Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Shaileja Chopra"'
Autor:
Shaileja Chopra, Andrés Palencia, Cornelia Virus, Sarah Schulwitz, Brenda R. Temple, Stephen Cusack, John Reader
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
The bacterium Agrobacterium radiobacter K84 secretes an antibiotic that is transported into the plant pathogen A. tumefaciensand processed into the toxin TM84. Here, the authors identify a mechanism whereby the antibiotic-producing microbe resists it
Externí odkaz:
https://doaj.org/article/b0dc3d1e3ad24bb4b12e4d4913e3ff6d
Autor:
Rajendra Singh, Shaileja Chopra, Carrie Graham, Melissa Langer, Rainer Ng, Anirudh J. Ullal, Vamsee K. Pamula
Publikováno v:
Diagnostics, Vol 10, Iss 5, p 294 (2020)
Interest in newborn screening for mucopolysaccharidoses (MPS) is growing, due in part to ongoing efforts to develop new therapies for these disorders and new screening assays to identify increased risk for the individual MPSs on the basis of deficien
Externí odkaz:
https://doaj.org/article/652f704710e94b98956e40db95c445c8
Autor:
Rainer Ng, Carrie Graham, Anirudh J. Ullal, Vamsee K. Pamula, Melissa Langer, Shaileja Chopra, Rajendra Singh
Publikováno v:
Diagnostics, Vol 10, Iss 294, p 294 (2020)
Diagnostics
Diagnostics
Interest in newborn screening for mucopolysaccharidoses (MPS) is growing, due in part to ongoing efforts to develop new therapies for these disorders and new screening assays to identify increased risk for the individual MPSs on the basis of deficien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28b0fc9ea7a36edaa9d5f666fa9a18aa
https://www.mdpi.com/2075-4418/10/5/294
https://www.mdpi.com/2075-4418/10/5/294
Autor:
John S. Reader, Cornelia Virus, Sarah Schulwitz, Shaileja Chopra, Brenda Temple, Andrés Palencia, Stephen Cusack
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
'Nature Communications ', vol: 7, pages: 12928-1-12928-13 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
'Nature Communications ', vol: 7, pages: 12928-1-12928-13 (2016)
Antibiotic-producing microbes evolved self-resistance mechanisms to avoid suicide. The biocontrol Agrobacterium radiobacter K84 secretes the Trojan Horse antibiotic agrocin 84 that is selectively transported into the plant pathogen A. tumefaciens and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c62c9373c93f25a364f909ee9f5ec33
Publikováno v:
Molecular Genetics and Metabolism. 123:S107
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e22a67a8fc6484b9dce938eafa6073b
https://doi.org/10.1016/j.ymgme.2017.12.284
https://doi.org/10.1016/j.ymgme.2017.12.284
Autor:
Carrie Graham, Rainer Ng, Miriam Nuffer, Rajendra Singh, Pranathi Vadlamani, Vamsee K. Pamula, Lisa Nelson, Scott Norton, Shaileja Chopra
Publikováno v:
Molecular Genetics and Metabolism. 123:S132
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb4ebe0cf0b8fdef43818f15dd60939d
https://doi.org/10.1016/j.ymgme.2017.12.361
https://doi.org/10.1016/j.ymgme.2017.12.361
Publikováno v:
Journal of Biological Chemistry. 283:4690-4698
R67 dihydrofolate reductase (DHFR) catalyzes the reduction of dihydrofolate (DHF) to tetrahydrofolate using NADPH as a cofactor. This enzyme is a homotetramer possessing 222 symmetry, and a single active site pore traverses the length of the protein.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ba275ce5fd5ffe8cd1ac5b250812d43
https://doi.org/10.1074/jbc.m709443200
https://doi.org/10.1074/jbc.m709443200
Autor:
Michael Brad Strader, Shaileja Chopra, Michael R. Duff, Elizabeth E. Howell, Pratul K. Agarwal
Publikováno v:
Biochemistry
Homotetrameric R67 dihydrofolate reductase possesses 222 symmetry and a single active site pore. This situation results in a promiscuous binding site that accommodates either the substrate, dihydrofolate (DHF), or the cofactor, NADPH. NADPH interacts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0be03ac519ccd86c2b79f5fdb905c260
https://pubmed.ncbi.nlm.nih.gov/26637016
https://pubmed.ncbi.nlm.nih.gov/26637016
Autor:
Lori G. Stinnett, Jun Wu, R. Derike Smiley, Michael Jackson, Elizabeth E. Howell, Michael Brad Strader, Shaileja Chopra
Publikováno v:
Biochemistry. 43:7403-7412
R67 dihydrofolate reductase (DHFR) is a novel protein that possesses 222 symmetry. A single active site pore traverses the length of the homotetramer. Although the 222 symmetry implies that four symmetry-related binding sites should exist for each su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::558427096926d7ee8d7ce6aa70f71bef
https://doi.org/10.1021/bi049646k
https://doi.org/10.1021/bi049646k
Autor:
John S. Reader, Shaileja Chopra
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 16, Iss 1, Pp 321-349 (2014)
International Journal of Molecular Sciences, Vol 16, Iss 1, Pp 321-349 (2014)
Transfer RNAs (tRNAs) are central players in the protein translation machinery and as such are prominent targets for a large number of natural and synthetic antibiotics. This review focuses on the role of tRNAs in bacterial antibiosis. We will discus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6693a9ac7256a896342c85c1fa9f5d9