Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Shaimaa S. Goher"'
Publikováno v:
Medicine in Drug Discovery, Vol 13, Iss , Pp 100114- (2022)
The mutations in the receptor binding domain (RBD) of the SARS-CoV-2 are shown to enhance its replication, transmissibility, and binding to host cells. Recently, a new strain is reported in India that includes mutations (T478K, and L452R) in the RBD,
Externí odkaz:
https://doaj.org/article/e163f37b3dc0418d85bc795e6f13e1f6
Publikováno v:
Nuclear Receptors ISBN: 9783030783143
Estrogen-related receptors (ERRs) are members of the nuclear hormone receptor (NR) superfamily. The ERR subfamily comprise three members, ERRα, ERRβ, and ERRγ. They are closely related to the estrogen receptors (ERα and ERβ), but unlike ER recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fcf1c015b5b5c8247d2478f91660a17
https://doi.org/10.1007/978-3-030-78315-0_5
https://doi.org/10.1007/978-3-030-78315-0_5
Autor:
Thomas P. Burris, Shaimaa S. Goher, Amer Avdagic, Lamees Hegazy, Ryan Sanders, Cyrielle Billon, Bahaa El-Dien M. El-Gendy, Sheryl L. Burris, Mohamed Elagawany, Sadichha Sitaula, Mohamed Shahien
Publikováno v:
Bioorg Chem
Estrogen Related Receptors (ERRs) are key regulators of energy homeostasis and play important role in the etiology of metabolic disorders, skeletal muscle related disorders, and neurodegenerative diseases. Among the three ERR isoforms, ERRα emerged
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84737a44749d551d3394324df3c42bd8
https://pubmed.ncbi.nlm.nih.gov/32683181
https://pubmed.ncbi.nlm.nih.gov/32683181
Publikováno v:
Journal of Medicinal Chemistry. 61:10935-10956
Nuclear hormone receptors represent a large family of ligand-activated transcription factors that include steroid receptors, thyroid/retinoid receptors, and orphan receptors. Among nuclear hormone receptors, the liver X receptors have emerged as very
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d361ae9d65745cc9ddb032f0fece666c
https://doi.org/10.1021/acs.jmedchem.8b00045
https://doi.org/10.1021/acs.jmedchem.8b00045
Autor:
Lamees Hegazy, Mohamed Elagawany, Thomas P. Burris, M. M. H. Arief, Kristine Griffett, Amer Avdagic, Subhashis Banerjee, Bahaa El-Dien M. El-Gendy, Shaimaa S. Goher
Publikováno v:
Bioorganicmedicinal chemistry letters. 29(3)
Liver X Receptor (LXR) agonists have been reported as a potential treatment for atherosclerosis, Alzheimer’s disease and hepatitis C virus (HCV) infection. We have designed and synthesized a series of potent compounds based on a 1,2,4-triazole scaf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0592022401b74b840c81396995bc56c1
https://pubmed.ncbi.nlm.nih.gov/30587446
https://pubmed.ncbi.nlm.nih.gov/30587446
Autor:
Bahaa El-Dien M, El-Gendy, Shaimaa S, Goher, Lamees S, Hegazy, Mohamed M H, Arief, Thomas P, Burris
Publikováno v:
Journal of medicinal chemistry. 61(24)
Nuclear hormone receptors represent a large family of ligand-activated transcription factors that include steroid receptors, thyroid/retinoid receptors, and orphan receptors. Among nuclear hormone receptors, the liver X receptors have emerged as very
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::47383b632d37bff00f325ea3b466fae7
https://pubmed.ncbi.nlm.nih.gov/30004226
https://pubmed.ncbi.nlm.nih.gov/30004226