therapeutic potential of H2S in various hepatic diseases,
Externí odkaz:
https://doaj.org/article/fe8f8f1f224543049482d90c1272bf95
Autor:
Ahmed M. Fathi, Shaimaa Waz, Eman Alaaeldin, Nisreen D. M. Toni, Azza A. K. El-Sheikh, Ahmed M. Sayed, Usama Ramadan Abdelmohsen, Maiiada H. Nazmy
Publikováno v:
Metabolites, Vol 13, Iss 3, p 419 (2023)
Liver ischemia-reperfusion injury (IRI) is a pathophysiological insult that often occurs during liver surgery. Blackberry leaves are known for their anti-inflammatory and antioxidant activities. Aims: To achieve site-specific delivery of blackberry l
Externí odkaz:
https://doaj.org/article/070a649936484b3faeeead3b686ac0d1
Autor:
Hany Ezzat Khalil, Miada F. Abdelwahab, Hairul-Islam Mohamed Ibrahim, Khalid A. AlYahya, Abdullah Abdulhamid Altaweel, Abdullah Jalal Alasoom, Hussein Ali Burshed, Marwan Mohamed Alshawush, Shaimaa Waz
Publikováno v:
Life, Vol 12, Iss 11, p 1731 (2022)
Metabolic dysfunctions linked to obesity carry the risk of co-morbidities such as diabetes, hepatorenal, and cardiovascular diseases. Coumarins are believed to display several biological effects on diverse adverse health conditions. This study was co
Externí odkaz:
https://doaj.org/article/ac6afb208dbf4e7b97bf8f0f1da2e9e0
Autor:
Hany Ezzat Khalil, Miada F. Abdelwahab, Hairul-Islam Mohamed Ibrahim, Khalid A. AlYahya, Ahmed Adel Mohamed, Amira Samir Radwan, Shaimaa Waz
Publikováno v:
Molecules, Vol 27, Iss 21, p 7192 (2022)
Type 2 diabetes mellitus is considered to be a substantial socioeconomic burden worldwide on both patients and governments. Coumarins are biomolecules with a diversity of biological activities. The current investigation aimed to explore the ameliorat
Externí odkaz:
https://doaj.org/article/d940c3dc5b1d4e6ca67720e632f5e6a5
Autor:
Asmaa I. Matouk, Shaimaa Waz
Publikováno v:
Toxicology Mechanisms and Methods. 32:194-203
Doxorubicin (DOX) is an effective anthracycline chemotherapeutic drug. Nevertheless, the cardiotoxicity adverse effect restricts its clinical benefit. Allyl isothiocyanate (AITC) is a natural antioxidant and anti-inflammatory agent. In the present st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f6e9cb5dedf70be9129e434cc0fbeec
https://doi.org/10.1080/15376516.2021.1992064
https://doi.org/10.1080/15376516.2021.1992064
Autor:
Yasmine F. Ibrahim, Somaia Hassan Hammady, Rehab A. Rifaai, Shaimaa Waz, Mohamed Abdellah Ibrahim, Heba M. Hafez
Publikováno v:
Chemico-biological interactions. 366
Gentamicin (GEN) possesses a broad range of antimicrobial effects. However, it belongs to the aminoglycosides, and has the greatest potential for nephrotoxic effect above all other antibiotics from this group. This study aims to evaluate the possible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a84085a653f19fa0811fc1aa5b3b07ef
https://pubmed.ncbi.nlm.nih.gov/36057361
https://pubmed.ncbi.nlm.nih.gov/36057361
Publikováno v:
Life sciences. 294
Aprepitant, a neurokinin-1 (NK1) receptor antagonist, is a clinically approved anti-emetic drug. Recently, inhibition of the NK1 receptor has been reported as a potential nephroprotective strategy. We aimed to assess the pharmacological mechanisms of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed1fe3b73ef849df196c14d4fb90b842
https://pubmed.ncbi.nlm.nih.gov/35143828
https://pubmed.ncbi.nlm.nih.gov/35143828
Publikováno v:
Toxicology and Applied Pharmacology. 457:116313
Cadmium (Cd) has potential hazards on human beings. Consequently, this study was performed to explore the protective effects of agomelatine (AGO), a melatonin receptor agonist, against Cd-induced toxicity in rats. AGO (40 mg/kg/day) was administered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::effaaae3716c32af41e6783abd3686ba
https://doi.org/10.1016/j.taap.2022.116313
https://doi.org/10.1016/j.taap.2022.116313
Publikováno v:
Biomedicine & Pharmacotherapy. 155:113752
The anticancer drug methotrexate (MTX) is known to cause hepatotoxicity as a possibly fatal adverse effect that hinders its clinical application. Although the natural flavonoid, dihydromyricetin (DHM), has antioxidant and anti-inflammatory effects; i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea2ddc3b6aa55326772e8e6d1e128da2
https://doi.org/10.1016/j.biopha.2022.113752
https://doi.org/10.1016/j.biopha.2022.113752
Autor:
Teruya Nakamura, Shaimaa Waz, Shinji Ikemizu, Keisuke Hirata, Yusaku Nakabeppu, Yukari Koga-Ogawa, Takao Arimori, Yuriko Yamagata, Taro Tamada, Mami Chirifu
Publikováno v:
The Journal of Biological Chemistry
The human MutT homolog 1 (hMTH1, human NUDT1) hydrolyzes oxidatively damaged nucleoside triphosphates and is the main enzyme responsible for nucleotide sanitization. hMTH1 recently has received attention as an anticancer target because hMTH1 blockade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a3a5154fc83dab13e68446d28e0666b
https://doi.org/10.1074/jbc.m116.749713
https://doi.org/10.1074/jbc.m116.749713