Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Shaima Al Khabouri"'
Autor:
Shaima Al Khabouri, Robert A. Benson, Catriona T. Prendergast, Joshua I. Gray, Thomas D. Otto, James M. Brewer, Paul Garside
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Effective tolerogenic intervention in Rheumatoid Arthritis (RA) will rely upon understanding the evolution of articular antigen specific CD4 T cell responses. TCR clonality of endogenous CD4 T cell infiltrates in early inflammatory arthritis was asse
Externí odkaz:
https://doaj.org/article/f24f091353d845b49a310b48bae536ce
Autor:
Pascale Wehr, Daniela Sieghart, Shaima Al Khabouri, György Nagy, Michael Bonelli, Gavin R. Meehan, Catharien M. U. Hilkens, James M. Brewer, Ranjeny Thomas, Paul Garside, Huw D. Lewis, David C. Wraith, David F. Tough
Publikováno v:
Annals of the Rheumatic Diseases
Increasingly earlier identification of individuals at high risk of rheumatoid arthritis (RA) (eg, with autoantibodies and mild symptoms) improves the feasibility of preventing or curing disease. The use of antigen-specific immunotherapies to reinstat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bffd263ffa34d2645071950755643de5
https://doi.org/10.1136/annrheumdis-2021-220043
https://doi.org/10.1136/annrheumdis-2021-220043
Autor:
Megan K. L. MacLeod, Jennifer L. Matsuda, Shaima Al Khabouri, Laurent Gapin, F. Morton, Paul Garside, John W. Kappler, Phillipa Marrack, Eric T. Clambey, Joshua I. Gray, Thomas D. Otto
Publikováno v:
Immunology
We have examined the response of memory CD4 T cells to tolerogenic signals. Although memory CD4 T cells could respond to antigen delivered without adjuvant, they undergo cell death upon further restimulation. Our data suggest that the Tcells die as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb423735c33a705e2c5667bdb7ece321
https://doi.org/10.1111/imm.13263
https://doi.org/10.1111/imm.13263
Autor:
James M. Brewer, Joshua I. Gray, Robert A. Benson, Paul Garside, Catriona T. Prendergast, Thomas D. Otto, Shaima Al Khabouri
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
ObjectivesDevelopment of effective tolerogenic therapies for Rheumatoid Arthritis (RA) relies on understanding the evolution of articular antigen specific CD4 T cell responses. TCR clonality of the endogenous CD4 T cell infiltrate in early inflammato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93a42528f6e4c9f260c73385a71b820f
https://www.frontiersin.org/articles/10.3389/fimmu.2021.669856/full
https://www.frontiersin.org/articles/10.3389/fimmu.2021.669856/full
Autor:
Carmen Gerlach, Shaima Al Khabouri
Publikováno v:
Scandinavian Journal of Immunology
T cells responding to acute infections generally provide two key functions to protect the host: (1) active contribution to pathogen elimination and (2) providing long‐lived cells that are poised to rapidly respond to renewed infection, thus ensurin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc084b8bf82dc491213e9c995bf4a13a
http://europepmc.org/articles/PMC7757170
http://europepmc.org/articles/PMC7757170
Autor:
James M. Brewer, Robert A. Benson, Catriona T. Prendergast, Iain B. McInnes, Shaima Al-Khabouri, Agapitos Patakas, Paul Garside, Claire L. McIntyre
Publikováno v:
Annals of the rheumatic diseases. 77(4)
ObjectivesSuccessful early intervention in rheumatoid arthritis (RA) with the aim of resetting immunological tolerance requires a clearer understanding of how specificity, cellular kinetics and spatial behaviour shape the evolution of articular T cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d72e7b439a6726ba8eef40583cdc8d06
https://pubmed.ncbi.nlm.nih.gov/29358281
https://pubmed.ncbi.nlm.nih.gov/29358281
Autor:
Zachary Z. Sun, Julius B. Lucks, Jongmin Kim, Christopher P. Fall, Richard M. Murray, Vipul Singhal, Kevin J. Spring, Clarmyra A. Hayes, Melissa K. Takahashi, Shaima Al-Khabouri, Vincent Noireaux, James Chappell
Publikováno v:
ACS Synthetic Biology
RNA regulators are emerging as powerful tools to engineer synthetic genetic networks or rewire existing ones. A potential strength of RNA networks is that they may be able to propagate signals on time scales that are set by the fast degradation rates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b6a34d5e37574f51be7b5810564bb49
https://doi.org/10.1021/sb400206c
https://doi.org/10.1021/sb400206c
Autor:
Agathe K Streiff, Joao Suzuki, Enas Mahrous, Seang Lin Tan, Hugh J. Clarke, Isabelle Demeestere, Shaima Al-Khabouri
Publikováno v:
Biology of Reproduction. 87
During folliculogenesis, oocytes grow and acquire developmental competence in a mutually dependent relationship with their adjacent somatic cells. Follicle-stimulating hormone (FSH) plays an essential and well-established role in the differentiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e367f040b14fa5aa51013db00b3d13c1
https://doi.org/10.1095/biolreprod.112.099929
https://doi.org/10.1095/biolreprod.112.099929
Autor:
Isabelle, Demeestere, Agathe K, Streiff, João, Suzuki, Shaima, Al-Khabouri, Enas, Mahrous, Seang Lin, Tan, Hugh J, Clarke
Publikováno v:
Biology of reproduction. 87(1)
During folliculogenesis, oocytes grow and acquire developmental competence in a mutually dependent relationship with their adjacent somatic cells. Follicle-stimulating hormone (FSH) plays an essential and well-established role in the differentiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::06ccfc60bcba934a793ccab5602f37bb
https://pubmed.ncbi.nlm.nih.gov/22517620
https://pubmed.ncbi.nlm.nih.gov/22517620