Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Shailja, Raje"'
Autor:
Shailja Raje, Ritu Barthwal
Publikováno v:
International Journal of Biological Macromolecules. 139:1272-1287
Recent reports suggest influence of anti-cancer anthracyclines on telomere dysfunction and their possible interaction with G-quadruplex (G4) DNA as an alternate pathway to apoptosis. We have investigated interaction of epirubicin and adriamycin with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a7573e5a63a6a65bc98db8b820e74d8
https://doi.org/10.1016/j.ijbiomac.2019.08.109
https://doi.org/10.1016/j.ijbiomac.2019.08.109
Publikováno v:
Journal of biomolecular structuredynamics. 39(3)
Anthracycline anticancer drugs show multiple strategies of action on gene functioning by regulation of telomerase enzyme by apoptotic factors, e.g. ceramide level, p53 activity, bcl-2 protein levels, besides inhibiting DNA/RNA synthesis and topoisome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::bb7d4308ff04dcc3681902e2fa301e48
https://pubmed.ncbi.nlm.nih.gov/32070245
https://pubmed.ncbi.nlm.nih.gov/32070245
Publikováno v:
Journal of Molecular Recognition. 33
Adriamycin is known to exert its anti cancer action by inhibiting DNA duplication, RNA transcription and topoisomerase-II enzyme action. Recent findings of its binding to G-quadruplex DNA resulting in telomere dysfunction indicated multiple strategie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cca1ed70fb85f1a20f540baf7ca6e685
https://doi.org/10.1002/jmr.2815
https://doi.org/10.1002/jmr.2815
Publikováno v:
Journal of molecular recognition : JMRREFERENCES. 33(2)
Adriamycin is known to exert its anti cancer action by inhibiting DNA duplication, RNA transcription and topoisomerase-II enzyme action. Recent findings of its binding to G-quadruplex DNA resulting in telomere dysfunction indicated multiple strategie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b05f3b71d3cb6be2a985a09ce8b0fbf
https://pubmed.ncbi.nlm.nih.gov/31793724
https://pubmed.ncbi.nlm.nih.gov/31793724
Publikováno v:
Bioorganicmedicinal chemistry. 27(24)
Epirubicin exerts its anti cancer action by blocking DNA/RNA synthesis and inhibition of topoisomerase-II enzyme. Recent reports on its influence on telomere maintenance, suggest interaction with G-quadruplex DNA leading to multiple strategies of act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bcd58f474c267544f1802eaa5f685c7e
https://pubmed.ncbi.nlm.nih.gov/31685331
https://pubmed.ncbi.nlm.nih.gov/31685331
Autor:
Shailja, Raje, Ritu, Barthwal
Publikováno v:
International journal of biological macromolecules. 139
Recent reports suggest influence of anti-cancer anthracyclines on telomere dysfunction and their possible interaction with G-quadruplex (G4) DNA as an alternate pathway to apoptosis. We have investigated interaction of epirubicin and adriamycin with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::afe3913c5c42ed1b64b072baee2753df
https://pubmed.ncbi.nlm.nih.gov/31421170
https://pubmed.ncbi.nlm.nih.gov/31421170
Publikováno v:
Bioorganic & Medicinal Chemistry. 28:115761
Anthracycline anticancer drugs show multiple strategies of action on gene functioning by regulation of telomerase enzyme by apoptotic factors, e.g. ceramide level, p53 activity, bcl-2 protein levels, besides inhibiting DNA/RNA synthesis and topoisome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c880ca0dc66878f5bfb9a8730bb34a4
https://doi.org/10.1016/j.bmc.2020.115761
https://doi.org/10.1016/j.bmc.2020.115761