Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Shaimaa N. Abd Alhammid"'
Publikováno v:
مجلة كلية الطب, Vol 66, Iss 2 (2024)
Background: Dutasteride, is a drug whose mechanism of action is inhibition of the enzyme 5-alpha reductase. It has been approved for use in the treatment of benign prostatic hyperplasia. Dutasteride has low solubility and high permeability, which cla
Externí odkaz:
https://doaj.org/article/a0f43defe8904454b17c1b31384faa03
Autor:
Shaimaa N. Abd Alhammid, Hanan J. Kassab, Lina S. Hussein, Mahmood A. Haiss, Hussein k. Alkufi
Publikováno v:
Ma’aen Journal for Medical Sciences, Vol 2, Iss 3 (2023)
Externí odkaz:
https://doaj.org/article/834eddd7bb81483094e44f485f3d7237
Publikováno v:
Iraqi Journal of Pharmaceutical Sciences, Vol 30, Iss 1, Pp 209-217 (2021)
Felodipine is a calcium-channel blocker with low aqueous solubility and bioavailability. Lipid dosage forms are attractive delivery systems for such hydrophobic drug molecules. Nanoemulsion (NE) is one of the popular methods that has been used to sol
Externí odkaz:
https://doaj.org/article/e82607b95ee24617a7f5b864dccec84d
Autor:
Ahmed H. Ali, Shaimaa N. Abd-Alhammid
Publikováno v:
Iraqi Journal of Pharmaceutical Sciences, Vol 28, Iss 2, Pp 46-57 (2019)
Atorvastatin have problem of very slightly aqueous solubility (0.1-1 mg/ml). Nano-suspension is used to enhance it’s of solubility and dissolution profile. The aim of this study is to formulate Atorvastatin as a nano-suspension to enhance its solub
Externí odkaz:
https://doaj.org/article/4be04c456ecb49e2982bf2e2b5fdeb39
Publikováno v:
Iraqi Journal of Pharmaceutical Sciences, Vol 29, Iss 2 (2020)
CD-nanosponges were prepared by crosslinking B-CD with diphenylcarbonate (DPC) using ultrasound assisted technique. 5-FU was incorporated with NS by freeze drying, and the phase solubility study, complexation efficiency (CE) entrapment efficiency wer
Externí odkaz:
https://doaj.org/article/b293b6249f884013910b47f31d65cc55
Publikováno v:
Iraqi Journal of Pharmaceutical Sciences, Vol 29, Iss 1 (2020)
Letrozole (LZL) is a non-steroidal competitive aromatase enzyme system inhibitor. The aim of this study is to improve the permeation of LZL through the skin by preparing as nanoemulsion using various numbers of oils, surfactants and co-surfactant wit
Externí odkaz:
https://doaj.org/article/4e59dd093cbd404ba68b81bcd31d9612
Publikováno v:
Pakistan Journal of Medical and Health Sciences. 16:789-794
Purpose: The objective of this research is to prepare cefdinir as a nanosuspension formulation to improve its solubility and dissolution rate. Cefdinir is a class IV drug with low solubility and low permeability. Methods: Eight formulations were prep
Publikováno v:
Iraqi Journal of Pharmaceutical Sciences, Vol 23, Iss 1, Pp 53-59 (2017)
Fast dissolving film can be defined as a dosage form, which when placed in the oral cavity. It will rapidly disintegrate and dissolves to release the medication for oral mucosal absorption or allow for the gastrointestinal absorption to be achieved w
Externí odkaz:
https://doaj.org/article/d538e6bdc9254ff9b2c8ca8b61ab1876
Publikováno v:
International journal of health sciences. :12154-12172
Cefdinir (Cef) is a third-generation cephalosporin antibacterial agent with an extended spectrum and low solubility and permeability. In this study, cefdinir was prepared as nanosuspension and lyophilized to powder. The lyophilized cefdinir was furth
Autor:
Yasser A.Ali, Shaimaa N. Abd-Alhammid
Publikováno v:
Iraqi Journal of Pharmaceutical Sciences, Vol 24, Iss 2 (2017)
The aim of this study is to formulate and evaluate ezetimibe nanoparticles using solvent antisolvent technology. Ezetimibe is a practically water-insoluble drug which acts as a lipid lowering drug that selectively inhibits the intestinal absorption o
Externí odkaz:
https://doaj.org/article/245a56e2258542e588bf2013e7ad6b74