Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Shailender S. Kanwar"'
Autor:
Adhip P.N. Majumdar, Ramzi M. Mohammad, Arun K. Rishi, Fazlul H. Sarkar, Bhaumik B. Patel, Jianhua Du, Jayanta K. Das, Shailender S. Kanwar, Amro Aboukameel, Yingjie Yu, Jyoti Nautiyal
Many solid tumors, including breast cancer, show increased activation of several growth factor receptors, specifically epidermal growth factor receptor (EGFR) and its family members as well as c-Src, a nonreceptor tyrosine kinase that promotes prolif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eeada2741b34d1bebdca566b877512a
https://doi.org/10.1158/1535-7163.c.6531651
https://doi.org/10.1158/1535-7163.c.6531651
Autor:
Adhip P.N. Majumdar, Ramzi M. Mohammad, Arun K. Rishi, Fazlul H. Sarkar, Bhaumik B. Patel, Jianhua Du, Jayanta K. Das, Shailender S. Kanwar, Amro Aboukameel, Yingjie Yu, Jyoti Nautiyal
Supplementary Data from ErbB-Inhibitory Protein: A Modified Ectodomain of Epidermal Growth Factor Receptor Synergizes with Dasatinib to Inhibit Growth of Breast Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04b21d86fb2f776f5e5ff160715180e7
https://doi.org/10.1158/1535-7163.22484913
https://doi.org/10.1158/1535-7163.22484913
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 302:G655-G663
One of the most consistent pathological conditions in the gastrointestinal tract with advancing age is malignancy, particularly gastrointestinal cancers, the incidence of which increases sharply with aging. Although the reasons for the age-related ri
Autor:
Fazlul H. Sarkar, Bhaumik B. Patel, Adhip P.N. Majumdar, Jyoti Nautiyal, Yingjie Yu, Shailender S. Kanwar, Phil Sun Oh
Publikováno v:
Carcinogenesis. 33:68-76
Although microRNA-21 (miR-21) is emerging as an oncogene and has been shown to target several tumor suppressor genes, including programmed cell death 4 (PDCD4), its precise mechanism of action on cancer stem cells (CSCs) is unclear. Herein, we report
Autor:
Adhip P.N. Majumdar, Matthew A. Sanders, Bhaumik B. Patel, Shailender S. Kanwar, Vaishali B. Patel, Phil Sun Oh, Yingjie Yu, Jyoti Nautiyal
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 301:G347-G355
We have previously demonstrated that expression of the novel gene schlafen-3 (Slfn-3) correlates with intestinal epithelial cell differentiation (Patel VB, Yu Y, Das JK, Patel BB, Majumdar AP. Biochem Biophys Res Commun 388: 752–756, 2009). The pre
Publikováno v:
Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics. 18:243-257
Evidence suggests that nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit cycloxygenase (COX) and production of the proinflammatory prostaglandin, PGE2, and thus prevent carcinogenesis in the colon. Indeed, one of the specific COX-2 inhibitors, ce
Publikováno v:
Journal of Environmental Pathology, Toxicology and Oncology. 27:295-302
The present study was designed to investigate the effects of a selective cycloogenase-2 (COX-2) inhibitor, etoricoxib, on the membrane-specific enzymes, lipid composition, and changes in fluidity parameters of rat colonic plasma membrane. Two doses o
Publikováno v:
Chemistry & Biodiversity. 3:1102-1115
Functional interactions of lipids and proteins were examined in brush-border membranes isolated from the kidney cortex by studying the temperature dependence of the hydrolytic enzyme activities. A close relationship was observed for the membrane prot
Publikováno v:
Toxicology Mechanisms and Methods. 16:307-312
Monensin, a carboxylic ionophore, is well known for Na(+)/H(+) exchanger activity across biological membranes. It is also used in the poultry industry for its useful effects as a food additive. The present study has been designed to investigate the e
Autor:
Shailender S. Kanwar, Bimla Nehru
Publikováno v:
Biological Trace Element Research. 101:257-264
Lead (Pb) is known to disrupt the pro-oxidant/antioxidant balance of tissues, which leads to biochemical and physiological dysfunction. Oxidative stress is considered a possible molecular mechanism involved in Pb neurotoxicity. Considering the vulner