Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Shailesh Y. Desai"'
Autor:
Luca Cucullo, Matteo Marroni, Stephen M. Dombrowski, Damir Janigro, Marc R. Mayberg, Ljiljana Bengez, Kris Goodrich, Shailesh Y. Desai, William Bingaman
Publikováno v:
Epilepsia. 42:1501-1506
Summary: Purpose: It has been suggested that altered drug permeability across the blood–brain barrier (BBB) may be involved in pharmacoresistance to antiepileptic drugs (AEDs). To test this hypothesis further, we measured multiple drug resistance (
Publikováno v:
Genes & Development. 11:2029-2039
The c-ski proto-oncogene has been implicated in the control of cell growth and skeletal muscle differentiation. To determine its normal functions in vivo, we have disrupted the mouse c-ski gene. Our results show a novel role for ski in the morphogene
Autor:
Shailesh Y. Desai, Mie-Jae Im, Tanya Das, Kwang Jin Baek, Caroline D. Gray, Michael Ludwig, Ratan Gacchui, Ki-Chul Hwang
Publikováno v:
Biochemistry. 35:2651-2657
Regulation of cellular response is an important mechanism for controlling cellular functions. The transmembrane signaling of the hormone receptors is regulated by GTP-binding proteins (GTPases) and their associated proteins. Our previous studies demo
Autor:
Robert H. Silverman, Ara G. Hovanessian, Ratan K. Maitra, Nigel A.J. McMillan, Shailesh Y. Desai, Bryan R.G. Williams, Ganes C. Sen, James McSwiggen
Publikováno v:
Virology. 204:823-827
The TAR sequence at the 5'-termini of all HIV-1 mRNA species forms a stable structure that is responsible for both transcriptional and translational regulation of HIV-1. Previously we and others reported that purified TAR RNA synthesized by in vitro
Autor:
Bruce M. Prenner, Eli O. Meltzer, Bingxia Wang, John Karafilidis, Shailesh Y. Desai, John W. Walsh
Publikováno v:
A31. OPTIMIZING THERAPEUTIC STRATEGIES IN AIRWAYS DISEASE.
Autor:
Nikolay V. Vasilyev, Shailesh Y. Desai, Muhammad Ali Mumtaz, Chad M. Nicholls, Roger B.B. Mee, Raja Joshi, Brian W. Duncan, Charles H. Fraga
Publikováno v:
The Journal of thoracic and cardiovascular surgery. 129(1)
doi:10.1016/j.jtcvs.2004.04.006 Pulmonary arteriovenous malformations (PAVMs) are abnormal blood vessels that develop in a significant number of patients undergoing cavopulmonary anastomosis (CPA). PAVMs result in hypoxemia and decreased exercise tol
Autor:
Matteo, Marroni, Kelly M, Kight, Mohammed, Hossain, Luca, Cucullo, Shailesh Y, Desai, Damir, Janigro
Publikováno v:
Methods in molecular medicine. 89
Autor:
Kelly Kight, Edward F. Plow, Shailesh Y. Desai, Eric J. Topol, Damir Janigro, Olga I. Stenina, Irene Krukovets
Publikováno v:
Circulation. 108(12)
Background— In a recent large-scale genetic association study, a single nucleotide polymorphism in the thrombospondin-4 (TSP-4) gene, resulting in a proline-for-alanine substitution at position 387, was associated with a significantly increased ris
Autor:
Sandra L. Starnes, Thomas K. Jones, Charles H. Fraga, Flavian M. Lupinetti, Sanjeev K. Mathur, Brian W. Duncan, Geoffrey L. Rosenthal, Shailesh Y. Desai
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 283(5)
We developed a rat model of pulmonary arteriovenous malformations after cavopulmonary anastomosis. We sought to determine whether this model reproduces the angiographic and histologic features seen in the human condition. Eight Sprague-Dawley rats un