Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Shailender Nagpal"'
Autor:
Matthew Schwede, Shailender Nagpal, Michael J. Gandal, Neelroop N. Parikshak, Karoly Mirnics, Daniel H. Geschwind, Eric M. Morrow
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 10, Iss 1, Pp 1-9 (2018)
Abstract Background Genetic studies in autism have pinpointed a heterogeneous group of loci and genes. Further, environment may be an additional factor conferring susceptibility to autism. Transcriptome studies investigate quantitative differences in
Externí odkaz:
https://doaj.org/article/a43d93e689e243578493a25a6b22a5a9
Autor:
Joseph G. Hacia, Mazen W. Karaman, Shailender Nagpal, Danny Chawannakul, Vincent V. Ho, John E. Biaglow, Mimi Mesfin, Dale Miles, Cheryl Lepp, Richard A. Miller, Philip Lecane, Darren Magda
Supplementary Methods from Motexafin Gadolinium Disrupts Zinc Metabolism in Human Cancer Cell Lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ddd411520d7bdb66b06744f30a7001b
https://doi.org/10.1158/0008-5472.22364985
https://doi.org/10.1158/0008-5472.22364985
Autor:
Joseph G. Hacia, Mazen W. Karaman, Shailender Nagpal, Danny Chawannakul, Vincent V. Ho, John E. Biaglow, Mimi Mesfin, Dale Miles, Cheryl Lepp, Richard A. Miller, Philip Lecane, Darren Magda
To gain a better understanding of the mechanism of action of the metal cation–containing chemotherapeutic drug motexafin gadolinium (MGd), gene expression profiling analyses were conducted on plateau phase human lung cancer (A549) cell cultures tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93fb0062de37344a6661265c9df619aa
https://doi.org/10.1158/0008-5472.c.6494472.v1
https://doi.org/10.1158/0008-5472.c.6494472.v1
Autor:
Schwede, Matthew, Shailender Nagpal, Gandal, Michael, Neelroop Parikshak, Karoly Mirnics, Geschwind, Daniel, Morrow, Eric
Figure S2. Heatmaps of mitochondrial genes in the Chow et al. and Garbett et al. microarray datasets. The rows are genes and the columns are subjects; the top vertical bar shows whether a subject was from autism (blue) or control (red). Generally, lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15aad1491edede7fca90e2391e1046fd
Autor:
Schwede, Matthew, Shailender Nagpal, Gandal, Michael, Neelroop Parikshak, Karoly Mirnics, Geschwind, Daniel, Morrow, Eric
Figure S1. Venn diagram depicting the overlap of participants between the RNA-seq dataset and the three microarray datasets analyzed in this study. See the “Participants” section under the “Methods” section for more information on each study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3497a10f21c6b2cb6b7d760903dd90d5
Publikováno v:
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 168:720-729
Oxytocin regulates social behavior in animal models. Research supports an association between genetic variation in the oxytocin receptor gene (OXTR) and autism spectrum disorders (ASD). In this study, we examine the association between the OXTR gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea020024ed2390214ecd37606149ba02
https://doi.org/10.1002/ajmg.b.32377
https://doi.org/10.1002/ajmg.b.32377
Autor:
Matthew Schwede, R. Sean Hill, Anna Rajab, Ramzi Nasir, Muna Al-Saffar, Eric M. Morrow, Michael Schmidt, Sofia B. Lizarraga, Shailender Nagpal, Anh Thu N. Lam, Shawn M. Davidson, Sasmita Mishra, Mirrat Gul Butt, Haroon Rashid Chaudhry, Malak Ei-Quessny, Afzal Javed, Ralph J. DeBerardinis, Syed Imran Murtaza, Tojo Nakayama, Seung Yun Yoo, Ozan Baytas, Ganeshwaran H. Mochida, Chendong Yang, David E. Housman, A. James Barkovich, Jennifer N. Partlow, Saima Niaz, Dylan J. Vaughan, Qing Ouyang
Publikováno v:
Proceedings of the National Academy of Sciences. 113
Mutations that cause neurological phenotypes are highly informative with regard to mechanisms governing human brain function and disease. We report autosomal recessive mutations in the enzyme glutamate pyruvate transaminase 2 (GPT2) in large kindreds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab2f19330a4157416e151a12a5d6ee61
https://doi.org/10.1073/pnas.1609221113
https://doi.org/10.1073/pnas.1609221113
Publikováno v:
Genomics. 99(1):44-51
Genome-wide characterization of the retinal transcriptome is central to understanding development, physiology and disorders of the visual system. Massively parallel, short-read sequencing of mRNA libraries was used to generate an extensive map of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f31a9e6e079e09b57491b2cc0b25f1d
Autor:
Danny Chawannakul, Mazen W. Karaman, Vincent V. Ho, Cheryl Lepp, Shailender Nagpal, Dale Miles, John E. Biaglow, Mimi Mesfin, Richard A. Miller, Joseph G. Hacia, Philip Lecane, Darren Magda
Publikováno v:
Cancer Research. 65:3837-3845
To gain a better understanding of the mechanism of action of the metal cation–containing chemotherapeutic drug motexafin gadolinium (MGd), gene expression profiling analyses were conducted on plateau phase human lung cancer (A549) cell cultures tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::041affb0078d02b0a6a2f921ab328211
https://doi.org/10.1158/0008-5472.can-04-4099
https://doi.org/10.1158/0008-5472.can-04-4099
Autor:
Ece D. Gamsiz, Eric M. Morrow, Stephen Sanders, Bernie Devlin, Michael Schmidt, Elizabeth W. Triche, Shailender Nagpal, Edwin H. Cook, Michael T. Murtha, Daniel H. Geschwind, Sorin Istrail, Emma W. Viscidi, Matthew W. State, Abbie M. Frederick
Publikováno v:
American journal of human genetics, vol 93, iss 1
Intellectual disability (ID), often attributed to autosomal-recessive mutations, occurs in 40% of autism spectrum disorders (ASDs). For this reason, we conducted a genome-wide analysis of runs of homozygosity (ROH) in simplex ASD-affected families co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be23562f4666b144736178187de0892e
https://escholarship.org/uc/item/2cr2b10z
https://escholarship.org/uc/item/2cr2b10z