Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Shailendra Bordawekar"'
Autor:
Wei Pin Goh, Kushal Sinha, Nandkishor K. Nere, Raimundo Ho, Shailendra Bordawekar, Ahmad Sheikh, Mojtaba Ghadiri
Publikováno v:
Pharmaceutical Research. 39:3209-3221
Agitated filter bed dryer is often the equipment of choice in the pharmaceutical industry for the isolation of potent active pharmaceutical ingredients (API) from the mother liquor and subsequent drying through intermittent agitation. The use of an i
Autor:
Shailendra Bordawekar, William Jones, Raimundo Ho, Ahmad Y. Sheikh, Andrew D. Bond, Mihails Arhangelskis, Gabriela Schneider-Rauber, Nandkishor K. Nere
Publikováno v:
Acta Crystallographica Section B, Structural Science, Crystal Engineering and Materials
Labile multicomponent crystal forms of carbamazepine have been studied with an aim of identifying the structural and surface features that drive the outcome of thermal stress-induced transformations.
Stress-induced transformations of labile mult
Stress-induced transformations of labile mult
Autor:
Kushal Sinha, Rik Drummond-Brydson, James Cattle, William Jones, Shailendra Bordawekar, Gabriela Schneider-Rauber, Raimundo Ho, Mihails Arhangelskis, Ahmad Y. Sheikh, Nicole Hondow, Mojtaba Ghadiri, Nandkishor K. Nere, Wei-Pin Goh
Publikováno v:
Chemical Science
Crystal engineering has advanced the strategies for design and synthesis of organic solids with the main focus being on customising the properties of the materials. Research in this area has a significant impact on large-scale manufacturing, as indus
Autor:
Nandkishor K. Nere, Shailendra Bordawekar, Andrew D. Bond, Raimundo Ho, Ahmad Y. Sheikh, William Jones, Gabriela Schneider-Rauber
Publikováno v:
Crystal Growth & Design. 21:52-64
This paper reports on the solution growth of carbamazepine dihydrate and discusses the relative development of the {h00} and {0k0} faces as a function of the crystallization conditions. While the o...
Publikováno v:
AIChE Journal. 67
Publikováno v:
ACS Central Science, Vol 5, Iss 1, Pp 109-115 (2019)
ACS Central Science
ACS Central Science
Visible-light-promoted organic reactions can offer increased reactivity and selectivity via unique reaction pathways to address a multitude of practical synthetic problems, yet few practical solutions exist to employ these reactions for multikilogram
Molecular Dynamics Electric Field Crystallization Simulations of Paracetamol Produce a New Polymorph
Autor:
Hsien-Hsin Tung, Zoltan K. Nagy, Shailendra Bordawekar, Conor Parks, Nandkishor K. Nere, Andy Koswara, Doraiswami Ramkrishna
Publikováno v:
Crystal Growth & Design. 17:3751-3765
Using molecular dynamics simulations, we demonstrate the ability of high intensity, 1.5 V/nm, static electric fields to induce the formation of a new polymorph of paracetamol, one of the most important fever and pain suppressants in the world. In the
Autor:
Shailendra Bordawekar, Nandkishor K. Nere, Hsien-Hsin Tung, Andy Koswara, Conor Parks, Zoltan K. Nagy, Doraiswami Ramkrishna
Publikováno v:
Molecular Pharmaceutics. 14:1023-1032
Nanocrystals are receiving increased attention for pharmaceutical applications due to their enhanced solubility relative to their micron-sized counterpart and, in turn, potentially increased bioavailability. In this work, a computational method is pr
Autor:
Erwin Irdam, Christopher J. Welch, Aaron S. Cote, Jean W. Tom, Pierre Boulas, Joel M. Hawkins, Kenneth M. Wells, Charles D. Papageorgiou, David Dermot Patrick Laffan, Margaret M. Faul, Purdie Mark, Rahn McKeown, Scott A. May, Steven J. Wittenberger, Srinivas Tummala, Kevin D. Seibert, Nicholas Murray Thomson, Frederick Hicks, Antonio Christian Ferretti, Paul Frank Fernandez, Keith Horspool, Shailendra Bordawekar, Bing-Shiou Yang
Publikováno v:
Organic Process Research & Development. 21:414-419
The creation of the Enabling Technologies Consortium (ETC) is described. The ETC fosters precompetitive collaborations aimed at the development and evaluation of new enabling technologies for pharmaceutical research and development, with an initial f
Autor:
Conor Parks, Hsien-Hsin Tung, Zoltan K. Nagy, Doraiswami Ramkrishna, Andy Koswara, Nandkishor K. Nere, Frank DeVilbiss, Shailendra Bordawekar
Publikováno v:
Physical Chemistry Chemical Physics. 19:5285-5295
Current polymorph prediction methods, known as lattice energy minimization, seek to determine the crystal lattice with the lowest potential energy, rendering it unable to predict solvent dependent metastable form crystallization. Facilitated by embar